Winter-Born v Summer-Born Schizophrenics

1987 ◽  
Vol 151 (4) ◽  
pp. 499-505 ◽  
Author(s):  
R. E. Kendell ◽  
I. W. Kemp
Keyword(s):  
General Population ◽  
Health Service ◽  
Sex Ratio ◽  
Age Of Onset ◽  
Psychiatric Inpatient ◽  
Data Set ◽  
Case Register ◽  
Large Populations ◽  
To Receive ◽  
First Admission

Data from two sources-the Edinburgh Psychiatric Case Register and the psychiatric inpatient records of the Scottish Health Service-were used to compare large populations of first-admission schizophrenics born in winter (January to March) and in summer (June to October). Parallel comparisons were carried out for affective psychoses. Comparison of the months of birth of the Scottish patients with those of the general population indicated that there was a 9% excess of schizophrenic births and a 3% excess of affective births in the first 3 months of the year. In the Edinburgh material, winter-born schizophrenics were more likely than the summer-born to receive a diagnosis of paranoid or schizoaffective schizophrenia and less likely to receive diagnoses other than schizophrenia on readmission, but neither of these differences emerged in the much larger Scottish material. There were no differences between winter-and summer-born schizophrenics in age of onset, sex ratio, or prognosis in either data set, nor were any significant differences found between winter- and summer-born affectives. We have therefore failed to demonstrate any convincing differences between winter-and summer-born schizophrenics.

Increased Occurrence of Schizophrenia and other Psychiatric Illnesses Among Twins

1996 ◽  
Vol 168 (6) ◽  
pp. 688-692 ◽  
Author(s):  
Ulla Kläning ◽  
Preben Bo Mortensen ◽  
Kirsten Ohm Kyvik
Keyword(s):  
General Population ◽  
Psychiatric Disorders ◽  
Record Linkage ◽  
Admission Rate ◽  
Case Register ◽  
Psychiatric Illnesses ◽  
Increased Risk ◽  
Methodological Problems ◽  
First Admission ◽  
Danish Twin

BackgroundWe wished to establish whether the occurrence of schizophrenia among twins is the same as among the general population.MethodThrough record linkage between the New Danish Twin Register and the Danish Psychiatric Case Register, the twins who have ever received a diagnosis of schizophrenia were identified. Through indirect standardisation for age, sex and dates of admission, the rate of first admission with diagnosis schizophrenia among twins is compared to the same rate in the general population.ResultsA 28% increase in the rate of first admissions for schizophrenia in twins compared to the general population was found. This is statistically significant and does not seem to be caused by any known methodological problems. Twins also had an increased first-admission rate of any psychiatric disorders.ConclusionThis increased risk does not seem to be explained by known methodological problems, but does differ from earlier studies.

Greater occurrence of schizophrenia in dizygotic but not monozygotic twins

1999 ◽  
Vol 175 (5) ◽  
pp. 407-409 ◽  
Author(s):  
Ulla Kläning
Keyword(s):  
General Population ◽  
Record Linkage ◽  
Monozygotic Twins ◽  
Young Cohort ◽  
Case Register ◽  
Dizygotic Twins ◽  
The Difference ◽  
Direction Opposite ◽  
First Admission ◽  
Danish Twin

BackgroundA previous study demonstrated a higher rate of first hospitalisation for schizophrenia in twins than in singletons.AimsTo compare the schizophrenia rates in monozygotic twins, dizygotic twins and the general population.MethodThrough record linkage between the Young Cohort of the Danish Twin Register and the Danish Psychiatric Case Register, the rate of schizophrenia in’ monozygotic and dizygotic twins and the rate in the general population were compared.ResultsThe rate of first admission to hospital for schizophrenia in dizygotic twins was 40% greater than that in the general population. The rate in monozygotic twins was not increased. The difference between the rates in mono- and dizygotic twins was statistically significant (P < 0.001)ConclusionsThis result is surprising and is in the direction opposite to that expected, suggesting new possibilities in the study of risk factors.

Suicide Ideation and Attempt in a Community Cohort of Urban Aboriginal Youth: A Cross-Sectional Study

Crisis ◽  
2013 ◽  
Vol 34 (4) ◽  
pp. 251-261 ◽  
Author(s):  
Joanne N. Luke ◽  
Ian P. Anderson ◽  
Graham J. Gee ◽  
Reg Thorpe ◽  
Kevin G. Rowley ◽  
...  
Keyword(s):  
Health Service ◽  
Indigenous People ◽  
Suicide Ideation ◽  
Aboriginal Health ◽  
Cross Sectional ◽  
Data Set ◽  
Indigenous Youth ◽  
Aboriginal Youth ◽  
Social Distress ◽  
Suicide Behavior

Background: There has been increasing attention over the last decade on the issue of indigenous youth suicide. A number of studies have documented the high prevalence of suicide behavior and mortality in Australia and internationally. However, no studies have focused on documenting the correlates of suicide behavior for indigenous youth in Australia. Aims: To examine the prevalence of suicide ideation and attempt and the associated factors for a community 1 The term ”community” refers specifically to Koori people affiliated with the Victorian Aboriginal Health Service. cohort of Koori 2 The term ”Koori” refers to indigenous people from the south-eastern region of Australia, including Melbourne. The term ”Aboriginal” has been used when referring to indigenous people from Australia. The term ”indigenous” has been used throughout this article when referring to the first people of a nation within an international context. (Aboriginal) youth. Method: Data were obtained from the Victorian Aboriginal Health Service (VAHS) Young People’s Project (YPP), a community initiated cross-sectional data set. In 1997/1998, self-reported data were collected for 172 Koori youth aged 12–26 years living in Melbourne, Australia. The data were analyzed to assess the prevalence of current suicide ideation and lifetime suicide attempt. Principal components analysis (PCA) was used to identify closely associated social, emotional, behavioral, and cultural variables at baseline and Cox regression modeling was then used to identify associations between PCA components and suicide ideation and attempt. Results: Ideation and attempt were reported at 23.3% and 24.4%, respectively. PCA yielded five components: (1) emotional distress, (2) social distress A, (3) social distress B, (4) cultural connection, (5) behavioral. All were positively and independently associated with suicide ideation and attempt, while cultural connection showed a negative association. Conclusions: Suicide ideation and attempt were common in this cross-section of indigenous youth with an unfavorable profile for the emotional, social, cultural, and behavioral factors.

scholarly journals Willingness of Greek general population to get a COVID-19 vaccine

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Georgia Kourlaba ◽  
Eleni Kourkouni ◽  
Stefania Maistreli ◽  
Christina-Grammatiki Tsopela ◽  
Nafsika-Maria Molocha ◽  
...  
Keyword(s):  
Public Health ◽  
General Population ◽  
Data Collection ◽  
Sample Size ◽  
Significant Proportion ◽  
Control Measures ◽  
Systematic Sampling ◽  
Computer Assisted ◽  
Public Health Officials ◽  
To Receive

Abstract Background Epidemiological data indicate that a large part of population needs to be vaccinated to achieve herd immunity. Hence, it is of high importance for public health officials to know whether people are going to get vaccinated for COVID-19. The objective of the present study was to examine the willingness of adult residents in Greece to receive a COVID-19 vaccine. Methods A cross-sectional was survey conducted among the adult general population of Greece between April 28, 2020 to May 03, 2020 (last week of lockdown), using a mixed methodology for data collection: Computer Assisted Telephone Interviewing (CATI) and Computer Assisted web Interviewing (CAWI). Using a sample size calculator, the target sample size was found to be around 1000 respondents. To ensure a nationally representative sample of the urban/rural population according to the Greek census 2011, a proportionate stratified by region systematic sampling procedure was used to recruit particpants. Data collection was guided through a structured questionnaire. Regarding willingness to COVID-19 vaccination, participants were asked to answer the following question: “If there was a vaccine available for the novel coronavirus, would you do it?” Results Of 1004 respondents only 57.7% stated that they are going to get vaccinated for COVID-19. Respondents aged > 65 years old, those who either themselves or a member of their household belonged to a vulnerable group, those believing that the COVID-19 virus was not developed in laboratories by humans, those believing that coronavirus is far more contagious and lethal compared to the H1N1 virus, and those believing that next waves are coming were statistically significantly more likely to be willing to get a COVID-19 vaccine. Higher knowledge score regarding symptoms, transmission routes and prevention and control measures against COVID-19 was significantly associated with higher willingness of respondents to get vaccinated. Conclusion A significant proportion of individuals in the general population are unwilling to receive a COVID-19 vaccine, stressing the need for public health officials to take immediate awareness-raising measures.

Do Developmental and Life-Course Theory Risk Factors Equally Predict Age of Onset Among Juvenile Sexual and Nonsexual Offenders?

Sexual Abuse ◽  
2018 ◽  
Vol 32 (1) ◽  
pp. 55-78 ◽  
Author(s):  
Melanie Rosa ◽  
Bryanna Fox ◽  
Wesley G. Jennings
Keyword(s):  
Risk Factors ◽  
Sex Offenders ◽  
Life Course ◽  
Age Of Onset ◽  
Juvenile Sex Offenders ◽  
Criminological Theory ◽  
Sex Offending ◽  
Data Set ◽  
Florida Department ◽  
Nonsexual Offenders

Previous empirical inquiries into the etiology of juvenile sex offending have been largely atheoretical. Consequently, a call for studies conducted utilizing developmental and life-course (DLC) criminological theory has been made to better understand the onset, development, risk, and protective factors of juvenile sex offending. Therefore, this study contributes to the discussion by testing key predictions proposed by the DLC framework regarding the theoretical correlates of early onset offending, as applied to juvenile sex offenders (JSOs) and juvenile nonsex offenders (JNSOs). Drawing on a data set of more than 64,000 youth referred to the Florida Department of Juvenile Justice, results indicate that although the number and severity of risk factors for early age of onset differ between the JSOs and JNSOs, the specific type of risk factors that emerged align with DLC theory predictions. The implications of these findings and contributions for DLC theory are also discussed.

scholarly journals Acceptance Rates and Beliefs toward COVID-19 Vaccination among the General Population of Pakistan: A Cross-Sectional Survey

2021 ◽  
Author(s):  
Farah Yasmin ◽  
Waleed Asghar ◽  
Maryam Salma Babar ◽  
Hiba Khan ◽  
Shoaib Ahmad ◽  
...  
Keyword(s):  
General Population ◽  
Cross Sectional Study ◽  
Vaccine Hesitancy ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Public ◽  
Polio Vaccination ◽  
Acceptance Rates ◽  
To Receive ◽  
Do So

Developing countries like Pakistan have previously suffered from barriers to acceptance of vaccination by the public because of financial and belief barriers. This study aims to explore these beliefs and highlight concerns regarding vaccine hesitancy in the general population of Pakistan since they are a hindrance to an effective coronavirus disease-19 (COVID-19) immunization in the country. A cross-sectional study was performed involving 1,778 participants from all four provinces of Pakistan. Results from the study showed more than half of the participants to be unsure of the safety (50%) and efficacy (51%) of the vaccine, whereas 42% were concerned about the side effects of the vaccine. About 72% of the respondents planned to get vaccinated, whereas 28% refused to do so. Internationally made imported vaccines were more trusted by the participants. Forty-four percent of the participants agreed to receive the vaccine upon recommendation from a physician. Lastly, participants who believed in the efficacy of the polio vaccination also considered the COVID-19 vaccine to be safe and effective.

scholarly journals On the correspondence of electrical and optical physiology in in vivo population-scale two-photon calcium imaging

2019 ◽  
Author(s):  
Peter Ledochowitsch ◽  
Lawrence Huang ◽  
Ulf Knoblich ◽  
Michael Oliver ◽  
Jerome Lecoq ◽  
...  
Keyword(s):  
Calcium Imaging ◽  
Biophysical Model ◽  
Data Set ◽  
Two Photon ◽  
Simultaneous Imaging ◽  
Fluorescence Measurements ◽  
Large Populations ◽  
Intractable Problem ◽  
Mouse Lines

AbstractMultiphoton calcium imaging is commonly used to monitor the spiking of large populations of neurons. Recovering action potentials from fluorescence necessitates calibration experiments, often with simultaneous imaging and cell-attached recording. Here we performed calibration for imaging conditions matching those of the Allen Brain Observatory. We developed a novel crowd-sourced, algorithmic approach to quality control. Our final data set was 50 recordings from 35 neurons in 3 mouse lines. Our calibration indicated that 3 or more spikes were required to produce consistent changes in fluorescence. Moreover, neither a simple linear model nor a more complex biophysical model accurately predicted fluorescence for small numbers of spikes (1-3). We observed increases in fluorescence corresponding to prolonged depolarizations, particularly in Emx1-IRES-Cre mouse line crosses. Our results indicate that deriving spike times from fluorescence measurements may be an intractable problem in some mouse lines.

Active monitoring of 12760 clozapine recipients in the UK and Ireland

1999 ◽  
Vol 175 (6) ◽  
pp. 576-580 ◽  
Author(s):  
Janet Munro ◽  
Desmond O'Sullivan ◽  
Christopher Andrews ◽  
Alejandro Arana ◽  
Ann Mortimer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Treatment Resistant ◽  
Active Monitoring ◽  
Case Register ◽  
Proportional Hazards Regression ◽  
Age Related ◽  
The Uk ◽  
To Receive

BackgroundPeople prescribed clozapine for treatment-resistant schizophrenia have mandatory haematological monitoring through a case register for identifying reversible neutropenia.AimsTo quantify risk factors for agranulocytosis in subjects receiving clozapine.MethodData from 12 760 subjects registered to receive clozapine from January 1990 to April 1997 were analysed. Risk factors for agranulocytosis were quantified using a Cox proportional-hazards regression analysis.ResultsThe risk for agranulocytosis in Asian subjects was 2.4 times that in Caucasians (P=0.03). There was an age-related increase in risk of 53% per decade (P=0.0001).ConclusionsThe case register yielded valuable information for guiding research into the causes of the haematological reactions.

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