scholarly journals Hypoxia and oxidative stress in breast cancer Hypoxia signalling pathways

2001 ◽  
Vol 3 (5) ◽  
Author(s):  
Christopher W Pugh ◽  
Jonathan Gleadle ◽  
Patrick H Maxwell
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Signalling Pathways ◽  
And Oxidative Stress

scholarly journals Tamoxifen and oxidative stress: an overlooked connection

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Nermin S. Ahmed ◽  
Marek Samec ◽  
Alena Liskova ◽  
Peter Kubatka ◽  
Luciano Saso
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Gold Standard ◽  
Pharmacological Activities ◽  
Standard Drug ◽  
Menopausal Women ◽  
Wide Range ◽  
Post Menopausal ◽  
Apoptotic Effects ◽  
And Oxidative Stress

AbstractTamoxifen is the gold standard drug for the treatment of breast cancer in pre and post-menopausal women. Its journey from a failing contraceptive to a blockbuster is an example of pharmaceutical innovation challenges. Tamoxifen has a wide range of pharmacological activities; a drug that was initially thought to work via a simple Estrogen receptor (ER) mechanism was proven to mediate its activity through several non-ER mechanisms. Here in we review the previous literature describing ER and non-ER targets of tamoxifen, we highlighted the overlooked connection between tamoxifen, tamoxifen apoptotic effects and oxidative stress.

Antioxidant enzyme activities and oxidative stress in human breast cancer

1994 ◽  
Vol 120 (6) ◽  
pp. 374-377 ◽  
Author(s):  
K. Punnonen ◽  
M. Ahotupa ◽  
K. Asaishi ◽  
M. Hy�ty ◽  
R. Kudo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Human Breast Cancer ◽  
Antioxidant Enzyme Activities ◽  
Human Breast ◽  
And Oxidative Stress

scholarly journals Aucubin inhibited lipid accumulation and oxidative stress via Nrf2/ HO ‐1 and AMPK signalling pathways

2019 ◽  
Vol 23 (6) ◽  
pp. 4063-4075 ◽  
Author(s):  
Bingyu Shen ◽  
Chenxu Zhao ◽  
Yue Wang ◽  
Yi Peng ◽  
Jiaqi Cheng ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Accumulation ◽  
Signalling Pathways ◽  
And Oxidative Stress

scholarly journals Estrogen-induced breast cancer: Alterations in breast morphology and oxidative stress as a function of estrogen exposure

2008 ◽  
Vol 232 (1) ◽  
pp. 78-85 ◽  
Author(s):  
Sarah M. Mense ◽  
Fabrizio Remotti ◽  
Ashima Bhan ◽  
Bhupendra Singh ◽  
Mahmoud El-Tamer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Oxidative Stress ◽  
Estrogen Exposure ◽  
Breast Morphology ◽  
And Oxidative Stress
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