St. John’s Wort: A Systematic Review of Adverse Effects and Drug Interactions for the Consultation Psychiatrist

2003 ◽  
Vol 44 (4) ◽  
pp. 271-282 ◽  
Author(s):  
Paul Hammerness ◽  
Ethan Basch ◽  
Catherine Ulbricht ◽  
E.-P. Barrette ◽  
Ivo Foppa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Adverse Effects ◽  
Drug Interactions ◽  
St John’S Wort ◽  
St John's Wort

Natural health product–HIV drug interactions: a systematic review

2005 ◽  
Vol 16 (3) ◽  
pp. 181-186 ◽  
Author(s):  
Edward Mills ◽  
Victor Montori ◽  
Dan Perri ◽  
Elizabeth Phillips ◽  
Gideon Koren
Keyword(s):  
Systematic Review ◽  
Vitamin C ◽  
Drug Interactions ◽  
Herbal Medicines ◽  
Drug Level ◽  
Natural Health Products ◽  
Natural Health ◽  
Clinical Pharmacokinetics ◽  
St John’S Wort ◽  
St John's Wort

The use of natural health products (NHPs) within the HIV community is high. Several NHPs have demonstrated interactions with HIV medications that could contribute to drug failure. We aimed to conduct a systematic review of clinical trials examining NHP–HIV drug interactions and their methodological characteristics. We searched electronic databases and unpublished resources independently, in duplicate. Nine studies were identified, eight clinical pharmacokinetics trials and one population-pharmacokinetics trial. Investigators studied four different herbal medicines (St John's wort, garlic, goldenseal and milk thistle) and one vitamin (vitamin C). Significant interactions were observed with St John's wort, garlic and vitamin C. However, methodological challenges exist to making the results directly generalizable to patients. This review finds that important drug level changes exist when NHPs are combined with HIV medications. Considering patient values and the implications of these studies, further research is urgently required to determine the extent of interactions with other commonly used NHPs.

Adverse Effects of St. John’s Wort

2004 ◽  
Vol 65 (11) ◽  
pp. 1470-1479 ◽  
Author(s):  
Lars Knüppel ◽  
Klaus Linde
Keyword(s):  
Adverse Effects ◽  
St John’S Wort ◽  
St John's Wort

scholarly journals A systematic review of St. John’s wort for major depressive disorder

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Eric A. Apaydin ◽  
Alicia R. Maher ◽  
Roberta Shanman ◽  
Marika S. Booth ◽  
Jeremy N. V. Miles ◽  
...  
Keyword(s):  
Systematic Review ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Major Depressive ◽  
St John’S Wort ◽  
St John's Wort

scholarly journals Interaction of St John's wort with conventional drugs: systematic review of clinical trials

BMJ ◽  
2004 ◽  
Vol 329 (7456) ◽  
pp. 27-30 ◽  
Author(s):  
Edward Mills ◽  
Victor M Montori ◽  
Ping Wu ◽  
Keith Gallicano ◽  
Mike Clarke ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
St John’S Wort ◽  
St John's Wort

scholarly journals Clinical relevance of St. John's wort drug interactions revisited

2020 ◽  
Vol 177 (6) ◽  
pp. 1212-1226 ◽  
Author(s):  
Simon Nicolussi ◽  
Jürgen Drewe ◽  
Veronika Butterweck ◽  
Henriette E. Meyer zu Schwabedissen
Keyword(s):  
Drug Interactions ◽  
Clinical Relevance ◽  
St John’S Wort ◽  
St John's Wort

A systematic review and meta-analysis on the use of Hypericum perforatum (St. John's Wort) for pain conditions in dental practice

Homeopathy ◽  
2012 ◽  
Vol 101 (4) ◽  
pp. 204-210 ◽  
Author(s):  
Christa Raak ◽  
Arndt Büssing ◽  
Georg Gassmann ◽  
Katja Boehm ◽  
Thomas Ostermann
Keyword(s):  
Systematic Review ◽  
Hypericum Perforatum ◽  
Meta Analysis ◽  
Dental Practice ◽  
St John’S Wort ◽  
St John's Wort
Sign in / Sign up

Export Citation Format

Share Document