scholarly journals Functional residual capacity measurement during mechanical ventilation in order to find the optimal positive end-expiratory pressure

Critical Care ◽  
2007 ◽  
Vol 11 (Suppl 2) ◽  
pp. P205
Author(s):  
I Bikker ◽  
D Reis Miranda ◽  
J Van Bommel ◽  
J Bakker ◽  
D Gommers
Keyword(s):  
Mechanical Ventilation ◽  
Functional Residual Capacity ◽  
Positive End Expiratory Pressure ◽  
Capacity Measurement ◽  
Residual Capacity

scholarly journals Accurate Measurement of Functional Residual Capacity and Oxygen Consumption of Patients on Mechanical Ventilation

1983 ◽  
Vol 11 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Kevin R. Cooper ◽  
Peter A. Boswell
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Oxygen Consumption ◽  
Functional Residual Capacity ◽  
Lung Model ◽  
Capacity Measurement ◽  
Icu Patients ◽  
Residual Capacity

We developed an apparatus and technique for the simultaneous measurement of functional residual capacity and oxygen uptake (V̇O2) for use in intensive care unit (ICU) patients. The accuracy of the functional residual capacity measurement was proven using an in vitro lung model and the reproducibility of this measurement was established by use in ICU patients. We tested the accuracy of the V̇O2 measurement in comparison with two other methods in common use among ICU patients and our method proved accurate. We conclude that this technique for measurement of functional residual capacity and V̇O2 is highly accurate and easily applied to patients on any mode of mechanical ventilation.

Positive end-expiratory pressure enhances development of a functional residual capacity in preterm rabbits ventilated from birth

2009 ◽  
Vol 106 (5) ◽  
pp. 1487-1493 ◽  
Author(s):  
Melissa L. Siew ◽  
Arjan B. te Pas ◽  
Megan J. Wallace ◽  
Marcus J. Kitchen ◽  
Robert A. Lewis ◽  
...  
Keyword(s):  
Functional Residual Capacity ◽  
Positive End Expiratory Pressure ◽  
Mechanically Ventilated ◽  
Very Preterm ◽  
Lung Aeration ◽  
X Ray Imaging ◽  
Airway Collapse ◽  
Distal Airway ◽  
Dead Space Volume ◽  
Residual Capacity

The factors regulating lung aeration and the initiation of pulmonary gas exchange at birth are largely unknown, particularly in infants born very preterm. As hydrostatic pressure gradients may play a role, we have examined the effect of a positive end-expiratory pressure (PEEP) on the spatial and temporal pattern of lung aeration in preterm rabbit pups mechanically ventilated from birth using simultaneous phase-contrast X-ray imaging and plethysmography. Preterm rabbit pups were delivered by caesarean section at 28 days of gestational age, anesthetized, intubated, and placed within a water-filled plethysmograph (head out). Pups were imaged as they were mechanically ventilated from birth with a PEEP of either 0 cmH2O or 5 cmH2O. The peak inflation pressure was held constant at 35 cmH2O. Without PEEP, gas only entered into the distal airways during inflation. The distal airways collapsed during expiration, and, as a result, the functional residual capacity (FRC) did not increase above the lung's anatomic dead space volume (2.5 ± 0.8 ml/kg). In contrast, ventilation with 5-cmH2O PEEP gradually increased aeration of the distal airways, which did not collapse at end expiration. The FRC achieved in pups ventilated with PEEP (19.9 ± 3.2 ml/kg) was significantly greater than in pups ventilated without PEEP (−2.3 ± 3.5 ml/kg). PEEP greatly facilitates aeration of the distal airways and the accumulation of FRC and prevents distal airway collapse at end expiration in very preterm rabbit pups mechanically ventilated from birth.

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