scholarly journals Incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children: prospective population-based study

2019 ◽  
Vol 217 (1) ◽  
pp. 377-382
Author(s):  
Archana Basu ◽  
Dóra Körmendiné Farkas ◽  
Tammy Jiang ◽  
Karestan C. Koenen ◽  
Timothy L. Lash ◽  
...  
Keyword(s):  
Psychiatric Comorbidity ◽  
Stress Disorder ◽  
Adjustment Disorder ◽  
Population Based ◽  
Stress Disorders ◽  
Behavioural Disorder ◽  
Severe Stress ◽  
School Aged Children ◽  
Comparison Cohort ◽  
Danish School

BackgroundProspective population-based studies of psychiatric comorbidity following trauma and severe stress exposure in children are limited.AimsTo examine incident psychiatric comorbidity following stress disorder diagnoses in Danish school-aged children using Danish national healthcare system registries.MethodChildren (6–15 years of age) with a severe stress or adjustment disorder (ICD-10) between 1995 and 2011 (n = 11 292) were followed prospectively for an average of 5.8 years. Incident depressive, anxiety and behavioural disorder diagnoses were examined relative to an age- and gender-matched comparison cohort (n = 56 460) using Cox proportional hazards regression models. Effect modification by gender was examined through stratified analyses.ResultsAll severe stress and adjustment disorder diagnoses were associated with increased rates for all incident outcome disorders relative to the comparison cohort. For instance, adjustment disorders were associated with higher rates of incident depressive (rate ratio RR = 6.8; 95% CI 6.0–7.7), anxiety (RR = 5.3; 95% CI 4.5–6.4), and behavioural disorders (RR = 7.9; 95% CI 6.6–9.3). Similarly, PTSD was also associated with higher rates of depressive (RR = 7.4; 95% CI 4.2–13), anxiety (RR = 7.1; 95% CI 3.5–14) and behavioural disorder (RR = 4.9; 95% CI 2.3–11) diagnoses. There was no evidence of gender-related differences.ConclusionsStress disorders varying in symptom constellation and severity are associated with a range of incident psychiatric disorders in children. Transdiagnostic assessments within a longitudinal framework are needed to characterise the course of post-trauma or severe stressor psychopathology.

Exhaled breath condensate pH determinants in school‐aged children: a population‐based study

2021 ◽  
Author(s):  
Tiago Azenha Rama ◽  
Inês Paciência ◽  
João Cavaleiro Rufo ◽  
Diana Silva ◽  
Pedro Cunha ◽  
...  
Keyword(s):  
Exhaled Breath Condensate ◽  
Population Based ◽  
Exhaled Breath ◽  
Population Based Study ◽  
School Aged Children ◽  
Breath Condensate

scholarly journals Clinical and social factors associated with attention-deficit hyperactivity disorder medication use: population-based longitudinal study

2014 ◽  
Vol 205 (4) ◽  
pp. 291-297 ◽  
Author(s):  
Cédric Galéra ◽  
Jean-Baptiste Pingault ◽  
Grégory Michel ◽  
Manuel-Pierre Bouvard ◽  
Maria Melchior ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Psychiatric Comorbidity ◽  
Medication Use ◽  
Population Based ◽  
Social Characteristics ◽  
Adhd Medication ◽  
Social Variables ◽  
Hyperactivity Disorder ◽  
The Impact

BackgroundThe impact of longitudinal psychiatric comorbidity, parenting and social characteristics on attention-deficit hyperactivity disorder (ADHD) medication use is still poorly understood.AimsTo assess the baseline and longitudinal influences of behavioural and environmental factors on ADHD medication use.MethodSurvival regressions with time-dependent covariates were used to model data from a population-based longitudinal birth cohort. The sample (n = 1920) was assessed from age 5 months to 10 years. Measures of children's psychiatric symptoms, parenting practices and social characteristics available at baseline and during follow-up were used to identify individual and family-level features associated with subsequent use of ADHD medication.ResultsUse of ADHD medication ranged from 0.2 to 8.6% between ages 3.5 to 10 years. Hyperactivity–inattention was the strongest predictor of medication use (hazard ratio (HR) = 2.75, 95% CI 2.35–3.22). Among all social variables examined, low maternal education increased the likelihood of medication use (HR = 2.09, 95% CI 1.38–3.18) whereas immigrant status lowered this likelihood (HR = 0.40, 95% CI 0.17–0.92).ConclusionsBeyond ADHD symptoms, the likelihood of receiving ADHD medication is predicted by social variables and not by psychiatric comorbidity or by parenting. This emphasises the need to improve global interventions by offering the same therapeutic opportunities (including medication) as those received by the rest of the population to some subgroups (i.e. immigrants) and by diminishing possible unnecessary prescriptions.

Recent Trends in the Prescribing of ADHD Medications in Canadian Primary Care

2017 ◽  
Vol 24 (2) ◽  
pp. 301-308 ◽  
Author(s):  
Rachael Morkem ◽  
Scott Patten ◽  
John Queenan ◽  
David Barber
Keyword(s):  
Primary Care ◽  
Age Groups ◽  
Fold Increase ◽  
Population Based ◽  
Adhd Medication ◽  
Fourfold Increase ◽  
School Aged Children ◽  
Medication Prescribing ◽  
And Gender ◽  
Adhd Medications

Objective: The aim of this study was to describe the prevalence and incidence of ADHD medication prescribing, by age and gender, from 2005 to 2015 in Canadian primary care. Method: A population-based retrospective cohort study was conducted to evaluate the prescribing of ADHD medications between 2005 and 2015 using electronic medical record data. Yearly prevalence and incidence of ADHD medication prescribing were calculated for preschoolers (up to 5 years old), school-aged children (6-17 years old), and adults (18-65 years old) along with a description of the types of ADHD medications prescribed between 2005 and 2015. Results: Between 2005 and 2015, there was a 2.6-fold increase in the prevalence of ADHD medication prescribing to preschoolers, a 2.5-fold increase in school-aged children, and a fourfold increase in adults. There was a corresponding rise in incidence of prescribing although this rise was moderate and estimates were much lower compared with prevalence. The most commonly prescribed medication was Methylphenidate (65.0% of all ADHD medications prescribed). Conclusion: Although the prevalence of ADHD has remained stable over time, this study found an increase in the prescribing of ADHD medications in all age groups between 2005 and 2015. Incidence of new prescriptions was small relative to prevalence, suggesting that longer term treatments are being adopted.

scholarly journals Sleep problems increase the risk of musculoskeletal pain in boys but not girls: a prospective cohort study

2020 ◽  
Vol 179 (11) ◽  
pp. 1711-1719
Author(s):  
Alessandro Andreucci ◽  
Paul Campbell ◽  
Lisa K Mundy ◽  
Susan M Sawyer ◽  
Silja Kosola ◽  
...  
Keyword(s):  
Cohort Study ◽  
Musculoskeletal Pain ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Sleep Problems ◽  
Large Population ◽  
Population Based ◽  
School Aged Children ◽  
Increased Risk ◽  
One Year

Abstract Adults with sleep problems are at higher risk for onset of musculoskeletal pain, but the evidence is less clear for children. This prospective cohort study investigated whether children with sleep problems are at higher risk for onset of musculoskeletal pain and explored whether sex is a modifier of this association. In a prospective cohort study of Australian schoolchildren (n = 1239, mean age 9 years), the associations between sleep problems at baseline and new onset of both musculoskeletal pain and persistent musculoskeletal pain (pain lasting > 3 months) 1 year later were investigated using logistic regression. The potential modifying effect of sex was also assessed. One-year incidence proportion for musculoskeletal pain onset is 43% and 7% for persistent musculoskeletal pain. Sleep problems were associated with musculoskeletal pain onset and persistent musculoskeletal pain onset in boys, odds ratio 2.80 (95% CI 1.39, 5.62) and OR 3.70 (1.30, 10.54), respectively, but not girls OR 0.58 (0.28, 1.19) and OR 1.43 (0.41, 4.95), respectively. Conclusions: Rates of musculoskeletal pain are high in children. Boys with sleep problems are at greater risk of onset of musculoskeletal pain, but girls do not appear to have higher risk. Consideration of sleep health may help prevent persistent musculoskeletal pain in children. What is Known:• Sleep problems are associated with the onset of musculoskeletal pain in adults.• It is not clear if the association between sleep problems and the onset of musculoskeletal pain is present also in children and if sex plays a role in this association. What is New:• This is the first large population-based study that has prospectively investigated the relationship between sleep problems and onset of musculoskeletal pain in school-aged children.• Children, especially boys with sleep problems, were at increased risk for the development of persistent musculoskeletal pain.

scholarly journals Explanatory Style in Patients with Rheumatoid Arthritis: An Unrecognized Predictor of Mortality

2016 ◽  
Vol 44 (2) ◽  
pp. 170-173 ◽  
Author(s):  
Aaron D. Crowson ◽  
Robert C. Colligan ◽  
Eric L. Matteson ◽  
John M. Davis ◽  
Cynthia S. Crowson
Keyword(s):  
Rheumatoid Arthritis ◽  
Mortality Rate ◽  
Minnesota Multiphasic Personality Inventory ◽  
Explanatory Style ◽  
Population Based ◽  
Similar Magnitude ◽  
Risk Of Mortality ◽  
Increased Risk ◽  
Comparison Cohort ◽  
Pessimistic Explanatory Style

Objective.To determine whether pessimistic explanatory style altered the risk for and mortality of patients with rheumatoid arthritis (RA).Methods.The study included subjects from a population-based cohort with incident RA and a non-RA comparison cohort who completed the Minnesota Multiphasic Personality Inventory.Results.Among 148 RA and 135 non-RA subjects, pessimism was associated with development of rheumatoid factor (RF)–positive RA. Pessimism was associated with an increased risk of mortality [HR 2.88 with similar magnitude to RF+ (HR 2.28)].Conclusion.Pessimistic explanatory style was associated with an increased risk of developing RA and increased mortality rate in patients with RA.

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