scholarly journals Live Borrelia burgdorferi preferentially activate interleukin-1 beta gene expression and protein synthesis over the interleukin-1 receptor antagonist.

1992 ◽  
Vol 90 (3) ◽  
pp. 906-912 ◽  
Author(s):  
L C Miller ◽  
S Isa ◽  
E Vannier ◽  
K Georgilis ◽  
A C Steere ◽  
...  
Keyword(s):  
Gene Expression ◽  
Protein Synthesis ◽  
Borrelia Burgdorferi ◽  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Interleukin 1 Receptor Antagonist ◽  
Beta Gene

Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: A possible interaction with polymorphisms in the interleukin 1 beta gene

Lung Cancer ◽  
2005 ◽  
Vol 50 (3) ◽  
pp. 285-290 ◽  
Author(s):  
Helge Lind ◽  
Shanbeh Zienolddiny ◽  
David Ryberg ◽  
Vidar Skaug ◽  
David H. Phillips ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Gene Polymorphism ◽  
Receptor Antagonist ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Interleukin 1 Receptor Antagonist ◽  
Beta Gene

scholarly journals Association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis: A literature review and meta-analysis

2020 ◽  
Vol 18 ◽  
pp. 205873922096239
Author(s):  
Jiaxuan Qin ◽  
Jinchun Xing ◽  
Zonglong Cai
Keyword(s):  
Literature Review ◽  
Receptor Antagonist ◽  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Case Control Studies ◽  
Interleukin 1 Receptor Antagonist ◽  
Different Populations ◽  
Beta Gene

Several case-control studies have been performed in different populations to uncover the association between interleukin-1 beta gene, interleukin-1 receptor antagonist gene polymorphisms and urolithiasis. Here we decided to perform a literature review and meta-analysis to further estimate it. A systematic search was conducted in PubMed, Embase, Cochrane, clinicaltrials.gov, CNKI databases. To pool the effect size, odds ratios and 95% confidence intervals were used. Finally, five articles were included. Our results of literature review suggested that IL1RN IVS2 VNTR might be associated with the risk of urolithiasis. However, the results of meta-analysis suggested that IL-1beta -511C>T, IL-1beta +3954C>T, and IL1RN IVS2 VNTR might not be associated with the risk of urolithiasis. There were not enough data to fully confirm this association and the results should be interpreted with caution.

scholarly journals Keratinocyte growth factor, tumor necrosis factor-alpha and interleukin-1 beta gene expression in cultured fibroblasts and keratinocytes from burned patients

2013 ◽  
Vol 28 (8) ◽  
pp. 551-558 ◽  
Author(s):  
Alfredo Gragnani ◽  
Bruno Rafael Müller ◽  
Ismael Dale Contrim Guerreiro da Silva ◽  
Samuel Marcos Ribeiro de Noronha ◽  
Lydia Masako Ferreira
Keyword(s):  
Gene Expression ◽  
Tumor Necrosis ◽  
Keratinocyte Growth Factor ◽  
Interleukin 1 ◽  
Interleukin 1 Beta ◽  
Necrosis Factor Alpha ◽  
Cultured Fibroblasts ◽  
Factor Alpha ◽  
Beta Gene ◽  
Necrosis Factor

scholarly journals Modulation of interleukin 1 beta gene expression by the immediate early genes of human cytomegalovirus.

1990 ◽  
Vol 85 (6) ◽  
pp. 1853-1857 ◽  
Author(s):  
G K Iwamoto ◽  
M M Monick ◽  
B D Clark ◽  
P E Auron ◽  
M F Stinski ◽  
...  
Keyword(s):  
Gene Expression ◽  
Human Cytomegalovirus ◽  
Interleukin 1 ◽  
Immediate Early Genes ◽  
Immediate Early ◽  
Interleukin 1 Beta ◽  
Early Genes ◽  
Beta Gene

scholarly journals A labile transcriptional repressor modulates endotoxin tolerance.

1994 ◽  
Vol 180 (6) ◽  
pp. 2269-2275 ◽  
Author(s):  
K E LaRue ◽  
C E McCall
Keyword(s):  
Gene Expression ◽  
Interleukin 1 ◽  
Endotoxin Tolerance ◽  
Potential Candidate ◽  
Interleukin 1 Beta ◽  
Transcription Inhibition ◽  
Cytokine Mrna ◽  
I Kappa B Alpha ◽  
Cellular Expression ◽  
Beta Gene

Tolerance to bacterial lipopolysaccharide (LPS, endotoxin) is an adaptive cellular process whereby exposure to endotoxin induces a subsequent hyporesponsive state characterized by decreased levels of LPS-induced cytokine mRNA and protein. We demonstrate, in a human promonocytic cell line, THP-1, that endotoxin tolerance is manifested by decreased LPS-induced interleukin 1 beta (IL-1 beta) transcription. Inhibition of protein synthesis reverses the tolerant phenotype by inducing transcription of IL-1 beta in the absence of a second stimulus. These results indicate that a labile protein contributes to the endotoxin-tolerant phenotype, and that this factor acts in a dominant repressive manner to inhibit the activity of existing transcription factors. We provide further data that cellular expression of I kappa B-alpha correlates with downregulated IL-1 beta gene expression during endotoxin tolerance, implicating I kappa B-alpha as a potential candidate for the labile repressor identified herein.

Sign in / Sign up

Export Citation Format

Share Document