The Pathological Anatomy and Pathology of Epilepsy

1907 ◽  
Vol 53 (220) ◽  
pp. 1-84 ◽  
Author(s):  
John Turner
Keyword(s):  
Medical Journal ◽  
Blood Stream ◽  
Idiopathic Epilepsy ◽  
Microscopical Examination ◽  
Pathological Anatomy ◽  
Short Account ◽  
Abnormal State ◽  
Grand Mal ◽  
Central Nervous Systems ◽  
The Individual

The following pages contain an account of the microscopical examination of the central nervous systems of forty-one cases of idiopathic epilepsy, which form the data on which I base my thesis that epilepsy is a disease occurring in persons with a defect of the nervous system either congenital or involutional, and in whom also there is an abnormal state of the blood, characterised by a special tendency to intravascular clotting, and that the fits, whether of the nature of grand mal or petitmal,owe their exciting cause to sudden stasis of the blood stream in some (generally limited) portion of the cortex, resulting from the blocking of cerebral cortical vessels by these aforementioned intravascular clots. I have already in a paper read at the pathological meeting of the Neurological Society in December, 1905, and published in the British Medical Journal March 3rd, 1906, given a short account of my views, but it was impossible in the limit of time at my disposal when reading the paper to deal in any but a very cursory way with many interesting aspects of the question, nor could I then give sufficient details of the microscopical examination of the individual cases.

scholarly journals Multi-Biometric System Based on Cutting-Edge Equipment for Experimental Contactless Verification

Sensors ◽  
2019 ◽  
Vol 19 (17) ◽  
pp. 3709 ◽  
Author(s):  
Lukas Kolda ◽  
Ondrej Krejcar ◽  
Ali Selamat ◽  
Kamil Kuca ◽  
Oluwaseun Fadeyi
Keyword(s):  
Hamming Distance ◽  
Blood Stream ◽  
Data Generation ◽  
Biometric System ◽  
Biometric Verification ◽  
Verification Methods ◽  
Theoretical Evidence ◽  
The Individual ◽  
Modified Hausdorff Distance ◽  
Individual Metrics

Biometric verification methods have gained significant popularity in recent times, which has brought about their extensive usage. In light of theoretical evidence surrounding the development of biometric verification, we proposed an experimental multi-biometric system for laboratory testing. First, the proposed system was designed such that it was able to identify and verify a user through the hand contour, and blood flow (blood stream) at the upper part of the hand. Next, we detailed the hard and software solutions for the system. A total of 40 subjects agreed to be a part of data generation team, which produced 280 hand images. The core of this paper lies in evaluating individual metrics, which are functions of frequency comparison of the double type faults with the EER (Equal Error Rate) values. The lowest value was measured for the case of the modified Hausdorff distance metric - Maximally Helicity Violating (MHV). Furthermore, for the verified biometric characteristics (Hamming distance and MHV), appropriate and suitable metrics have been proposed and experimented to optimize system precision. Thus, the EER value for the designed multi-biometric system in the context of this work was found to be 5%, which proves that metrics consolidation increases the precision of the multi-biometric system. Algorithms used for the proposed multi-biometric device shows that the individual metrics exhibit significant accuracy but perform better on consolidation, with a few shortcomings.

scholarly journals Comparison of the results of the ELISA, histochemical, and immunohistochemical detection of soya proteins in meat products    

2011 ◽  
Vol 29 (No. 5) ◽  
pp. 471-479 ◽  
Author(s):  
M. Pospiech ◽  
B. Tremlová ◽  
E. Renčová ◽  
RandulováZ ◽  
Z. Řezáčová Lukášková ◽  
...  
Keyword(s):  
Meat Products ◽  
Protein Detection ◽  
Soya Protein ◽  
Microscopical Examination ◽  
Immunochemical Method ◽  
Immunohistochemical Methods ◽  
Immunochemical Methods ◽  
Soya Proteins ◽  
The Individual ◽  
Comparison Of The Results

This work compares the commonly used immunochemical methods for soya protein detection and alternative microscopic methods. Immunochemical methods were represented by the competitive ELISA method. Histochemical and immunohistochemical methods were used for microscopical examination. From a group of 252 meat products, each sample was examined for soya proteins by ELISA, histochemical, and immunohistochemical methods. The products came from the following categories: cooked sausages, ham, dry cooked sausages, and fermented sausages. The results showed that the highest accuracy was achieved by immunohistochemical examination. However, in the category of cooked sausages, this result was not statistically significant. Since the results in the individual categories differed, our results demonstrate that one single method does not always provide reliable and completely objective results. Immunohistochemical methods seem to be the most suitable for the verification of the reference immunochemical method results and prevention of false results.

scholarly journals Humour and Social Protest: An Introduction

2007 ◽  
Vol 52 (S15) ◽  
pp. 1-20 ◽  
Author(s):  
Marjolein 't Hart
Keyword(s):  
Social Movement ◽  
Collective Identity ◽  
Social Protest ◽  
Communication Tool ◽  
Short Account ◽  
Garment Workers ◽  
Recent Developments ◽  
Political Opportunity Structures ◽  
Individual Contributions ◽  
The Individual

In the introduction to this volume, the author explains why social historians should study the relationship between humour and social protest in the past. The following questions are of interest. Under what conditions did laughter serve the cause of the protesters? How did humour strengthen social protest? And to what degree has humour been an effective tool for contentious social movements? Recent developments in the field of social movement theory regarding framing, collective identity, and emotions are combined with insights from humorology. A short account of the individual contributions follow: they range from the Zapatistas in Mexico to Vietnamese garment workers, from sixteenth-century Augsburg to Madrid and Stockholm in the 1990s. The findings point, above all, to the power of humour in the framing of political protest. Humour was used in quite different political opportunity structures, from open democratic societies to harsh repressive regimes. Often, humour furthered the development of the collective identity of a social movement, whereas in several cases humour acted as a powerful communication tool, serving as a true “weapon of the weak”.

Excitatory movements in a dog following propofol anesthesia

1996 ◽  
Vol 32 (4) ◽  
pp. 365-368 ◽  
Author(s):  
LE Smedile ◽  
T Duke ◽  
SM Taylor
Keyword(s):  
Foreign Body ◽  
Motor Activity ◽  
Intravenous Administration ◽  
Labrador Retriever ◽  
Idiopathic Epilepsy ◽  
Bronchial Foreign Body ◽  
Grand Mal ◽  
Horizontal Nystagmus

A two-year-old, neutered male Labrador retriever was anesthetized with intravenous propofol for bronchoscopy to remove a bronchial foreign body. The dog previously had been diagnosed with idiopathic epilepsy. During anesthetic recovery, the dog exhibited excitatory movements characterized by forelimb extensor rigidity, opisthotonos, generalized tremors, paddling, horizontal nystagmus, and facial twitching. Intravenous administration of pentobarbital temporarily stopped the motor activity. The excitatory movements persisted for 20 hours. The dog went on to recover completely, although he remained an epileptic, having one brief, generalized grand mal seizure every three-to-four months.

scholarly journals V.—On the Basaltic Rocks of the Midland Coal-fields

1870 ◽  
Vol 7 (70) ◽  
pp. 159-162 ◽  
Author(s):  
Samuel Allport
Keyword(s):  
Igneous Rocks ◽  
Microscopical Examination ◽  
Coal Field ◽  
The South ◽  
Short Account ◽  
Basaltic Rocks ◽  
Coal Fields

In the GeologicalMagazine for March last, Vol. VI., p. 115, I gave a short account of the discovery of Olivine and its pseudomorphs in the igneous rocks of the South Staffordshire Coal-field, and as I have since then made a microscopical examination of similar rocks from the surrounding district, I am induced to offer the following observations.

scholarly journals THE CARCINOGENIC EFFECT OF A PAPILLOMA VIRUS ON THE TARRED SKIN OF RABBITS

1938 ◽  
Vol 68 (4) ◽  
pp. 529-562 ◽  
Author(s):  
John G. Kidd ◽  
Peyton Rous
Keyword(s):  
Virus Infection ◽  
Blood Stream ◽  
Epidermal Cells ◽  
Subsequent Paper ◽  
Carcinogenic Effect ◽  
Highly Pathogenic ◽  
Papilloma Virus ◽  
Long Period ◽  
The Individual ◽  
Do So

A considerable variety of tumors, both benign and malignant, result from the localization of the rabbit papilloma virus in skin which has been prepared by repeated tarrings. They appear only in individuals highly susceptible to the action of the virus, and are more likely to be engendered by highly pathogenic inocula. No evidence has been found that differences in the potentialities of the virus entities are responsible for the diversity of the growths. This is referable to changes in the epidermal cells; and much more preliminary tarring is required to produce these changes than suffices to cause localization of the virus out of the blood stream with a resulting papillomatosis of the ordinary sort. The character of the individual anomalous tumors depends in some degree upon the extent of the preparatory changes in the cells, malignant growths being more frequent when the epidermis has been tarred for a relatively long period. All are focal or punctate in origin, and they exhibit their peculiar characters from the first, none being due to secondary alterations in ordinary papillomas. Tarring after the virus has localized in the epidermis does not significantly increase their number. They are the outcome of the state of the cells at the time of virus infection. Tarring exerts important influences in addition to changing the cells in such a way that unusual tumors result from the action of the virus. The procedure is notably effective in determining localization of the virus out of the blood stream; enables it to produce growths when otherwise it would not do so though present in the tarred skin; stimulates the proliferation of the tumors engendered; makes them disorderly and aggressive; and hastens the anaplasia of such of them as are malignant. It has similar effects upon the tar tumors, as will be demonstrated in a subsequent paper.

scholarly journals Finland, a Vocal Symphony for Soprano, Tenor and Large Orchestra

ICONI ◽  
2020 ◽  
pp. 100-111
Author(s):  
Anton А. Rovner ◽  
Keyword(s):  
Large Scale ◽  
Main Idea ◽  
Musical Composition ◽  
Musical Language ◽  
Twelve Tone ◽  
Early 19Th Century ◽  
Short Account ◽  
Romantic Poet ◽  
The Individual ◽  
Hand Writing

My composition Finland is a vocal symphony for soprano, tenor and large orchestra set to the text of the early 19th century Russian Romantic poet Evgeny Baratynsky. The main idea behind this composition involves the combination of two contrasting approaches to musical composition: composing an abstract, independent musical work built on purely musical laws of structure and development and, on the other hand, writing a dramatic, programmatic work, the aim of which is to express emotions, to interpret and depict the subject matter of the literary text. The musical composition consists of six movements, following the poem’s six unequallength stanzas. Each movement is divided into a purely orchestral section and a vocalorchestral section, the latter featuring alternately the solo soprano and tenor. The work is written in the twelve-tone technique and involves references to a late Romantic musical language, emphasis on new textures and sonorities for the orchestra, occasional implications of tonality, and incorporation of serial rhythm in several of the work’s sections. The article gives a short account of Baratynsky’s biography and poetic writings and then proceeds to analyze the composition Finland in terms of both the large-scale structure and the details within the individual movements.

scholarly journals An image resource of subdivided Drosophila GAL4-driver expression patterns for neuron-level searches

2020 ◽  
Author(s):  
Geoffrey W. Meissner ◽  
Zachary Dorman ◽  
Aljoscha Nern ◽  
Kaitlyn Forster ◽  
Theresa Gibney ◽  
...  
Keyword(s):  
Light Microscopy ◽  
Large Scale ◽  
Expression Patterns ◽  
Identified Neurons ◽  
Gal4 Driver ◽  
Search Tool ◽  
Gal4 Expression ◽  
Central Nervous Systems ◽  
Confocal Images ◽  
The Individual

AbstractPrecise, repeatable genetic access to specific neurons via the GAL4/UAS system and related methods is a key advantage of Drosophila neuroscience. Neuronal targeting is typically documented using light microscopy of full GAL4 expression patterns, which mostly lack the single-cell resolution required for reliable cell type identification. Here we use stochastic GAL4 labeling with the MultiColor FlpOut approach to generate cellular resolution confocal images at large scale. We are releasing aligned images of 27,000 such adult central nervous systems.An anticipated use of this resource is to bridge the gap between electron microscopy-identified neurons and light microscopy-based intersectional genetic approaches such as the split-GAL4 system. Identifying the individual neurons that make up each GAL4 expression pattern improves the prediction of which GAL4 enhancer fragments best combine via split-GAL4 to target neurons of interest. To this end we have developed the NeuronBridge search tool, which matches these light microscope neuronal images to neurons in the recently published FlyEM hemibrain. This work thus provides a resource and search tool that will significantly enhance both the efficiency and efficacy of split-GAL4 targeting of EM-identified neurons and further advance Drosophila neuroscience.

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