scholarly journals Effect of mirtazapine on metabolism and energy substrate partitioning in healthy men

JCI Insight ◽  
2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Johannes M. Hennings ◽  
Sarah Heel ◽  
Katharina Lechner ◽  
Manfred Uhr ◽  
Tatjana Dose ◽  
...  
Keyword(s):  
Energy Substrate ◽  
Healthy Men ◽  
Substrate Partitioning

scholarly journals Insulin loading and some hormonal metabolic parameters in patients with the hypothalamic syndrome

1995 ◽  
Vol 41 (6) ◽  
pp. 16-19
Author(s):  
Ye. I. Sokolov ◽  
A. P. Zayev ◽  
T. P. Khovanskaya ◽  
S. A. Zhizhina ◽  
S. V. Petrin ◽  
...  
Keyword(s):  
Energy Consumption ◽  
Time Course ◽  
Regulatory Function ◽  
Oxygen Utilization ◽  
Energy Substrate ◽  
Healthy Men ◽  
Hypothalamic Syndrome ◽  
The Status ◽  
Insulin Test ◽  
Lactate Levels

Thirty-two men aged 18 to 28 with the hypothalamic syndrome and 64 age-matched healthy men were examined. Insulin test was carried out in 3 steps: before and 30 and 120 min after intravenous infusion of 0.15 U insulin per kg b.w. At all stages of insulin test, spirography parameters reflected the status of hypermetabolism connected with increased energy consumption and with a lesser efficacy of oxygen utilization. Measurements of hormones: ACTH, STH, and hydrocortisone in the blood and of adrenaline, noradrenaline, dopamine, and DOPA in the urine indicated a reduced regulatory function of the hypothalamo-pituitary-adrenal and sympathoadrenal systems in patients with the hypothalamic syndrome. Time course of IRI, glucose, pyruvate, and lactate levels in the blood plasma of patients with the hypothalamic syndrome was indicative of reduced insulin and glucose tolerance and of impaired utilization of glucose as an energy substrate.

Effects of a single bout of high-intensity interval exercise on C1q/TNF-related proteins

2019 ◽  
Vol 44 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Michihiro Kon ◽  
Yoshiko Ebi ◽  
Kohei Nakagaki
Keyword(s):  
Insulin Sensitivity ◽  
Body Mass ◽  
High Intensity ◽  
Interval Training ◽  
Energy Substrate ◽  
Healthy Men ◽  
Substrate Metabolism ◽  
Hmw Adiponectin ◽  
Single Bout ◽  
High Intensity Interval

High-intensity interval training (HIIT) is known to be an effective exercise training regimen to improve energy substrate metabolism and insulin sensitivity. However, the underlying mechanisms of improvement in insulin sensitivity due to HIIT have not yet been fully clarified. C1q/tumor necrosis factor-related protein (CTRP) 1 and CTRP9, which are adiponectin paralogs and novel adipokines, have favorable effects on energy substrate metabolism and insulin sensitivity. The purpose of this study was to investigate the effects of a single bout of HIIT on CTRP1 and CTRP9 secretions in healthy men. Eight healthy male subjects (mean ± SE: age, 23.4 ± 1.1 years; height, 172.1 ± 1.7 cm; body mass, 68.0 ± 2.0 kg; body mass index, 22.9 ± 0.5 kg/m2) participated in this study. They performed a single bout of HIIT consisted of four 30-s maximal cycling bouts with 4 min of rest between bouts using a cycle ergometer. Blood samples were collected before the exercise, at 0 (immediately after the exercise), 15, 30, and 120 min after the single bout of HIIT. Serum CTRP1, CTRP9, and high-molecular-weight (HMW) adiponectin concentrations were measured using enzyme-linked immunosolvent assay kits. CTRP1 concentration significantly increased at 120 min after the HIIT. CTRP9 concentration also significantly increased immediately after the single bout of HIIT. In contrast, there were no significant differences in HMW adiponectin concentration before and after the acute HIIT. These findings suggest that a single bout of HIIT may stimulate CTRP1 and CTRP9 secretions in healthy men.

scholarly journals Effects of endurance training on energy substrate partitioning during exercise in postmenopausal women

2008 ◽  
Vol 22 (S1) ◽  
Author(s):  
Zinta Arija Zarins ◽  
Jill A. Fattor ◽  
Gareth A. Wallis ◽  
Tamara L. Mau ◽  
Nastaran Faghihnia ◽  
...  
Keyword(s):  
Endurance Training ◽  
Postmenopausal Women ◽  
Energy Substrate ◽  
Substrate Partitioning

scholarly journals Energy Substrate Partitioning and Efficiency in Individuals With Atherogenic Lipoprotein Phenotype

Obesity ◽  
2011 ◽  
Vol 19 (7) ◽  
pp. 1360-1365 ◽  
Author(s):  
Nastaran Faghihnia ◽  
Patty W. Siri-Tarino ◽  
Ronald M. Krauss ◽  
George A. Brooks
Keyword(s):  
Energy Substrate ◽  
Atherogenic Lipoprotein ◽  
Substrate Partitioning ◽  
Atherogenic Lipoprotein Phenotype ◽  
Lipoprotein Phenotype

CFTR protein expression in healthy men spermatozoa is not correlated with fertilization rate of ova

2010 ◽  
Vol 34 (8) ◽  
pp. S12-S12
Author(s):  
Hong‑Ge Li ◽  
Chen Min Xu ◽  
Kun Li ◽  
Ya Ni ◽  
Wen‑Ying Chen ◽  
...  
Keyword(s):  
Protein Expression ◽  
Fertilization Rate ◽  
Healthy Men ◽  
Cftr Protein

Gene May Predict Aggression in Healthy Men

2006 ◽  
Vol 34 (10) ◽  
pp. 54
Author(s):  
PATRICE WENDLING
Keyword(s):  
Healthy Men

Variation in the Promoter Region of the β Fibrinogen Gene Is Associated with Plasma Fibrinogen Levels in Smokers and Non-Smokers

1991 ◽  
Vol 65 (05) ◽  
pp. 487-490 ◽  
Author(s):  
A E Thomas ◽  
F R Green ◽  
C H Kelleher ◽  
H C Wilkes ◽  
P J Brennan ◽  
...  
Keyword(s):  
Heart Disease ◽  
Promoter Region ◽  
Fragment Length Polymorphism ◽  
Fibrinogen Level ◽  
Plasma Fibrinogen ◽  
Plasma Fibrinogen Level ◽  
Healthy Men ◽  
History Of ◽  
General Practices ◽  
Restriction Fragment Length

SummaryWe investigated the association between fibrinogen levels and a HaeIII restriction fragment length polymorphism located at −453 bp from the start of transcription of the β fibrinogen gene. 292 healthy men aged 45 to 69 years, recruited from general practices throughout Britain, were studied. None had a history of ischaemic heart disease. 41.1% (120) were smokers and fibrinogen levels were higher in this group. The frequency of the noncutting allele (designated H2) was 0.19 and was the same in smokers and non-smokers. The H2 allele was associated with elevated levels of fibrinogen in both smokers and non-smokers and the effect of genotype was similar in both groups. After smoking, HaeIII genotype was the strongest predictor of fibrinogen levels and explained 3.1% of the variance in fibrinogen levels. These results confirm earlier studies that variation at the fibrinogen locus contributes to the between-individual differences in plasma fibrinogen level.

Sign in / Sign up

Export Citation Format

Share Document