scholarly journals Mechanism of the Redistribution of Renal Cortical Blood Flow during Hemorrhagic Hypotension in the Dog

1973 ◽  
Vol 52 (1) ◽  
pp. 39-47 ◽  
Author(s):  
Jay H. Stein ◽  
Sampanta Boonjarern ◽  
Richard C. Mauk ◽  
Thomas F. Ferris
1996 ◽  
Vol 37 (4) ◽  
pp. 587-590 ◽  
Author(s):  
Barry Högström ◽  
S.-O. Hietala ◽  
P. Rooth

1997 ◽  
Vol 80 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Holly R. Middlekauff ◽  
Egbert U. Nitzsche ◽  
Alison H. Nguyen ◽  
Carl K. Hoh ◽  
G. Gary Gibbs

1987 ◽  
Vol 252 (3) ◽  
pp. H521-H528 ◽  
Author(s):  
M. J. Breslow ◽  
D. A. Jordan ◽  
S. T. Thellman ◽  
R. J. Traystman

Hemorrhagic hypotension produces an increase in adrenal medullary blood flow and a decrease in adrenal cortical blood flow. To determine whether changes in adrenal blood flow during hemorrhage are neurally mediated, we compared blood flow responses following adrenal denervation (splanchnic nerve section) with changes in the contralateral, neurally intact adrenal. Blood pressure was reduced and maintained at 60 mmHg for 25 min by hemorrhage into a pressurized bottle system. Adrenal cortical blood flow decreased to 50% of control with hemorrhage in both the intact and denervated adrenal. Adrenal medullary blood flow increased to four times control levels at 15 and 25 min posthemorrhage in the intact adrenal, but was reduced to 50% of control at 3, 5, and 10 min posthemorrhage in the denervated adrenal. In a separate group of dogs, the greater splanchnic nerve on one side was electrically stimulated at 2, 5, or 15 Hz (n = 4 each group) for 40 min. Adrenal medullary blood flow increased 5- to 10-fold in the stimulated adrenal but was unchanged in the contralateral, nonstimulated adrenal. Adrenal cortical blood flow was not affected by nerve stimulation. We conclude that activity of the splanchnic nerve profoundly affects adrenal medullary vessels but not adrenal cortical vessels and mediates the observed increase in adrenal medullary blood flow during hemorrhagic hypotension.


Peptides ◽  
1998 ◽  
Vol 19 (2) ◽  
pp. 269-277 ◽  
Author(s):  
J.K.M. Coleman ◽  
L.T. Krebs ◽  
T.A. Hamilton ◽  
B. Ong ◽  
K.A. Lawrence ◽  
...  

1980 ◽  
Vol 29 (1) ◽  
pp. 57-62 ◽  
Author(s):  
James D. Sink ◽  
W. Randolph Chitwood ◽  
Ronald C. Hill ◽  
Andrew S. Wechsler

Sign in / Sign up

Export Citation Format

Share Document