scholarly journals A Rhesus Monkey With a Naturally Occurring Impairment of Disparity Vergence. II. Abnormal Near Response Cell Activity in the Supraoculomotor Area

2019 ◽  
Vol 60 (5) ◽  
pp. 1670
Author(s):  
Mark M. G. Walton ◽  
Adam Pallus ◽  
Michael Mustari
1986 ◽  
Vol 20 (4) ◽  
pp. 281-285 ◽  
Author(s):  
P. E. Fritz ◽  
J. G. Miller ◽  
M. Slayter ◽  
T. J. Smith

An aged wild-caught male rhesus monkey ( Macaca mulatta), maintained in a research facility for 10 years, developed bilateral pelvic limb paralysis without other signs of disease. Unresponsive to therapy, the monkey was killed and necropsied. Chronic inflammation with osteolysis of thoracic vertebrae 10-13 was observed. Pseudomonas pseudomallei was cultured and identified from cerebrospinal fluid obtained at the site of the thoracic lesion. This Gram-negative bacterium can cause infection in animals and man and may remain latent for years before the appearance of clinical signs.


2021 ◽  
Author(s):  
Adam K. Myers ◽  
Catherine F. Talbot ◽  
Laura A. Del Rosso ◽  
Alyssa C. Maness ◽  
Sierra M. V. Simmons ◽  
...  

The Lancet ◽  
1987 ◽  
Vol 330 (8571) ◽  
pp. 1338 ◽  
Author(s):  
D.G. Newell ◽  
M.J. Hudson ◽  
A. Baskerville

2019 ◽  
Vol 45 (4) ◽  
pp. 274-280
Author(s):  
Gabriela Fernandes ◽  
Stephen T. Vanyo ◽  
Shahad Bakheet Atiano Alsharif ◽  
Sebastiano Andreana ◽  
Michelle B. Visser ◽  
...  

Strontium is a naturally occurring alkaline earth metal that has been shown to be useful not only in the treatment and prevention of osteoporosis but also in the treatment of dentinal hypersensitivity in the oral cavity; strontium is also an effective cariostatic, antiplaque, antigingivitis agent. Relatively little is known, however, about the effects of strontium on gingival fibroblasts. The purpose of the present investigation was to conduct in vitro studies on the potential for strontium to positively affect the activity of these cells such that it might be effective in the enhancement of gingival attachment to surfaces, such as healing abutments in implants in the oral cavity. The results indicate that strontium added as strontium citrate (0.5–1.0 mM), both in the absence and presence of a healing abutment, increases human gingival cell activity and decreases apoptosis in these cells. Scanning electron microscopy studies also reveal that the addition of strontium increases attachment of gingival fibroblasts to the surfaces of healing abutments. These studies provide the basis for further investigations on the use of strontium in the prevention and treatment of peri-implantitis by maximizing the formation of a peri-implant soft-tissue barrier.


2001 ◽  
Vol 82 (3) ◽  
pp. 513-523 ◽  
Author(s):  
Alexandre Leitão ◽  
Clara Cartaxeiro ◽  
Ricardo Coelho ◽  
Benedita Cruz ◽  
R. M. E. Parkhouse ◽  
...  

African swine fever virus ASFV/NH/P68 is a naturally occurring, non-haemadsorbing and non-fatal isolate. Longitudinal clinical and immunological studies on 31 pigs inoculated oronasally or intramuscularly with this isolate defined two discrete groups of animals: those developing ASF chronic type lesions and those remaining asymptomatic. Animals developing lesions had viraemia and fever late after infection, NK activity levels close to that of control animals and high levels of anti-ASFV specific antibodies together with a marked hypergammaglobulinaemia involving IgG1, IgG2, IgM and IgA immunoglobulin isotypes. Pigs remaining asymptomatic after infection, on the other hand, did not have viraemia or fever after day 14 post-infection and had elevated NK cell activity, but normal plasma Ig concentrations and relatively low specific anti-virus antibody concentrations throughout the duration of the experiments. Importantly, the latter group of pigs virus were resistant to subsequent challenge with the highly virulent ASFV/L60 isolate and survived with no major changes in any of the parameters examined and referred to above. Finally, lymphoproliferative responses to the mitogens concanavalin A, phytohaemagglutinin and pokeweed mitogen were not depressed in either of the two clinically defined groups of pigs. Thus further studies with this infection model may provide new insights on mechanisms of protective immunity to ASFV.


2004 ◽  
Vol 92 (5) ◽  
pp. 2993-3013 ◽  
Author(s):  
Biao Tian ◽  
Josef P. Rauschecker

Single neurons were recorded from the lateral belt areas, anterolateral (AL), mediolateral (ML), and caudolateral (CL), of nonprimary auditory cortex in 4 adult rhesus monkeys under gas anesthesia, while the neurons were stimulated with frequency-modulated (FM) sweeps. Responses to FM sweeps, measured as the firing rate of the neurons, were invariably greater than those to tone bursts. In our stimuli, frequency changed linearly from low to high frequencies (FM direction “up”) or high to low frequencies (“down”) at varying speeds (FM rates). Neurons were highly selective to the rate and direction of the FM sweep. Significant differences were found between the 3 lateral belt areas with regard to their FM rate preferences: whereas neurons in ML responded to the whole range of FM rates, AL neurons responded better to slower FM rates in the range of naturally occurring communication sounds. CL neurons generally responded best to fast FM rates at a speed of several hundred Hz/ms, which have the broadest frequency spectrum. These selectivities are consistent with a role of AL in the decoding of communication sounds and of CL in the localization of sounds, which works best with broader bandwidths. Together, the results support the hypothesis of parallel streams for the processing of different aspects of sounds, including auditory objects and auditory space.


Nature ◽  
1994 ◽  
Vol 369 (6479) ◽  
pp. 403-407 ◽  
Author(s):  
Paul Klenerman ◽  
Sarah Rowland-Jones ◽  
Steve McAdam ◽  
Jon Edwards ◽  
Susan Daenke ◽  
...  

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