scholarly journals Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: a longitudinal study

2007 ◽  
Vol 9 (4) ◽  
pp. R74 ◽  
Author(s):  
Jean-Pierre Pelletier ◽  
Jean-Pierre Raynauld ◽  
Marie-Josée Berthiaume ◽  
François Abram ◽  
Denis Choquette ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Risk Factors ◽  
Longitudinal Study ◽  
Magnetic Resonance ◽  
Knee Osteoarthritis ◽  
Weight Bearing ◽  
Cartilage Volume ◽  
Resonance Imaging ◽  
Quantitative Magnetic Resonance Imaging ◽  
Factors Associated

scholarly journals No loss of cartilage volume over three years in patients with knee osteoarthritis as assessed by magnetic resonance imaging

2002 ◽  
Vol 10 (12) ◽  
pp. 929-937 ◽  
Author(s):  
S.J. Gandy ◽  
P.A. Dieppe ◽  
M.C. Keen ◽  
R.A. Maciewicz ◽  
I. Watt ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Knee Osteoarthritis ◽  
Cartilage Volume ◽  
Resonance Imaging

scholarly journals Factors associated with hip cartilage volume measured by magnetic resonance imaging: The Tasmanian Older Adult Cohort Study

2005 ◽  
Vol 52 (4) ◽  
pp. 1069-1076 ◽  
Author(s):  
Guangju Zhai ◽  
Flavia Cicuttini ◽  
Velandai Srikanth ◽  
Helen Cooley ◽  
Changhai Ding ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cohort Study ◽  
Magnetic Resonance ◽  
Older Adult ◽  
Cartilage Volume ◽  
Resonance Imaging ◽  
Factors Associated ◽  
Hip Cartilage

scholarly journals Does cartilage volume or thickness distinguish knees with and without mild radiographic osteoarthritis? The Framingham Study

2009 ◽  
Vol 69 (01) ◽  
pp. 143-149 ◽  
Author(s):  
S Reichenbach ◽  
M Yang ◽  
F Eckstein ◽  
J Niu ◽  
D J Hunter ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Weight Bearing ◽  
Cartilage Damage ◽  
Three Dimensional ◽  
Cartilage Volume ◽  
Cartilage Thickness ◽  
Resonance Imaging ◽  
Radiographic Osteoarthritis ◽  
Study Participants

Objectives:To examine whether the quantity of cartilage or semiquantitative scores actually differ in knees with mild radiographic osteoarthritis compared with knees without osteoarthritis.Methods:Framingham Osteoarthritis Study participants had knee tibiofemoral magnetic resonance imaging-based measurements of cartilage. Using three-dimensional FLASH-water excitation sequences, cartilage volume, thickness and subregional cartilage thickness were measured and cartilage scored semiquantitatively (using the whole-organ magnetic resonance imaging score; WORMS). Using weight-bearing radiographs, mild osteoarthritis was defined as Kellgren/Lawrence (K/L) grade 2 and non-osteoarthritis as K/L grade 0. Differences between osteoarthritis and non-osteoarthritis knees in median cartilage measurements were tested using the Wilcoxon rank sum test.Results:Among 948 participants (one knee each), neither cartilage volume nor regional thickness were different in mild versus non-osteoarthritis knees. In mild osteoarthritis, cartilage erosions in focal areas were missed when cartilage was quantified over large regions such as the medial tibia. For some but not all subregions of cartilage, especially among men, cartilage thickness was lower (p<0.05) in mild osteoarthritis than non-osteoarthritis knees. Because semiquantitative scores captured focal erosions, median WORMS scores were higher in mild osteoarthritis than non-osteoarthritis (all p<0.05). In moderate/severe osteoarthritis (K/L grades 3 or 4), osteoarthritis knees had much lower cartilage thickness and higher WORMS scores than knees without osteoarthritis.Conclusions:In mild osteoarthritis, the focal loss of cartilage is missed by quantitative measures of cartilage volume or thickness over broad areas. Regional cartilage volume and thickness (eg, medial tibia) are not different in mild osteoarthritis versus non-osteoarthritis. Subregional thickness may be decreased in mild osteoarthritis. Semiquantitative scoring that assesses focal cartilage damage differentiates mild osteoarthritis from non-osteoarthritis.

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