Phenomenological differences appearing with repetitive behaviours in obsessive-compulsive disorder and Gilles de la Tourette's syndrome

1997 ◽  
Vol 170 (2) ◽  
pp. 140-145 ◽  
Author(s):  
Euripedes C. Miguel ◽  
Lee Baer ◽  
Barbara J. Coffey ◽  
Scott L. Rauch ◽  
Cary R. Savage ◽  
...  

BackgroundObsessive–compulsive disorder (OCD) is heterogeneous, with some forms related to Gilles de la Tourette's syndrome (GTS). This is a phenomenological study designed to investigate the nature of these possible OCD subtypes and the relationship between OCD and GTS.MethodWe evaluated 20 adult outpatients with OCD, 21 with GTS, and 20 with OCD plus GTS using a semi-structured interview designed to assess cognitive, sensory and autonomic phenomena preceding repetitive behaviours.ResultsMore cognitions and autonomic anxiety and fewer sensory phenomena were reported in OCD than in GTS. Like the GTS group, the OCD plus GTS group reported more sensory phenomena and fewer cognitions than the OCD group.ConclusionsThe presence or absence of cognitions, sensory phenomena, and autonomic anxiety distinguishes repetitive behaviours in patients with OCD from those with OCD plus GTS, and GTS. These subjective experiences may be useful in subtyping OCD and may represent valid predictors of prognosis and treatment response.

1994 ◽  
Vol 164 (6) ◽  
pp. 839-841 ◽  
Author(s):  
S. Fennig ◽  
S. Naisberg Fennig ◽  
M. Pato ◽  
A. Weitzman

A 14-year-old boy with obsessive–compulsive disorder (OCD) developed, under fluvoxamine treatment, acute symptoms of Tourette's syndrome (TS) with aggravation of the OCD. The TS symptoms did not respond to dopamine blockers and disappeared only after withdrawal of fluvoxamine. Readministration of fluvoxamine caused a re-emergence of the same symptoms.


1998 ◽  
Vol 10 (1) ◽  
pp. 116-117 ◽  
Author(s):  
Philip R. Saba ◽  
Khurshed Dastur ◽  
M. Reza Raji ◽  
Matcheri S. Keshavan ◽  
M. Ammar Katerji

2000 ◽  
Vol 2 (2) ◽  
pp. 125-139 ◽  
Author(s):  
Randall D. Buzan ◽  
Jay H. Shore ◽  
Christopher O’Brien ◽  
Christopher Schneck

1987 ◽  
Vol 151 (2) ◽  
pp. 195-199 ◽  
Author(s):  
D. E. Comings ◽  
B. G. Comings

We present 11 pedigrees in which a propositus with Gilles de la Tourette's syndrome had first or second-degree relatives with obsessive-compulsive behaviour or agoraphobia with panic attacks, but only partially expressed the TS gene (i.e. had only motor tics or vocal tics, or neither). Of 90 females over the age of 18 presenting with TS, or with motor or vocal tics alone, nine had severe agoraphobia with panic attacks. There may be genetic subtypes of both obsessive-compulsive disorder and agoraphobia with panic attacks that are due to partial expression of the TS gene.


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