scholarly journals Postconditioning effects following sevoflurane inhalational sedation in the ICU: a pilot study in cardiac surgery patients

Critical Care ◽  
2009 ◽  
Vol 13 (Suppl 1) ◽  
pp. P395
Author(s):  
K Röhm ◽  
J Mayer ◽  
J Boldt ◽  
S Suttner ◽  
S Piper
Keyword(s):  
Cardiac Surgery ◽  
Pilot Study ◽  
Inhalational Sedation

The Effects of Isoflurane, Sevoflurane, and Desflurane Anesthesia on Neurocognitive Outcome after Cardiac Surgery: A Pilot Study

2007 ◽  
Vol 10 (1) ◽  
pp. E36-E41 ◽  
Author(s):  
Meral Kanbak ◽  
Fatma Saricaoglu ◽  
Seda Akinci ◽  
Bahar Oc ◽  
Huriye Balci ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Pilot Study ◽  
Neurocognitive Outcome

scholarly journals Cerebral desaturation and delirium in patients having non-cardiac surgery - a pilot study

2021 ◽  
pp. 100162
Author(s):  
J.N. Harrison ◽  
J. Welch ◽  
C. Kailla ◽  
S. Huddart ◽  
E. Mathers ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Pilot Study ◽  
Cerebral Desaturation

Clinical application of a new ternary polymer, SEC-1 coat™, for pediatric cardiopulmonary bypass circuits: a prospective randomized pilot study

Perfusion ◽  
2020 ◽  
Vol 35 (8) ◽  
pp. 826-832
Author(s):  
Tomomi Hasegawa ◽  
Yoshihiro Oshima ◽  
Shinji Yokoyama ◽  
Asuka Akimoto ◽  
Yusuke Misaka ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Cardiopulmonary Bypass ◽  
Pilot Study ◽  
Interleukin 6 ◽  
Patient Characteristics ◽  
Serum Levels ◽  
Pediatric Cardiac Surgery ◽  
Interleukin 8 ◽  
Control Group ◽  
Platelet Counts

Objective: The use of biocompatible materials to reduce the systemic activation of inflammation and coagulation pathways is expanding rapidly. However, there have been few clinical studies of biocompatible circuits for pediatric cardiopulmonary bypass. This pilot study aimed to preliminarily evaluate the biocompatibility of SEC-1 coat™ (SEC) for cardiopulmonary bypass circuits in pediatric cardiac surgery. Methods: Twenty infants undergoing cardiac surgery for isolated ventricular septal defects at Kobe Children’s Hospital were assigned randomly to an SEC-coated (SEC group, n = 10) or heparin-coated (control group, n = 10) circuit. Perioperative data and the following markers were prospectively analyzed: platelet counts and interleukin-6, interleukin-8, C3a, β-thromboglobulin, and thrombin–antithrombin complex levels. Results: Neither patient characteristics nor postoperative clinical outcomes differed significantly between the SEC and control groups. Platelet counts markedly decreased during cardiopulmonary bypass in both groups, but were significantly better preserved in the SEC group. Fewer patients needed postoperative platelet transfusions in the SEC group. After cardiopulmonary bypass termination, serum levels of β-thromboglobulin and thrombin–antithrombin complex were significantly lower in the SEC than in the control group. Although the differences were not statistically significant, serum levels of interleukin-6, interleukin-8, and C3a had a tendency toward being lower in the SEC group, with good preservation of leukocyte counts, fibrinogen, and antithrombin III. Conclusion: SEC-1 coat™ for cardiopulmonary bypass circuits have good biocompatibility with regard to platelet preservation and in terms of attenuating inflammatory reaction or coagulation activation during pediatric cardiac surgery. It can be beneficial in pediatric as well as adult cardiac surgery.

Early discharge of cardiac surgery patients: A pilot study

1995 ◽  
Vol 4 (1) ◽  
pp. 40
Author(s):  
Jai Raman ◽  
Brian Buxton ◽  
Laurie Doolan ◽  
Kim Lumsden
Keyword(s):  
Cardiac Surgery ◽  
Pilot Study ◽  
Early Discharge

Urinary biomarkers to predict severe fluid overload after cardiac surgery: a pilot study

2021 ◽  
Author(s):  
Saban Elitok ◽  
Berend Isermann ◽  
Sabine Westphal ◽  
Prasad Devarajan ◽  
Christian Albert ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Cardiac Surgery ◽  
Intensive Care ◽  
Pilot Study ◽  
Intensive Care Unit Admission ◽  
Fluid Overload ◽  
Predictive Ability ◽  
Urinary Biomarkers ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Reactive Protein

Aim: To assess the predictive ability of urinary and plasma biomarkers and clinical routine parameters for subsequent severe fluid overload. Patients & methods: In a pilot study, we studied 100 adult patients after cardiac surgery. On intensive care unit admission, we measured biomarkers in urine (midkine, IL-6, neutrophil gelatinase-associated lipocalin [NGAL], hepcidin-25) and plasma (creatinine, urea, B-type natriuretic peptide, lactate, C-reactive protein, leukocytes, IL-6, NGAL, hepcidin-25) to predict postoperative severe fluid overload. Results: Urinary midkine, IL-6, NGAL and hepcidin-25 (all AUCs ≥0.79) predicted postoperative severe fluid overload (N = 5 patients). Urinary NGAL/hepcidin-25 ratio (AUC 0.867) predicted postoperative severe fluid overload after adjustment to EuroScore and need for norepinephrine on surgery day (odds ratio: 2.4). Conclusion: Urinary biomarkers on intensive care unit admission might be helpful to predict subsequent severe fluid overload after cardiac surgery.

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