scholarly journals The Distribution of Calcium between Blood and Cerebro-spinal Fluid in Mental Diseases. (Amer. Journ. Psychiat., July, 1931.) Katzenelbogen, S., and Goldsmith, H.

1932 ◽  
Vol 78 (320) ◽  
pp. 239-239
Author(s):  
M. Hamblin Smith
Keyword(s):  
Spinal Fluid ◽  
Mental Diseases

The Cholesterol Content of the Cerebro-spinal Fluid in Certain Mental Diseases

1926 ◽  
Vol 72 (296) ◽  
pp. 62-66 ◽  
Author(s):  
E. G. T. Poynder ◽  
J. Russell
Keyword(s):  
Cholesterol Content ◽  
County Council ◽  
Spinal Fluid ◽  
Mental Hospitals ◽  
Mental Diseases ◽  
The Subject

The presence of cholesterol in the cerebro-spinal fluid has been the subject of investigation by various observers. The following communication is based on a series of observations conducted at the Pathological Laboratory of the Maudsley Hospital, on specimens of cerebro-spinal fluid obtained from patients in the mental hospitals of the London County Council.

5. Pathology

1920 ◽  
Vol 66 (274) ◽  
pp. 308-309
Author(s):  
F. E. Stokes
Keyword(s):  
Spinal Fluid ◽  
Ammonium Salts ◽  
Dementia Praecox ◽  
High Nitrogen ◽  
General Paralysis ◽  
Mental Diseases ◽  
Three Stages ◽  
Pure Aqueous Solution ◽  
Very High ◽  
Diagnostic Importance

The method employed consists of three stages: (1) The conversion of the total nitrogen into ammonia by the Kjeldahl process; (2) the conversion of the ammonia into pure aqueous solution; and (3) the calorimetric estimation of the ammonia in this solution by means of Nessler's solution. The result is expressed as “nitrogen number,” which denotes the number of hundredths of a milligramme in 1 c.c. of cerebro-spinal fluid. In general paralysis there is a high nitrogen number, which is marked towards the termination of the disease. It may be low in the early stages or in remissions. In mania the nitrogen number is always low—a factor of diagnostic importance in distinguishing between this disease and maniacal phases occurring in general paralysis. In imbecility, dementia præcox, paranoia, amentia and epilepsy the nitrogen number varies, but is usually low, and in terminal dementias it is very high. It was also found that density and nitrogen numbers run parallel to one another, with the exception of epilepsy, where high density obtains. The author emphasises the fact that choline does not occur in the cerebro-spinal fluid in mental diseases, and that ammonium salts only occur in the merest traces.

Laboratory Aids to Diagnosis in Mental Diseases

1925 ◽  
Vol 71 (293) ◽  
pp. 192-218
Author(s):  
P. K. McCowan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Mental Disorders ◽  
Correct Diagnosis ◽  
Spinal Fluid ◽  
Diagnostic Specificity ◽  
Laboratory Methods ◽  
Mental Diseases ◽  
The Central Nervous System ◽  
The Many

For some time past there has been an increasing use of laboratory methods in the diagnosis of mental disorders. The following aims at offering further proof of the undoubted value of this method of approach in such cases. There seems, however, to be a growing tendency, not devoid of danger, to ascribe diagnostic specificity to one or other of the many tests in use for such examinations. Although it is undoubtedly true that an exhaustive analysis of a spinal fluid may in many cases lead to a correct diagnosis of the clinical condition of the patient from whom the specimen has been taken, it only requires a study of the literature to show that none of the reactions or group of reactions obtained from the spinal fluid can be regarded as pathognomonic of any disease of the central nervous system.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

A New Technique for the Light and Electron Microscopic Study of Individual Cerebro-Spinal Fluid Cells in a Mona Plane Layer

1976 ◽  
Vol 34 ◽  
pp. 362-363
Author(s):  
L.A. Dell
Keyword(s):  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Plane Layer ◽  
Ultrastructural Level ◽  
Spinal Fluid ◽  
Electron Microscopic Level ◽  
Electron Microscopic ◽  
Easy Method ◽  
Cell Pellet ◽  
A New Technique

A new method has been developed which readily offers the microscopist a possibility for both light and electron microscopic study of selected cells from the cerebrospinal fluid. Previous attempts to examine these cells in the spinal fluid at the ultrastructural level were based on modifications of cell pellet techniques developed for peripheral blood. These earlier methods were limited in application by the number of cells in spinal fluid required to obtain a sufficient size pellet and by the lack of an easy method of cellular identification between the light and electron microscopic level. The newly developed method routinely employs microscope slides coated with Siliclad and tungsten oxide for duplicate cytocentrifuge preparations of diagnostic spinal fluid specimens. Work done by Kushida and Suzuki provided a basis for our use of the metal oxide.

Spinal Fluid Leakage After Skull Base Surgical Procedures

1984 ◽  
Vol 17 (3) ◽  
pp. 601-612 ◽  
Author(s):  
Donald L. Myers ◽  
Robert Thayer Sataloff
Keyword(s):  
Skull Base ◽  
Surgical Procedures ◽  
Spinal Fluid ◽  
Fluid Leakage
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