scholarly journals Maintenance pharmacotherapy of unipolar depression

1999 ◽  
Vol 23 (6) ◽  
pp. 370-373 ◽  
Author(s):  
Som Forshall ◽  
David J. Nutt
Keyword(s):  
Prophylactic Treatment ◽  
Unipolar Depression ◽  
Term Treatment ◽  
Current Evidence ◽  
Full Remission ◽  
Long Term Treatment ◽  
Continuation Treatment ◽  
Term Maintenance ◽  
Review Current

Aims and methodsThe purpose of this paper is to review current evidence and opinion with regard to the long-term treatment of unipolar depression. The method employed was a Psychlit search using the search items long-term, maintenance, treatment and depression.ResultsThe search yielded 91 articles.Clinical implicationsUnipolar depression is frequently recurrent and sometimes a chronic illness. The paper identifies those at greatest risk of recurrence. It goes on to examine strategies to prevent relapse and for prophylactic treatment. It concludes that continuation treatment should be sustained at full dose for 4–6 months after full remission of symptoms. Where depression is highly recurrent the acute phase dose should be maintained in the long-term.

A Double-Blind Study of Long-Term Treatment With Sertraline or Fluvoxamine for Prevention of Highly Recurrent Unipolar Depression

1997 ◽  
Vol 58 (3) ◽  
pp. 104-107 ◽  
Author(s):  
Linda Franchini ◽  
Mariangela Gasperini ◽  
Jorge Perez ◽  
Enrico Smeraldi ◽  
Raffaella Zanardi
Keyword(s):  
Unipolar Depression ◽  
Term Treatment ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Long Term Treatment

Clonazepam in the long-term treatment of patients with unipolar depression, bipolar and schizoaffective disorder

2003 ◽  
Vol 13 (2) ◽  
pp. 129-134 ◽  
Author(s):  
Dietmar Winkler ◽  
Matthäus Willeit ◽  
Rainer Wolf ◽  
Mara Stamenkovic ◽  
Johannes Tauscher ◽  
...  
Keyword(s):  
Schizoaffective Disorder ◽  
Unipolar Depression ◽  
Term Treatment ◽  
Long Term Treatment

scholarly journals MANAGEMENT OF ENDOCRINE DISEASE: Treatment breaks in long-term management of osteoporosis

2019 ◽  
Vol 180 (1) ◽  
pp. R29-R35 ◽  
Author(s):  
Bente L Langdahl
Keyword(s):  
Management Plan ◽  
Term Treatment ◽  
Response To Treatment ◽  
Current Evidence ◽  
Endocrine Disease ◽  
Common Chronic Disease ◽  
Long Term Treatment ◽  
Future Fracture ◽  
Term Management

Osteoporosis is a common chronic disease and therefore a long-term management plan based on disease severity, comorbidities, other pharmacological treatments, gender, age and patient preferences is necessary. Consideration of treatment breaks may be included in the long-term management plan if the patient has been treated with a bisphosphonate, the disease is less severe, the response to treatment has been satisfactory and the risk of future fracture is estimated to be low. This perspective reviews the current evidence for long-term treatment with bisphosphonates and off treatment effects. Approaches to decision making and monitoring of treatment breaks are discussed.

scholarly journals Principles of follow-up assessments in patients with breast cancer after radical treatment

2017 ◽  
Vol 89 (3) ◽  
pp. 36-39 ◽  
Author(s):  
Diana Hodorowicz-Zaniewska ◽  
Krzysztof Herman
Keyword(s):  
Breast Cancer ◽  
Early Recurrence ◽  
Term Treatment ◽  
Social Consequences ◽  
The Other ◽  
Radical Treatment ◽  
Long Term Treatment ◽  
Review Current

A follow-up assessment plan after radical treatment is a part of a comprehensive approach to treating patients with breast cancer. Because breast cancer is the most frequent cancer both worldwide and in Poland, adequate follow-up is important not only for patients but also for economic reasons. Herein, we review current recommendations for follow-up assessments in patients with breast cancer. The main aim of such assessment is detection of early recurrence or tumor presence in the other breast, observation of long-term treatment complications, and creation of multidisciplinary infrastructure that will allow to reduce the risk of recurrence and alleviate physical, mental, and social consequences of treatment.

Long-term treatment with citalopram in patients with highly recurrent forms of unipolar depression

2001 ◽  
Vol 105 (1-2) ◽  
pp. 129-133 ◽  
Author(s):  
Linda Franchini ◽  
Chiara Spagnolo ◽  
Raffaella Rampoldi ◽  
Raffaella Zanardi ◽  
Enrico Smeraldi
Keyword(s):  
Unipolar Depression ◽  
Term Treatment ◽  
Long Term Treatment

The long-term management of depression

1995 ◽  
Vol 9 (2_suppl) ◽  
pp. 191-198 ◽  
Author(s):  
Roger Lane
Keyword(s):  
Unipolar Depression ◽  
Term Treatment ◽  
Term Therapy ◽  
Continuation Therapy ◽  
Treatment Of Depression ◽  
Long Term Treatment ◽  
The Uk ◽  
Long Term Therapy ◽  
Term Management

The long-term outlook for patients with unipolar depression is often poor. As few as one-fifth will remain well and a similar number will suffer chronic depression. It is now standard practice to extend acute treatment into a 4–6 month period of continuation therapy, and the value of prophylactic treatment over longer periods is becoming more widely recognised. Care must, however, be exercised in choosing suitable long-term treatment. Relatively little work on the prophylactic efficacy of the tricyclic antidepressants has been carried out, although imipramine has been shown to be effective. The selective serotonin re-uptake inhibitors (SSRIs) have been studied extensively and may be the most suitable long-term treatment for depression. Sertraline is effective in preventing both relapse and recurrence of depression and was the first agent specifically indicated for the long-term treatment of depression in the UK. In addition to clinical efficacy, many other factors favour SSRIs in the long-term management of depression. The tolerability of a drug is of major importance in long-term therapy since it affects compliance. Other important considerations include toxicity, safety in overdose, drug interaction potential, psychomotor effects and accident liability.

Achieving Long-Term Optimal Outcomes in Geriatric Depression and Anxiety

CNS Spectrums ◽  
2003 ◽  
Vol 8 (S3) ◽  
pp. 27-34 ◽  
Author(s):  
Benoit H. Mulsant ◽  
Ellen Whyte ◽  
Eric J. Lenze ◽  
Francis Lotrich ◽  
Jordan F. Karp ◽  
...  
Keyword(s):  
Older Patients ◽  
The Elderly ◽  
Term Treatment ◽  
Depression And Anxiety ◽  
Optimal Outcomes ◽  
Full Remission ◽  
Education Of Patients ◽  
Long Term Treatment ◽  
Medication Side

AbstractDepression and anxiety disorders are very common in the elderly. Data accumulated over the past 2 decades have shown that most older patients can tolerate and respond to acute treatment with serotonergic antidepressants, other psychotropic agents, or manual-based psychotherapy. However, outcomes under usual-care conditions remain poor. This review proposes that clinicians may significantly improve the long-term outcomes of their older patients with depression and anxiety by focusing on four key factors: (1) identification and treatment of comorbid conditions; (2) full remission of acute symptoms; (3) education of patients, families, and professional colleagues about the need for long-term treatment; and (4) prevention and management of medication side-effects.

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