The Clinical Picture of Bipolar Affective Disorder in its Depressed Phase

1982 ◽  
Vol 141 (6) ◽  
pp. 558-562 ◽  
Author(s):  
Ian F. Brockington ◽  
Edward Altman ◽  
Valerie Hillier ◽  
Herbert Y. Meltzer ◽  
Surinder Nand
Keyword(s):  
Affective Disorder ◽  
Mental State ◽  
Clinical Picture ◽  
Bipolar Affective Disorder ◽  
Large Series ◽  
Depressed Patients

SummaryUsing structured psychiatric interviews, we searched for differences between depressed patients with bipolar affective disorder, and with other types of depression. The patients were taken from 2 large series, collected in London and Chicago. Some differences were found, but few more than would be expected by chance, in view of the large number of variables examined. The possible reasons for this failure are discussed. They include contamination of the groups, and the insensitivity of structured mental state inventories.

Neuroleptic Malignant Syndrome and Risperidone: A Case Report

1996 ◽  
Vol 30 (3) ◽  
pp. 419-421 ◽  
Author(s):  
Richard J. Bonwick ◽  
Malcolm J. Hopwood ◽  
Philip L.R Morris
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Affective Disorder ◽  
Neuroleptic Malignant Syndrome ◽  
Clinical Picture ◽  
Bipolar Affective Disorder

Objective: To describe a case of neuroleptic malignant syndrome associated with risperidone. Clinical picture: An elderly patient with bipolar affective disorder presented with neuroleptic malignant syndrome and relapse of hypomania after commencing risperidone. Treatment: Risperidone was ceased and the patient monitored closely. Outcome: The symptoms of neuroleptic malignant syndrome were resolved. Conclusion: To our knowledge this is the first such case reported, and suggests that risperidone, like other neuroleptics, is associated with neuroleptic malignant syndrome.

scholarly journals MODERN APPROACHES TO THE TREATMENT OF PATIENTS WITH A PRIMARY EPISODE OF BIPOLAR AFFECTIVE DISORDER

2019 ◽  
Vol 85 (4) ◽  
pp. 55-61
Author(s):  
Yu.I. Mysula
Keyword(s):  
Quality Of Life ◽  
Affective Disorder ◽  
Mental State ◽  
Bipolar Affective Disorder ◽  
Depression Scale ◽  
Biomedical Ethics ◽  
Psychosocial Therapy ◽  
Traditional Scheme ◽  
Complete Clinical Remission

A comprehensive system of treatment and rehabilitation measures for the initial episode of bipolar affective disorder is proposed, which is implemented in three interrelated stages: a psychodiagnostic stage, which provides a comprehensive clinical and psychodiagnostic analysis to determine the clinical option; the stage of complex therapy, which involves the combination of psychopharmacology with normotymics, antidepressants, atypical neuroleptics with psychoeducation, compliance therapy, family therapy, work with comorbid mental and narcological pathology; and the stage of psychosocial rehabilitation and prevention, which includes supportive psychopharmacological therapy and psychosocial therapy and rehabilitation activities. We conducted a clinical psychodiagnostic examination of 88 patients with a primary episode of Bipolar Affective Disorder (PE BAD) who were treated at the Ternopil Regional Psychoneurological Hospital during the period 2011-2016 in compliance with the principles of biomedical ethics. The following groups were formed from them: 1) 34 patients with depressed variant of PE BAD, who received treatment according to the proposed scheme; 2) 33 patients with depressive variant of PE BAD who received treatment according to the traditional scheme; 3) 11 patients with a manic variant of PE BAD who received treatment according to the proposed scheme; 4) 10 patients with a manic variant of PE BAD who received treatment according to the traditional scheme. The results were compared in pairs in each of the clinical groups according to the clinical version of PE BAD. The evaluation was performed before the start of treatment and 6 months after the start of treatment in three main areas: dynamics of mental state (complete clinical remission, significant improvement of mental state, improvement of mental state, slight improvement of mental state); dynamics of changes in psycho-emotional state based on the results of evaluation using standardized psychodiagnostic tools (M. Hamilton Depression and Anxiety Scales, The Zung self-Rating Depression Scale, Bipolar Diagnostic Scale); the dynamics of quality of life indicators according to the Scale of Quality of Life Mezzich et al. in the adaptation of N.O. Maruta. The comparative analysis showed a higher effectiveness of the proposed therapy compared to the traditional relative clinical effect, normalization of the affective sphere and improvement of the quality of life of patients.

Effect of fasting during Ramadan on serum lithium level and mental state in bipolar affective disorder

2010 ◽  
Vol 25 (6) ◽  
pp. 323-327 ◽  
Author(s):  
Saeed Farooq ◽  
Zahid Nazar ◽  
Javed Akhter ◽  
Mohammad Irafn ◽  
Fazal Subhan ◽  
...  
Keyword(s):  
Affective Disorder ◽  
Mental State ◽  
Bipolar Affective Disorder ◽  
Lithium Level ◽  
Serum Lithium Level

scholarly journals Clinical picture and treatment of bipolar affective disorder in children and adolescents

2020 ◽  
Vol 54 (1) ◽  
pp. 35-50
Author(s):  
Lena Cichoń ◽  
Małgorzata Janas-Kozik ◽  
Andrzej Siwiec ◽  
Janusz Rybakowski
Keyword(s):  
Children And Adolescents ◽  
Affective Disorder ◽  
Clinical Picture ◽  
Bipolar Affective Disorder
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