Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms.

R R Henry; T P Ciaraldi; L Abrams-Carter; S Mudaliar; K S Park; S E Nikoulina

doi:10.1172/jci118906

Glycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms.

Journal of Clinical Investigation ◽

10.1172/jci118906 ◽

1996 ◽

Vol 98 (5) ◽

pp. 1231-1236 ◽

Cited By ~ 104

Author(s):

R R Henry ◽

T P Ciaraldi ◽

L Abrams-Carter ◽

S Mudaliar ◽

K S Park ◽

...

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Molecular Mechanisms ◽

Glycogen Synthase ◽

Muscle Cells ◽

Insulin Dependent Diabetes Mellitus ◽

Skeletal Muscle Cells ◽

Dependent Diabetes Mellitus ◽

Insulin Dependent ◽

Glycogen Synthase Activity

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Glucose transport in cultured human skeletal muscle cells. Regulation by insulin and glucose in nondiabetic and non-insulin-dependent diabetes mellitus subjects.

Journal of Clinical Investigation ◽

10.1172/jci118352 ◽

1995 ◽

Vol 96 (6) ◽

pp. 2820-2827 ◽

Cited By ~ 79

Author(s):

T P Ciaraldi ◽

L Abrams ◽

S Nikoulina ◽

S Mudaliar ◽

R R Henry

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Glucose Transport ◽

Human Skeletal Muscle ◽

Muscle Cells ◽

Insulin Dependent Diabetes Mellitus ◽

Skeletal Muscle Cells ◽

Dependent Diabetes Mellitus ◽

Human Skeletal Muscle Cells ◽

Insulin Dependent

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Insulin Receptor Function and Glycogen Synthase Activity in Skeletal Muscle Biopsies from Patients with Insulin-Dependent Diabetes Mellitus: Effects of Physical Training*

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jcem-69-1-158 ◽

1989 ◽

Vol 69 (1) ◽

pp. 158-164 ◽

Cited By ~ 34

Author(s):

JENS FRIIS BAK ◽

UFFE KJELDBERG JACOBSEN ◽

FRITZ SCHONAU JORGENSEN ◽

OLUF PEDERSEN

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Physical Training ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Dependent Diabetes Mellitus ◽

Receptor Function ◽

Insulin Dependent ◽

Glycogen Synthase Activity ◽

Muscle Biopsies

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Reduced glycogen synthase activity in skeletal muscle from obese patients with and without Type 2 (non-insulin-dependent) diabetes mellitus

Diabetologia ◽

10.1007/bf00405082 ◽

1991 ◽

Vol 34 (4) ◽

pp. 239-245 ◽

Cited By ~ 142

Author(s):

P. Damsbo ◽

A. Vaag ◽

O. Hother-Nielsen ◽

H. Beck-Nielsen

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Obese Patients ◽

Insulin Dependent ◽

Glycogen Synthase Activity

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Skeletal muscle glycogen synthase activity in subjects with non-insulin-dependent diabetes mellitus after glyburide therapy

Metabolism ◽

10.1016/0026-0495(90)90096-u ◽

1990 ◽

Vol 39 (11) ◽

pp. 1204-1210 ◽

Cited By ~ 15

Author(s):

Bulangu L. Nyomba ◽

Daniel Freymond ◽

Itamar Raz ◽

Karen Stone ◽

David M. Mott ◽

...

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Muscle Glycogen ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Skeletal Muscle Glycogen ◽

Insulin Dependent ◽

Glycogen Synthase Activity

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Hyperglycaemia compensates for the defects in insulin-mediated glucose metabolism and in the activation of glycogen synthase in the skeletal muscle of patients with Type 2 (non-insulin-dependent) diabetes mellitus

Diabetologia ◽

10.1007/bf00400856 ◽

1992 ◽

Vol 35 (1) ◽

pp. 80-88 ◽

Cited By ~ 33

Author(s):

A. Vaag ◽

P. Damsbo ◽

O. Hother-Nielsen ◽

H. Beck-Nielsen

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Glucose Metabolism ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Insulin Dependent

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Glutamine:fructose-6-phosphate amidotransferase activity in cultured human skeletal muscle cells: relationship to glucose disposal rate in control and non-insulin-dependent diabetes mellitus subjects and regulation by glucose and insulin.

Journal of Clinical Investigation ◽

10.1172/jci118538 ◽

1996 ◽

Vol 97 (5) ◽

pp. 1235-1241 ◽

Cited By ~ 58

Author(s):

M C Daniels ◽

T P Ciaraldi ◽

S Nikoulina ◽

R R Henry ◽

D A McClain

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Human Skeletal Muscle ◽

Muscle Cells ◽

Insulin Dependent Diabetes Mellitus ◽

Glucose Disposal ◽

Dependent Diabetes Mellitus ◽

Human Skeletal Muscle Cells ◽

Insulin Dependent ◽

Glucose Disposal Rate

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Multiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitus.

Journal of Clinical Investigation ◽

10.1172/jci115022 ◽

1991 ◽

Vol 87 (2) ◽

pp. 489-495 ◽

Cited By ~ 94

Author(s):

A W Thorburn ◽

B Gumbiner ◽

F Bulacan ◽

G Brechtel ◽

R R Henry

Keyword(s):

Diabetes Mellitus ◽

Muscle Glycogen ◽

Glycogen Synthase ◽

Glycogen Synthesis ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Multiple Defects ◽

Insulin Dependent ◽

Glycogen Synthase Activity

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Impaired activation of skeletal muscle glycogen synthase in non-insulin-dependent diabetes mellitus is unrelated to the degree of obesity

Metabolism ◽

10.1016/0026-0495(91)90106-7 ◽

1991 ◽

Vol 40 (3) ◽

pp. 252-260 ◽

Cited By ~ 31

Author(s):

Andrew B. Johnson ◽

Mary Argyraki ◽

Jonathan C. Thow ◽

Ian R. Jones ◽

David Broughton ◽

...

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Muscle Glycogen ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Skeletal Muscle Glycogen ◽

Insulin Dependent

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Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.

Journal of Clinical Investigation ◽

10.1172/jci116466 ◽

1993 ◽

Vol 91 (6) ◽

pp. 2342-2350 ◽

Cited By ~ 63

Author(s):

H Vestergaard ◽

S Lund ◽

F S Larsen ◽

O J Bjerrum ◽

O Pedersen

Keyword(s):

Diabetes Mellitus ◽

Skeletal Muscle ◽

Glycogen Synthase ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Mrna Levels ◽

Insulin Resistant ◽

Insulin Dependent

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Actions of novel antidiabetic thiazolidinedione, T-174, in animal models of non-insulin-dependent diabetes mellitus (NIDDM) and in cultured muscle cells

British Journal of Pharmacology ◽

10.1038/sj.bjp.0702066 ◽

1998 ◽

Vol 125 (3) ◽

pp. 429-436 ◽

Cited By ~ 28

Author(s):

Kenji Arakawa ◽

Tomomi Ishihara ◽

Masamichi Aoto ◽

Masanori Inamasu ◽

Akira Saito ◽

...

Keyword(s):

Diabetes Mellitus ◽

Animal Models ◽

Muscle Cells ◽

Insulin Dependent Diabetes Mellitus ◽

Insulin Dependent Diabetes ◽

Dependent Diabetes Mellitus ◽

Insulin Dependent

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