The Incidence of Schizophrenia in Nottingham

1987 ◽  
Vol 151 (5) ◽  
pp. 619-626 ◽  
Author(s):  
J. E. Cooper ◽  
David Goodhead ◽  
Tom Craig ◽  
Michael Harris ◽  
John Howat ◽  
...  

Attempts were made to identify, and include in a two-year follow-up study, every patient living in the catchment area of the Mapperley group of psychiatric hospitals in Nottingham (population 390 000) who made their first-ever contact with the psychiatric services for a potentially schizophrenic illness during a two-year period (1 August 1978 to 31 July 1980). Screening was based upon symptoms rather than diagnosis, covering both in-patient and out-patient services; a consensus diagnosis using ICD-9 was made by the project team. The Nottingham Psychiatric Case Register was used in a retrospective Leakage Study which added nine cases to the 99 identified by the screening procedures. Incidence rates are given for both broad and narrow concepts of schizophrenia, and for DSM-III diagnosis. The Nottingham incidence rates are similar to those reported from other UK centres, and are near the middle of the range found in the other collaborating centres in the WHO study on Determinants of Outcome of Severe Mental Disorders. At entry to the study, 27 patients were out-patients, and 11 were never admitted to hospital at any time in the two-year follow-up period. Reasons for believing that the Nottingham administrative incidence may be close to the incidence in the community are discussed.

2014 ◽  
Vol 22 (9) ◽  
pp. 917-925 ◽  
Author(s):  
Rebecca S. Hock ◽  
Hochang Benjamin Lee ◽  
O. Joseph Bienvenu ◽  
Gerald Nestadt ◽  
Jack F. Samuels ◽  
...  

2018 ◽  
Vol 75 (12) ◽  
pp. 856-862 ◽  
Author(s):  
Liming Dong ◽  
William W Eaton ◽  
Adam P Spira ◽  
Jacqueline Agnew ◽  
Pamela J Surkan ◽  
...  

ObjectivesTo investigate the association between job strain and subsequent cognitive change over approximately 11 years, using data from the population-based Baltimore Epidemiologic Catchment Area follow-up study.MethodsThe sample ranged from 555 to 563 participants, depending on the outcome, who reported psychosocial characteristics corresponding to the full-time job they held at baseline (1993–1996). Overall cognitive performance was measured by the Mini-Mental State Examination (MMSE), and verbal memory was measured by the ImmediateWord Recall Task and Delayed Word Recall Task at baseline and follow-up (2004–2005). Multiple linear regression was used to examine the association between job strain and cognitive change, and inverse probability weighting was used to account for differential attrition.ResultsParticipants with high job demands (psychological or physical demands) and/or low job control had greater decrease in the MMSE and memory scores than those with low job demands and high job control. After adjustment for baseline outcome scores, age and sex, the greatest decrease was observed in participants with high job demands and low job control (MMSE: −0.24, 95% CI −0.36 to –0.11; verbal memory scores: −0.26, 95% CI −0.44 to –0.07). The differences were partially explained by sociodemographic characteristics, occupational prestige and health factors.ConclusionsFindings from this prospective study suggest that job strain is associated with and may be a potential modifiable risk factor for adverse cognitive outcomes.


2017 ◽  
Vol 136 (4) ◽  
pp. 400-408 ◽  
Author(s):  
R. H. Mørch ◽  
I. Dieset ◽  
A. Faerden ◽  
S. Hope ◽  
M. Aas ◽  
...  

2013 ◽  
Vol 47 (7) ◽  
pp. 851-857 ◽  
Author(s):  
Cédric Lemogne ◽  
Hermann Nabi ◽  
Maria Melchior ◽  
Marcel Goldberg ◽  
Frédéric Limosin ◽  
...  

1991 ◽  
Vol 159 (6) ◽  
pp. 811-816 ◽  
Author(s):  
Glynn Harrison ◽  
J. E. Cooper ◽  
Richard Gancarczyk

First-admission rates to psychiatric hospitals, and data from certain psychiatric case registers suggest that there may have been a substantial decline in the administrative incidence of schizophrenia in recent years. However, data from the Nottingham case register show that rates for first-onset schizophrenia remained stable between 1975 and 1987. It is suggested that variations in trends between different parts of the UK may be partly explained by differences in the proportion of migrants and their children in the population at risk.


2007 ◽  
Vol 173 (3) ◽  
pp. 168-174 ◽  
Author(s):  
Kokichi Arisawa ◽  
Hirokazu Uemura ◽  
Mineyoshi Hiyoshi ◽  
Satoru Dakeshita ◽  
Atsushi Kitayama ◽  
...  

2016 ◽  
Vol 22 (10) ◽  
pp. 1322-1331 ◽  
Author(s):  
Amanda M Mitchell ◽  
Patrick Pössel ◽  
Benjamin W Van Voorhees ◽  
William W Eaton

This study extended the literature by examining whether three profiles of depression predicted breast cancer status. In 1076 women of the Baltimore Epidemiologic Catchment Area study, depression status and hopelessness were measured at baseline and breast cancer status was ascertained 24 years later. Double depression, but not major depression or dysthymia, was associated with breast cancer. Hopelessness predicted fewer new cases of breast cancer. When double depression and hopelessness were simultaneously entered as predictors, the regression weights of both predictors increased. The role of severe and extended duration depression as well as possible explanations for unexpected findings are discussed.


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