scholarly journals DNA methylome and transcriptome landscapes of cancer-associated fibroblasts reveal a smoking-associated malignancy index

2021 ◽  
Author(s):  
Sheng-Fang Su ◽  
Hao Ho ◽  
Jia-Hua Li ◽  
Ming-Fang Wu ◽  
Hsu-Chieh Wang ◽  
...  
Keyword(s):  
Cancer Associated Fibroblasts ◽  
Dna Methylome ◽  
Associated Malignancy

Pediatric Free-floating Anterior Chamber Cyst of the Iris Pigment Epithelium

2018 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Joshua S Agranat ◽  
Yoshihiro Yonekawa
Keyword(s):  
Optical Coherence Tomography ◽  
Anterior Chamber ◽  
Incidental Finding ◽  
Pigment Epithelium ◽  
Anterior Segment ◽  
Ultrasound Biomicroscopy ◽  
Optical Coherence ◽  
Visual Axis ◽  
Associated Malignancy ◽  
Anatomic Locations

Iris pigment epithelial (IPE) cysts are a subset of iris cysts that arise from the IPE. They are spontaneously erupting epithelial-lined cavities that are found in various anatomic locations of the iris, including the iris pupillary margin, midzone, periphery, and free floating in the vitreous or anterior chamber. We report the case of an asymptomatic 13-year-old boy with an incidental finding of a dislodged anterior chamber cyst diagnosed on routine examination. Modern multimodal image analysis of the cyst including anterior segment optical coherence tomography and ultrasound biomicroscopy (UBM) was utilized to characterize the microstructural anatomy of the lesion. The patient was managed conservatively without complications. Cysts of the IPE typically do not affect vision or ocular health and can be monitored and observed after ascertaining no associated malignancy. Initial diagnostic investigation can include UBM and anterior segment optical coherence tomography. Intervention should be reserved only for cases where the cyst growth leads to obstruction of the visual axis and/or other secondary complications.

768 THE ORIGIN AND FUNCTION OF CANCER-ASSOCIATED FIBROBLASTS IN COLORECTAL CARCINOGENESIS

2020 ◽  
Vol 158 (6) ◽  
pp. S-160
Author(s):  
Hiroki Kobayashi ◽  
Krystyna Gieniec ◽  
Tamsin Lannagan ◽  
Tongtong Wang ◽  
Samuel Asfaha ◽  
...  
Keyword(s):  
Colorectal Carcinogenesis ◽  
Cancer Associated Fibroblasts ◽  
And Function
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