scholarly journals Assessing perforation of acute appendicitis using the delta neutrophil index reflecting the peripheral immature granulocyte count

Critical Care ◽  
2012 ◽  
Vol 16 (S1) ◽  
Author(s):  
NG Rhee ◽  
S Chung
Keyword(s):  
Acute Appendicitis ◽  
Granulocyte Count ◽  
Immature Granulocyte ◽  
Delta Neutrophil Index

scholarly journals Role of Manual Immature to Total Neutrophil (I/T) Ratio and Automated Immature Granulocyte Count (IGC) and Percentage (IG%) in the Early Diagnosis of Neonatal Sepsis

2021 ◽  
Author(s):  
Nalika Jayasekara ◽  
Chandima Kulathilake ◽  
Saraji Wijesekara ◽  
Indira Wijesiriwardena
Keyword(s):  
Neonatal Sepsis ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Full Blood Count ◽  
Cross Sectional ◽  
Granulocyte Count ◽  
Reactive Protein ◽  
Immature Granulocyte ◽  
Low Sensitivity

Abstract Background: The diagnosis of neonatal sepsis is challenging due to non-specific and subtle clinical features, low sensitivity and delay in routine laboratory tests. Current study was conducted to evaluate the role of manual immature/total (I/T) neutrophil ratio and automated immature granulocyte count (IGC) and immature granulocyte percentage (IG%) in the diagnosis of neonatal sepsis. Materials and Methods: An analytical cross-sectional study was done during a period of 6 months with a sample of 55 neonates admitted to Colombo South Teaching Hospital, Sri Lanka. A combination of clinical and laboratory parameters including full blood count, C-reactive protein and blood culture were used to identify the neonates with probable sepsis. The population was subcategorized into five (5) groups and manual immature/total neutrophil (I/T) ratio, immature granulocyte count (IGC) and immature granulocyte%(IG%) were done in each neonate. Results: The sensitivity of manual I/T ratio was 93.75% and negative predictive value (NPV) was 95.24%. The sensitivity for lower cut off values, IGC of 0.03x103/µL and IG% of 0.5% was 80% and 73.33% respectively. The NPV for above cut-off values were 25% and 0.5% respectively. The NPV was improved with higher cut-off values with 70.90% for IGC 0.3 and 70.59% for IG 3%, but sensitivity remained low with 40% and 33.33% respectively.Conclusion: Manual I/T ratio remains as a useful diagnostic tool in diagnosing and excluding neonatal sepsis with a very good sensitivity and NPV. However, further studies and well defined reference intervals are required in automated IGC and IG%.

scholarly journals Delta neutrophil index as an early predictor of acute appendicitis and acute complicated appendicitis in adults

2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Dong Hyuk Shin ◽  
Young Suk Cho ◽  
Gyu Chong Cho ◽  
Hee Cheol Ahn ◽  
Seung Min Park ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Complicated Appendicitis ◽  
Early Predictor ◽  
Delta Neutrophil Index
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