Profile of Prescription Medication in a Pediatric Population

1988 ◽  
Vol 22 (12) ◽  
pp. 999-1002 ◽  
Author(s):  
Joseph O. Olubadewo ◽  
Ann Ikponmwamba
Keyword(s):  
Pediatric Population ◽  
Age Groups ◽  
Prescription Medication ◽  
Respiratory Disorder ◽  
Drug Usage ◽  
American Hospital ◽  
Adolescent Group ◽  
Younger Age ◽  
Age Dependent ◽  
Study Population

This retrospective study describes the prescription medication profile in an outpatient pediatric population (n = 510) retrieved from a hospital pharmacy computer file. The survey covers a three-month period. The study population included 281 male and 229 female patients divided according to age into three groups: infant (age 0–12 months); children (age 1–12 years); and adolescents (age 13–18 years). Medications prescribed were classified according to their pharmacotherapeutic properties as described in the American Hospital Formulary Service Drug Information 87. The findings pointed out that three pharmacotherapeutic categories (the antiinfective/chemotherapeutic, central nervous system (CNS), and respiratory agents) constituted 78.1 percent of the 1402 prescribed medications. The most frequently prescribed agents in each of these categories were, respectively, amoxicillin, aminophylline, and acetaminophen. These agents represent recent advances in drug usage because they became most frequently used only within the past ten years. The age-dependent medication profile indicated that there was a higher prescription rate of antiinfectives and respiratory disorder agents in the younger age groups; in the adolescent group CNS agents were more often prescribed.

scholarly journals Comparison of Prevalence of Periodontitis with Different Indices in Population of District Ghaziabad

2016 ◽  
Vol 04 (01) ◽  
pp. 023-030
Author(s):  
Vimal Kumar ◽  
Pallak Arora ◽  
Manish Khatri ◽  
Shivani Sharma ◽  
Sumit Malhotra ◽  
...  
Keyword(s):  
Periodontal Disease ◽  
Total Population ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sample Population ◽  
Age Group ◽  
Cross Sectional ◽  
Multi Stage ◽  
Younger Age ◽  
Study Population

Abstract Objective: To estimate the prevalence of periodontal disease with different indices. Methods & materials: The study population consisted of multistage stratified random sample of 1300 subjects from total population of district Ghaziabad. A cross-sectional study was conducted with multi stage stratified random sampling techniques to select the sample population. The subjects were divided into different age groups and the periodontal assessment was made on the basis of CPITN index and ESI Index. Results: The CPITN has shown to estimate incorrect periodontal disease prevalence because of its underestimation of the disease severity. A huge difference was noticed in the prevalence rate of periodontitis when subjects were examined with ESI index. Conclusion Periodontal disease was found to be highly prevalent in the study population and severity of disease increased with age. More number of subjects in younger age group were found to be healthy.

scholarly journals BRAF mutation testing of MSI CRCs in Lynch syndrome diagnostics: performance and efficiency according to patient’s age

2019 ◽  
Author(s):  
Hendrik Bläker ◽  
Saskia Haupt ◽  
Monika Morak ◽  
Elke Holinski-Feder ◽  
Alexander Arnold ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lynch Syndrome ◽  
Age Groups ◽  
The Elderly ◽  
Population Based ◽  
Mutation Testing ◽  
Younger Age ◽  
Age Dependent ◽  
Cost Calculations ◽  
Direct Referral

AbstractBackground and aimsBRAF V600E mutations have been reported to be associated with sporadic microsatellite-unstable (MSI) colorectal cancer (CRC), while rarely detected in CRCs of Lynch syndrome (LS) patients. Therefore, current international diagnostic guidelines recommend somatic BRAF mutation testing in MLH1-deficient MSI CRC patients to exclude LS. As sporadic BRAF-mutant MSI CRC is a disease of the elderly, while LS-associated CRC usually occurs at younger age, we hypothesized that the efficacy of BRAF testing in LS diagnostics may be age-dependent.MethodsWe systematically compared the prevalence of BRAF V600E mutations in LS-associated CRCs and MSI CRCs from population-based cohorts in different age groups as available from published studies, databases, and population-based patient cohorts. Cost calculations and sensitivity analysis of the BRAF testing for exclusion of LS was performed.ResultsAmong 969 MSI CRCs from LS mutation carriers from the literature and German HNPCC Consortium, 15 (1.6%, 95% CI: 0.9-2.6%) harbored BRAF mutations. 6/7 LS patients with BRAF-mutant CRC and reported age were <50 years. Among unselected MSI CRCs, 44.8% (339/756) harbored BRAF mutations, 92.3% (313/339) of which were detected in patients >60 years. In MSI CRC patients <50, BRAF mutations were detected only in 0.6% (2/339), and the inclusion of BRAF testing led to increased costs and higher risk of missing LS patients (1.2%) compared to other age groups.ConclusionBRAF testing in patients <50 years is cost-inefficient and carries the highest risk of missing LS patients among different age groups. We suggest direct referral of MSI CRC patients <50 years to genetic counseling without prior BRAF testing.

scholarly journals HEMORRHOIDS IN THE PEDIATRIC POPULATION: CLINICAL MANIFESTATIONS, DIAGNOSTICS AND TREATMENT

2019 ◽  
Vol 23 (3) ◽  
pp. 119-123
Author(s):  
Pyae Swe Aung ◽  
Viktoria V. Kholostova
Keyword(s):  
Surgical Treatment ◽  
Conservative Therapy ◽  
Ultrasound Examination ◽  
Pediatric Population ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Pain Syndrome ◽  
Effective Technique ◽  
Younger Age ◽  
Conservative And Surgical Treatment

Introduction. Hemorrhoids in childhood is a rare disease. That is why one can find only few works on this problem. Material and methods. 56 children with diagnosed hemorrhoids aged 4-18 were taken into the study. They had various clinical manifestations of the disease: perianal protrusion (76.4%), bleeding (82.3%), pain syndrome (71.5%). 51 patient (91.1%) had external hemorrhoids; 3 children (5.3%) - internal; 2 children (3.6%) - combined. Patients, by their clinical course, were distributed as follows: acute hemorrhoids - 33 children (58.9%), chronic one - 23 (41.1%). Ultrasound examination and sigmoidoscopy were used for diagnostics. Different curative techniques followed the developed curative algorithm: conservative therapy and surgery (open surgery and with the LigaSure apparatus) as well as sclerotherapy. Results. The most effective technique, having better cosmetic and clinical outcomes, was hemorrhoidectomy. Conservative treatment (more than 80%) can be a method of choice at early stages of the disease and at younger age groups. Outcomes after sclerotherapy are comparable with outcomes of conservative and surgical treatment. Sclerotherapy is recommended at the internal stages of hemorrhoids and in case of any contraindications to surgical treatment.

scholarly journals Hypothalamic hamartoma with gelastic seizures: a case report

2020 ◽  
Vol 7 (4) ◽  
pp. 961
Author(s):  
Zosangliani . ◽  
Avishek Datta ◽  
Rukuwe Thele ◽  
Bishal Gurung ◽  
T. Kambiakdik
Keyword(s):  
Pediatric Population ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Clonic Seizure ◽  
Tonic Clonic Seizure ◽  
Hypothalamic Hamartoma ◽  
Gelastic Seizures ◽  
Younger Age ◽  
Gelastic Seizure ◽  
Gelastic Epilepsy

Hypothalamic Hamartoma (HH) may have diverse clinical manifestations. Its hallmark association is with gelastic seizures. Gelastic epilepsy is characterized by episodes of loud, hollow, mirthless, stereo-typed, forced laughter. The patient may stare and giggle briefly without any other motor manifestations. Hypothalamic hamartoma is most often the cause of gelastic seizures. Here, authors report a case of gelastic seizure with hypothalamic hamartoma in a 14-month-old boy with an associated tonic clonic seizure.  This case highlights the possibility of underdiagnosed hypothalamic hamartoma in younger age groups among pediatric population.

scholarly journals Age and Sex-Related Associations between Marital Status, Physical Activity and TV Time

2022 ◽  
Vol 19 (1) ◽  
pp. 502
Author(s):  
Timothy Gustavo Cavazzotto ◽  
Natã Gomes de Lima Stavinski ◽  
Marcos Roberto Queiroga ◽  
Michael Pereira da Silva ◽  
Edilson Serpeloni Cyrino ◽  
...  
Keyword(s):  
Physical Activity ◽  
Marital Status ◽  
Health Effect ◽  
Age Groups ◽  
Population Based ◽  
Younger Age ◽  
Married Men ◽  
Age Dependent ◽  
Obesity Hypertension ◽  
Age And Sex

Marital status mediates an association between physical activity (PA) and TV time with health outcomes. However, population-based studies have revealed that the health effect of marriage or divorce is age-dependent and differs between women and men. The study aimed to identify the age and sex-related associations between marital status with PA and TV time. We used data from Vigitel, an annual telephone survey started in 2006 in Brazil. We applied a complex sample logistic regression model to estimate the odds for PA and TV time comparing marital statuses according to age and sex subgroups, independent of obesity, hypertension, diabetes, self-assessed poor health, and smoking. Our sample included 561,837 individuals from 18 to 99 years, with a TV time > 3 h/day (prevalence = 25.2%) and PA > 150 min/week (prevalence = 35%). Later, we divided our sample in seven age groups by marital status and sex. Compared to single individuals, married men and women were less likely to watch TV more than 3 h/day in participants >30 years old. When compared to single, married participants were less likely to do more than 150 min of PA/week at younger age groups. Married women older than 40 years were more likely to do more than 150 min of PA/week than the single ones, while there were no differences among married men by age group. In conclusion, our study suggests that the investments in public policies to encourage the practice of PA and reduction of TV time could be based on the marital status, sex, and age, prioritizing less active groups.

scholarly journals Age-dependent sex differences in calcium and phosphate homeostasis

2021 ◽  
Author(s):  
W N H Koek ◽  
N Campos-Obando ◽  
B C J van der Eerden ◽  
Y B De Rijke ◽  
Ma Ikram ◽  
...  
Keyword(s):  
Sex Differences ◽  
Serum Calcium ◽  
Age Groups ◽  
Serum Phosphate ◽  
Age Group ◽  
Phosphate Homeostasis ◽  
Younger Age ◽  
Age Dependent ◽  
Underlying Mechanisms ◽  
Group 1

Background: Sex differences in calcium and phosphate have been observed. We aimed to assess a relation with age. Methods: We used laboratory values of serum calcium, phosphate and albumin from three different samples (years 2005, 2010 and 2014) using the hospital information system of Erasmus MC, Rotterdam. The samples were divided into 3 age groups: 1-17, 18-44 and ≥45 years. Sex differences in calcium and phosphate were analyzed using ANCOVA, adjusting for age and serum albumin. Furthermore, sex by age interactions were determined and we analyzed differences between age groups stratified by sex Results: In all 3 samples there was a significant sex*age interaction for serum calcium and phosphate, whose levels were significantly higher in women compared to men above 45 years. No sex differences in the younger age groups were found. In men, serum calcium and phosphate levels were highest in the youngest age group compared to age groups 18-44 and ≥45 years. In women, serum calcium levels were also significantly higher in the age group 1-17 and the age group ≥45 years compared to the 18-44 years age group. In women, serum phosphate was different between the three different age groups with highest level in the group 1-17 years and lowest in the group 18-44 years. Conclusion: There are age dependent sex differences in serum calcium and phosphate. Furthermore, we found differences in serum calcium and phosphate between different age groups. Underlying mechanisms for these age- and sex differences are not yet fully elucidated.

Inequalities and Impact of Socioeconomic-Cultural Factors in Suicide Rates Across Italy

Crisis ◽  
2011 ◽  
Vol 32 (4) ◽  
pp. 178-185 ◽  
Author(s):  
Maurizio Pompili ◽  
Marco Innamorati ◽  
Monica Vichi ◽  
Maria Masocco ◽  
Nicola Vanacore ◽  
...  
Keyword(s):  
Suicide Rate ◽  
Age Groups ◽  
Premature Death ◽  
Mortality Rates ◽  
Mortality Data ◽  
Italian Population ◽  
Comprehensive Overview ◽  
Suicide Rates ◽  
Younger Age ◽  
Age And Sex

Background: Suicide is a major cause of premature death in Italy and occurs at different rates in the various regions. Aims: The aim of the present study was to provide a comprehensive overview of suicide in the Italian population aged 15 years and older for the years 1980–2006. Methods: Mortality data were extracted from the Italian Mortality Database. Results: Mortality rates for suicide in Italy reached a peak in 1985 and declined thereafter. The different patterns observed by age and sex indicated that the decrease in the suicide rate in Italy was initially the result of declining rates in those aged 45+ while, from 1997 on, the decrease was attributable principally to a reduction in suicide rates among the younger age groups. It was found that socioeconomic factors underlined major differences in the suicide rate across regions. Conclusions: The present study confirmed that suicide is a multifaceted phenomenon that may be determined by an array of factors. Suicide prevention should, therefore, be targeted to identifiable high-risk sociocultural groups in each country.

MONITORING RESULTS OF SAZAN (CYPRINUS CARPIO CARPIO LINNAEUS, 1758) POPULATION IN THE EASTERN PART OF THE TAGANROG BAY AND THE DON RIVER DELTA

2020 ◽  
Author(s):  
P.A. Balykin ◽  
◽  
A.V. Startsev ◽  
G.E. Guskov ◽  
A.S. Grin ◽  
...  
Keyword(s):  
Age Groups ◽  
Indirect Evidence ◽  
Parasite Fauna ◽  
River Delta ◽  
Weight Growth ◽  
Younger Age ◽  
Cyprinus Carpio Carpio ◽  
Don River ◽  
Taganrog Bay ◽  
Biological State

The materials for 2003-2018 on the biological state of sazan of the eastern part of the Taganrog Bay and the Don River delta were summarized. It has been shown that the catches of sazan in the study area consisted of more than half of the fish of younger age groups, the length of which was less than the commercial measure. The ratio of linear and weight growth of sazan is shifting towards a decrease in the mass of one-dimensional specimen, which is indirect evidence of the deterioration of the natural living conditions of semi-migratory fish. In 2019, the carp parasite fauna was represented by 7 species related to monogenes - 2 species, cestodes - 3 species, nematodes - 1 species, crustaceans - 1. The state of the sazan population needs further research.

COVID - 19 AND THE PROBLEM OF PERSONALITY

2020 ◽  
pp. 31-35
Author(s):  
Mazaeva N.A. ◽  
Golovina A.G.
Keyword(s):  
General Population ◽  
Age Groups ◽  
Personal Transformation ◽  
Personality Changes ◽  
Age Dependent

In order to determine possible trends in the dynamics and characterological structure of personality in the General population caused by the COVID-19 pandemic, which is a long-term strong stressful effect and clinically and psychopathologically comparable to chronic personality changes after experiencing a disaster, the conditions predisposing to personal transformation, including clinical and prognostic patterns, are analyzed. The age-dependent nature of these changes is shown, and a number of features identified for different age groups are discussed.

scholarly journals Five reasons COVID-19 is less severe in younger age groups

2020 ◽  
Author(s):  
Paul W Turke
Keyword(s):  
Life History ◽  
Life History Theory ◽  
Age Of Onset ◽  
Age Groups ◽  
Medical Community ◽  
System Function ◽  
The Third ◽  
Immune System Function ◽  
Age Related ◽  
Younger Age

Abstract The severity of COVID-19 is age-related, with the advantage going to younger age groups. Five reasons are presented. The first two are well-known, are being actively researched by the broader medical community, and therefore are discussed only briefly here. The third, fourth, and fifth reasons derive from evolutionary life history theory, and potentially fill gaps in current understanding of why and how young and old age groups respond differently to infection with SARS-CoV-2. Age of onset of generalized somatic aging, and the timing of its progression, are identified as important causes of these disparities, as are specific antagonistic pleiotropic tradeoffs in immune system function.

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