Electrodermal Responding and Chlorpromazine Treatment in Schizophrenia

1987 ◽  
Vol 150 (6) ◽  
pp. 850-853 ◽  
Author(s):  
Stavroula Yannitsi ◽  
Aris Liakos ◽  
Yannis Papakostas
Keyword(s):  
Skin Conductance ◽  
Rating Scale ◽  
Skin Conductance Level ◽  
Brief Psychiatric Rating Scale ◽  
Skin Conductance Responses ◽  
Before And After ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale ◽  
Drug Free

Skin conductance level (SCL) and skin conductance responses (SCR) to a random series of tones were measured in 25 drug-free schizophrenic patients, 15 male and 10 female, before and after standard chlorpromazine treatment. The DSM-III diagnostic criteria were used for selecting subjects. Psychopathology was measured with the Brief Psychiatric Rating Scale. After treatment, patients showed an improved psychopathology and decreased SCL. There was a transition of patients to lower response categories: the number of responders decreased twice and the number of non-responders increased three times. Responders exhibited significantly higher SCL than non-responders and fast habituators were between the two groups.

Use of Animals in the Rehabilitation of Psychiatric Inpatients

1986 ◽  
Vol 58 (1) ◽  
pp. 63-66 ◽  
Author(s):  
Alan M. Beck ◽  
Louisa Seraydarian ◽  
G. Frederick Hunter
Keyword(s):  
Rating Scales ◽  
Rating Scale ◽  
Psychiatric Inpatients ◽  
Brief Psychiatric Rating Scale ◽  
Psychiatric Rating Scales ◽  
Before And After ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale ◽  
Activity Groups ◽  
The Impact

This study compared the impact of therapy and activity groups on two matched groups of 8 and 9 psychiatric inpatients. Daily sessions of the groups were held for 11 wk. in identical rooms except for the presence of caged finches in one of the rooms. The patients were evaluated before and after the sessions using standard psychiatric rating scales. The group who met in the room that contained animals (a cage with four finches) had significantly better attendance and participation and significantly improved in areas assessed by the Brief Psychiatric Rating Scale. Other positive trends indicated that the study should be replicated with larger samples and modified to increase interactions with the animals.

scholarly journals Correlation between Post-Acute Electroconvulsive Therapy Alpha-Band Spectrum Power Increase and Improvement of Psychiatric Symptoms

2021 ◽  
Vol 11 (12) ◽  
pp. 1315
Author(s):  
Hideyuki Iwanaga ◽  
Takefumi Ueno ◽  
Naoya Oribe ◽  
Manabu Hashimoto ◽  
Jun Nishimura ◽  
...  
Keyword(s):  
Electroconvulsive Therapy ◽  
Rating Scale ◽  
Psychiatric Symptoms ◽  
Spectral Power ◽  
Band Spectrum ◽  
Alpha Band ◽  
Brief Psychiatric Rating Scale ◽  
Before And After ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale

The results of quantitative electroencephalography (qEEG) studies on electroconvulsive therapy (ECT) have been inconsistent, and indicators of the efficacy of ECT have not been clearly identified. In this study, we examined whether qEEG could be used as an indicator of the effect of ECT by measuring it during the course of treatment. We analyzed qEEG data before and after acute-phase ECT in 18 patients with schizophrenia, mood disorders, and other psychiatric disorders. We processed the qEEG data and compared the spectral power between the data acquired before and after ECT. The spectral power increased significantly after ECT in the delta, theta, and alpha bands. There was a strong significant correlation between the increase in the spectral power of the alpha band after acute ECT and improvement in the Brief Psychiatric Rating Scale score. Our results suggest that an increase in the alpha-band spectral power may be useful as an objective indicator of the treatment effect of acute ECT.

Obsessive-compulsive symptoms induced by atypical anti-psychotics

2011 ◽  
Vol 26 (S2) ◽  
pp. 1220-1220
Author(s):  
A. Afkhamebrahimi
Keyword(s):  
Rating Scale ◽  
Obsessive Compulsive ◽  
Obsessive Compulsive Symptoms ◽  
Brief Psychiatric Rating Scale ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
The Mean ◽  
Psychiatric Rating Scale ◽  
In The Beginning ◽  
The Impact

ObjectiveThe impact of typical and atypical anti-psychotics on developing obsessive-compulsive symptoms in schizophrenic patients were investigated in this study.Materials and methods64 schizophrenic patients (32 cases in typical anti-psychotics group and 32 in atypical anti-psychotics group) participated in the study. All the patients first interviewed by SCID and then Yale Brown Obsessive-Compulsive Scale (Y-BOCS) and Brief psychiatric Rating Scale were administered in the beginning, 3 weeks and 6 weeks after treatment. The Data then transferred to SPSS program. for analysis.ResultsIn typical group the mean scores of Y-BOCS were 2.40, 2.30 and 2.18 in the beginning, 3 weeks and 6 weeks after treatment. In atypical group the mean scores of Y-BOCS were 4.12, 4.46 and 4.53 in three trials. There were no significant differences in the mean scores of Y-BOCS of two group in the beginning of the trial although a trend toward significance was observed but the differences between scores were significant in trial 2 (3 weeks) and trial 3 (6 weeks).DiscussionBased on this study and in line with previous studies, atypical anti-psychotics may induce obsessive compulsive symptoms (although mild) in patients with schizophrenia.

Baseline personality functioning correlates with 6 month outcome in schizophrenia

2003 ◽  
Vol 18 (3) ◽  
pp. 93-100 ◽  
Author(s):  
Secondo Fassino ◽  
Andrea Pierò ◽  
Elena Mongelli ◽  
Maria Luisa Caviglia ◽  
Nadia Delsedime ◽  
...  
Keyword(s):  
Personality Assessment ◽  
Multimodal Treatment ◽  
Rating Scale ◽  
Response To Treatment ◽  
Occupational Functioning ◽  
Personality Functioning ◽  
Brief Psychiatric Rating Scale ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale

AbstractObjectiveThe assessment of outcome in schizophrenic patients should consider both the response to treatment and the recovery of social skills. The aim was to evaluate the outcome and related psychostructural and clinical factors in schizophrenic patients after they underwent 6 months of residential multimodal treatment.MethodsFifty-two schizophrenic patients enrolled in a multimodal treatment program were included in the study. Symptomatology and social functioning were assessed with the Brief Psychiatric Rating Scale (BPRS) and the Social and Occupational Functioning Assessment Scale (SOFAS). The Karolinska Psychodynamic Profile (KAPP) was used for the psychostructural evaluation.ResultsAfter 6 months there was a significant improvement in the global scores of BPRS, SOFAS, and some areas of KAPP. The personality (KAPP) and social-occupational functioning (SOFAS) at baseline (T0) correlated with the global score of BPRS at 6 months (T6); moreover, SOFAS at T6 correlated with BPRS and KAPP at T0 and with the illness duration.ConclusionsThe better the personality functioning in schizophrenic patients the better seems to be the response to treatment, with regard to symptoms as well as rehabilitation. Personality assessment might be useful for the individualisation of therapies, even within the context of a standardised program.

Behavioural Family Management in Schizophrenia

1994 ◽  
Vol 164 (4) ◽  
pp. 501-506 ◽  
Author(s):  
Eugenia T. Randolph ◽  
Spencer Eth ◽  
Shirley M. Glynn ◽  
George G. Paz ◽  
Gregory B. Leong ◽  
...  
Keyword(s):  
Rating Scale ◽  
Health Clinic ◽  
Controlled Study ◽  
Veterans Administration ◽  
Family Management ◽  
First Year ◽  
Brief Psychiatric Rating Scale ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale

To test further the highly successful outcomes of a controlled study of in-home behavioural family management (BFM) for schizophrenic patients, a clinic-based version of this intervention was compared with customary care alone for 41 schizophrenic patients in a Veterans Administration (VA) mental health clinic. Monthly Brief Psychiatric Rating Scale (BPRS) ratings, conducted by clinic psychiatrists who were ‘blind’ to the patients' assignment, revealed that 3 (14%) patients who received behavioural family management as well as customary care, as compared with 11 (55%) patients who received customary care alone, had symptomatic exacerbations during the first year of treatment.

Correlation between Psychic and Somatic Symptoms and Vision in Aged Patients before and after a Cataract Operation

1991 ◽  
Vol 69 (3) ◽  
pp. 707-721 ◽  
Author(s):  
Ritva Fagerström
Keyword(s):  
Rating Scale ◽  
Somatic Symptoms ◽  
Cataract Operation ◽  
Old People ◽  
Aged Patients ◽  
Brief Psychiatric Rating Scale ◽  
Similar Association ◽  
Before And After ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale

The connection between psychic and somatic symptoms with vision was investigated by studying 100 cataract operation patients, aged 71 to 76 years, 25 of them being men and 75 women. The investigations were conducted one day before the operation and three months afterwards. The cataract operation restored sufficient acuity of vision for reading (minimum E-test value 0.40) to 79% of the old people. Psychic vsymptoms were tested with the Brief Psychiatric Rating Scale, Mini-Mult MMPI, and direct questions. Somatic symptoms were studied through questionnaires. Psychic symptoms showed a statistically significant correlation with vision before the cataract operation but not afterwards. Psychic symptoms increased with deterioration of the acuity of vision and diminished when the acuity of vision improved. Somatic symptoms did not show similar association with vision but the symptoms were significantly alleviated after the cataract operation. Restoration of vision through the cataract operation normalized the old people's psychic condition and reduced their somatic symptoms to correspond with their prior chronic diseases.

Negative and Depressive Symptoms in Schizophrenia

1989 ◽  
Vol 154 (2) ◽  
pp. 207-211 ◽  
Author(s):  
Parmanand Kulhara ◽  
Ajit Avasthi ◽  
Rakesh Chadda ◽  
Kishore Chandiramani ◽  
Surendra K. Mattoo ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Negative Symptoms ◽  
Rating Scale ◽  
Symptoms Of Depression ◽  
Brief Psychiatric Rating Scale ◽  
Significant Relationships ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale ◽  
Depressive Syndromes

Ninety-five schizophrenic patients were assessed using the Present State Examination, the Brief Psychiatric Rating Scale and the Scale for the Assessment of Negative Symptoms. Negative and depressive symptoms were frequent, and significant relationships among negative symptom complexes and depressive syndromes were noted. Retardation, lack of energy, slowness, and other symptoms of depression were significantly associated with the negative symptoms of schizophrenia. Depressed affect per se did not have a significant correlation with negative symptoms.

The Effect of Thioridazine on Prolactin Levels in Actutely Schizophrenic Patients: Challenge-Dose and Steady-State Levels

1980 ◽  
Vol 14 (2) ◽  
pp. 127-131 ◽  
Author(s):  
G. F. S. Johnson ◽  
G. E. Hunt
Keyword(s):  
Steady State ◽  
Rating Scale ◽  
Challenge Dose ◽  
Duration Of Treatment ◽  
Brief Psychiatric Rating Scale ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Steady State Levels ◽  
Male Patients ◽  
Psychiatric Rating Scale

Prolactin (PRL) levels in unmedicated male patients with acute schizophrenia were within normal range at baseline, increased five fold after a challenge dose of thioridazine, did not significantly increase further after therapeutic dosages, and remained elevated for the duration of treatment. The rise in PRL levels was significantly correlated with the steady-state plasma levels of thioridazine and/or mesoridazine. Baseline and challenge-dose PRL levels did not correlate with severity of symptoms as measured by the Brief Psychiatric Rating Scale, or predict response to thioridazine. Overall, there was a trend for the drug and PRL levels to increase very quickly and remain elevated while the clinical response was gradual over the four-week period. Clinically, it may be useful monitoring PRL levels, since the therapeutic dosage should usually be above the dosage required to produce maximal PRL levels.

The Neuroleptic Hypothesis: Study of the Covariation of Extrapyramidal and Therapeutic Drug Effects

1978 ◽  
Vol 133 (2) ◽  
pp. 169-175 ◽  
Author(s):  
M. Alpert ◽  
F. Diamond ◽  
J. Weisenfreund ◽  
E. Taleporos ◽  
A. J. Friedhoff
Keyword(s):  
Rating Scale ◽  
Drug Effects ◽  
Fixed Dose ◽  
Therapeutic Drug ◽  
Therapeutic Trial ◽  
Brief Psychiatric Rating Scale ◽  
Dopamine Hypothesis ◽  
Schizophrenic Patients ◽  
Psychiatric Rating ◽  
Psychiatric Rating Scale

SummaryA therapeutic trial with chlorpromazine was conducted with a homogeneous (for age and sex) group of recently admitted schizophrenic patients. Extrapyramidal effects were measured through quantitative analysis of digital tremor, after four days of fixed-dose treatment. Assessment of treatment efficacy was based on Brief Psychiatric Rating Scale ratings, done at the end of four weeks' treatment. Those patients whose tremor was least affected by drug were most likely to benefit from the treatment. Implications of this negative correlation for our understanding of the neuroleptic hypothesis and the closely associated dopamine hypothesis of schizophrenia are discussed.

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