scholarly journals Central nervous system relapse in patients with breast cancer is associated with advanced stages, with the presence of circulating occult tumor cells and with the HER2/neu status

2006 ◽  
Vol 8 (4) ◽  
Author(s):  
John Souglakos ◽  
Lambros Vamvakas ◽  
Stella Apostolaki ◽  
Maria Perraki ◽  
Zacharenia Saridaki ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Tumor Cells ◽  
Central Nervous System Relapse ◽  
Occult Tumor ◽  
Advanced Stages ◽  
Occult Tumor Cells

scholarly journals Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer

2005 ◽  
Vol 118 (8) ◽  
pp. 2013-2019 ◽  
Author(s):  
Gro Wiedswang ◽  
Elin Borgen ◽  
Cecilie Schirmer ◽  
Rolf Kåresen ◽  
Gunnar Kvalheim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Bone Marrow ◽  
Tumor Cells ◽  
Clinical Significance ◽  
Occult Tumor ◽  
Occult Tumor Cells

Early Detection of Central Nervous System Relapse of Pediatric Leukemia with Measurement of Optic Nerve Sheath Diameter on MRI

2019 ◽  
Vol 15 (2) ◽  
pp. 237-241
Author(s):  
Taner Arpaci ◽  
Barbaros S. Karagun
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Optic Nerve ◽  
Early Detection ◽  
Optic Nerve Sheath Diameter ◽  
Central Nervous System Relapse ◽  
Mri Findings ◽  
Pediatric Leukemia ◽  
Optic Nerves ◽  
Cns Relapse

Background: Leukemia is the most common pediatric malignancy. Central Nervous System (CNS) is the most frequently involved extramedullary location at diagnosis and at relapse. </P><P> Objective: To determine if Magnetic Resonance Imaging (MRI) findings of optic nerves should contribute to early detection of CNS relapse in pediatric leukemia. Methods: Twenty patients (10 boys, 10 girls; mean age 8,3 years, range 4-16 years) with proven CNS relapse of leukemia followed up between 2009 and 2017 in our institution were included. Orbital MRI exams performed before and during CNS relapse were reviewed retrospectively. Forty optic nerves with Optic Nerve Sheaths (ONS) and Optic Nerve Heads (ONH) were evaluated on fat-suppressed T2-weighted TSE axial MR images. ONS diameter was measured from the point 10 mm posterior to the globe. ONS distension and ONH configuration were graded as 0, 1 and 2. Results: Before CNS relapse, right mean ONS diameter was 4.52 mm and left was 4.61 mm which were 5.68 mm and 5.66 mm respectively during CNS relapse showing a mean increase of 25% on right and 22% on left. During CNS relapse, ONS showed grade 0 distension in 15%, grade 1 in 60%, grade 2 in 25% and ONH demonstrated grade 0 configuration in 70%, grade 1 in 25% and grade 2 in 5% of the patients. Conclusion: MRI findings of optic nerves may contribute to diagnose CNS relapse by demonstrating elevated intracranial pressure in children with leukemia.

Seven cases of breast cancer recurrence limited to the central nervous system without other visceral metastases

Breast Cancer ◽  
2000 ◽  
Vol 7 (2) ◽  
pp. 153-156 ◽  
Author(s):  
Hisato Higashi ◽  
Takashi Fukutomi ◽  
Toru Watanabe ◽  
Isamu Adachi ◽  
Masaru Narabayashi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Central Nervous System ◽  
Nervous System ◽  
Cancer Recurrence ◽  
Breast Cancer Recurrence ◽  
Visceral Metastases ◽  
The Central Nervous System

Central nervous system relapse in acute promyelocytic leukemia

2002 ◽  
Vol 71 (1) ◽  
pp. 60-61 ◽  
Author(s):  
N. Colovic ◽  
A. Bogdanovic ◽  
P. Miljic ◽  
G. Jankovic ◽  
M. Colovic
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Acute Promyelocytic Leukemia ◽  
Promyelocytic Leukemia ◽  
Central Nervous System Relapse
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