Processing of Frequency-Modulated Sounds in the Lateral Auditory Belt Cortex of the Rhesus Monkey

2004 ◽  
Vol 92 (5) ◽  
pp. 2993-3013 ◽  
Author(s):  
Biao Tian ◽  
Josef P. Rauschecker
Keyword(s):  
Rhesus Monkey ◽  
Rhesus Monkeys ◽  
Single Neurons ◽  
Low Frequencies ◽  
Auditory Space ◽  
High Frequencies ◽  
Naturally Occurring ◽  
Parallel Streams ◽  
Gas Anesthesia

Single neurons were recorded from the lateral belt areas, anterolateral (AL), mediolateral (ML), and caudolateral (CL), of nonprimary auditory cortex in 4 adult rhesus monkeys under gas anesthesia, while the neurons were stimulated with frequency-modulated (FM) sweeps. Responses to FM sweeps, measured as the firing rate of the neurons, were invariably greater than those to tone bursts. In our stimuli, frequency changed linearly from low to high frequencies (FM direction “up”) or high to low frequencies (“down”) at varying speeds (FM rates). Neurons were highly selective to the rate and direction of the FM sweep. Significant differences were found between the 3 lateral belt areas with regard to their FM rate preferences: whereas neurons in ML responded to the whole range of FM rates, AL neurons responded better to slower FM rates in the range of naturally occurring communication sounds. CL neurons generally responded best to fast FM rates at a speed of several hundred Hz/ms, which have the broadest frequency spectrum. These selectivities are consistent with a role of AL in the decoding of communication sounds and of CL in the localization of sounds, which works best with broader bandwidths. Together, the results support the hypothesis of parallel streams for the processing of different aspects of sounds, including auditory objects and auditory space.

Social Roles in a Rhesus Monkey Group

Behaviour ◽  
1966 ◽  
Vol 26 (1-2) ◽  
pp. 91-104 ◽  
Author(s):  
Lawrence G. Sharpe ◽  
Irwin S. Bernstein
Keyword(s):  
Rhesus Monkey ◽  
Rhesus Monkeys ◽  
Quantitative Data ◽  
Activity Patterns ◽  
Behavior Patterns ◽  
Dominant Male ◽  
Specific Behavior ◽  
Natural Group ◽  
Subgroup Classification

AbstractA group of eleven rhesus monkeys selected to approximate a small natural group were allowed to establish a social organization and to live with minimal disturbance in a specially designed compound. Observations were made on a variety of social and individual activities with some manipulation of feeding used to get at specific behavior patterns. Quantitative data on the frequency of activities for each member of the group was obtained. Individual animals were found to fall into subgroup classification in terms of activity patterns observed. This role differentiation was consistent despite minor modifications observed in some individuals. The subgroups correspond by the large to morphological divisions of size and sex, but status also contributed to the differentiation of roles. The role of the dominant male was analyzed in detail and found to supercede that of simple preempting of incentives. Less elaborate analyses were made for other clearly differentiated roles in the group.

scholarly journals Induction of Ty Recombination in Yeast by cDNA and Transcription: Role of the RAD1 and RAD52 Genes

Genetics ◽  
1996 ◽  
Vol 144 (3) ◽  
pp. 947-955 ◽  
Author(s):  
Yael Nevo-Caspi ◽  
Martin Kupiec
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Repeated Sequences ◽  
Gene Products ◽  
Yeast Saccharomyces Cerevisiae ◽  
Low Frequencies ◽  
High Frequencies ◽  
Ectopic Recombination ◽  
Gal1 Promoter ◽  
Recombination Gene

Abstract In the yeast Saccharomyces cerevisiae ectopic recombination has been shown to occur at high frequencies for artificially created repeats, but at relatively low frequencies for a natural family of repeated sequences, the Ty family. Little is known about the mechanism(s) that prevent recombination between repeated sequences. We have previously shown that nonreciprocal recombination (gene conversion) of a genetically marked Ty can be induced either by the presence of high levels of Ty cDNA or by transcription of the marked Ty from a GAL1 promoter. These two kinds of induction act in a synergistic manner. To further characterize these two kinds of Ty recombination, we have investigated the role played by the RkD52 and RAD1 genes. We have found that the RAD52 and RAD1 gene products are essential to carry out transcription-induced Ty conversion whereas cDNA-mediated conversion can take place in their absence.

scholarly journals Register impacts perceptual consonance through roughness and sharpness

2021 ◽  
Author(s):  
Tuomas Eerola ◽  
Imre Lahdelma
Keyword(s):  
Past Research ◽  
Cultural Factors ◽  
Online Experiment ◽  
Low Frequencies ◽  
High Frequencies ◽  
Limited Frequency ◽  
The Impact ◽  
Selection Of ◽  
Consonance And Dissonance

AbstractThe perception of consonance and dissonance in intervals and chords is influenced by psychoacoustic and cultural factors. Past research has provided conflicting observations about the role of frequency in assessing musical consonance that may stem from comparisons of limited frequency bands without much theorizing or modeling. Here we examine the effect of register on perceptual consonance of chords. Based on two acoustic principles, we predict a decrease in consonance at low frequencies (roughness) and a decrease of consonance at high frequencies (sharpness). Due to these two separate principles, we hypothesize that frequency will have a curvilinear impact on consonance. A selection of tetrads varying in consonance were presented in seven registers spanning 30 to 2600 Hz. Fifty-five participants rated the stimuli in an online experiment. The effect of register on consonance ratings was clear and largely according to the predictions; The low registers impacted consonance negatively and the highest two registers also received significantly lower consonance ratings than the middle registers. The impact of register on consonance could be accurately described with a cubic relationship. Overall, the influence of roughness was more pronounced on consonance ratings than sharpness. Together, these findings clarify previous empirical efforts to model the effect of frequency on consonance through basic acoustic principles. They further suggest that a credible account of consonance and dissonance in music needs to incorporate register.

A Search for Chaotic Behavior in Stratospheric Variability: Comparison between the Northern and Southern Hemispheres

2014 ◽  
Vol 71 (12) ◽  
pp. 4611-4620 ◽  
Author(s):  
Gualtiero Badin ◽  
Daniela I.V. Domeisen
Keyword(s):  
Time Series ◽  
Gaussian Distribution ◽  
Chaotic Behavior ◽  
Low Frequencies ◽  
Large Variability ◽  
High Frequencies ◽  
Low Dimensional ◽  
Northern And Southern Hemispheres ◽  
Stratospheric Variability

Abstract Southern Hemisphere (SH) stratospheric variability is investigated with respect to chaotic behavior using time series from three different variables extracted from four different reanalysis products. The results are compared with the same analysis applied to the Northern Hemisphere (NH). The probability density functions (PDFs) for the SH show persistent deviations from a Gaussian distribution. The variability is given by white spectra for low frequencies, a slope of −1 for intermediate frequencies, and −3 slopes for high frequencies. Considering the time series for winter and summer separately, PDFs show a Gaussian distribution and the variability spectra change their slopes, indicating the role of the transition between winter and summer variability in shaping the time series. The correlation (D2) and the Kaplan–Yorke (DKY) dimensions are estimated. A finite value of the dimensions can be computed for each variable and data product, except for the NCEP zonal-mean zonal wind and temperature data, which violate the requirement D2 ≤ DKY, possibly owing to the presence of spurious trends and inconsistencies in the data. The value of D2 ranges between 2.6 and 3.9, while DKY ranges between 3.0 and 4.5. The results show that both D2 and DKY display large variability in their values both for different datasets and for different variables within the same dataset. The variability of the values of D2 and DKY thus leaves open the question about the existence of a low-dimensional attractor or if the finite dimensions of the system are the result of the projection of a larger attractor in a low-dimensional embedding space.

The Growth of Herpesvirus mulatto in Human Fibroblast

1974 ◽  
Vol 32 ◽  
pp. 244-245
Author(s):  
Glennelle Washington ◽  
Philip P. McGrath ◽  
Peter R. Graze ◽  
Ivor Royston
Keyword(s):  
Rhesus Monkey ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Peripheral Blood ◽  
Human Fibroblast ◽  
Rhesus Monkeys ◽  
Human Fibroblasts ◽  
Electron Microscopic ◽  
Specific Antisera ◽  
Peripheral Blood Leucocytes

Herpes-like viruses were isolated from rhesus monkey peripheral blood leucocytes when co-cultivated with WI-38 cells. The virus was originally designated rhesus leucocyte-associated herpesvirus (LAHV) and subsequently called Herpesvirus mulatta (HVM). The original isolations were from juvenile rhesus monkeys shown to be free of antibody to rhesus cytomegalic virus. The virus could only be propagated in human or simian fibroblasts. Use of specific antisera developed from HVM showed no relationship between this virus and other herpesviruses. An electron microscopic study was undertaken to determine the morphology of Herpesvirus mulatta (HVM) in infected human fibroblasts.

Fine structure and properties of defects in naturally occurring silicates and oxides

1990 ◽  
Vol 48 (4) ◽  
pp. 460-461
Author(s):  
David R. Veblen
Keyword(s):  
Chemical Reactions ◽  
High Resolution Electron Microscopy ◽  
Extended Defects ◽  
Single Chain ◽  
Naturally Occurring ◽  
Resolution Electron ◽  
Fine Structures ◽  
Image Simulations ◽  
Similar Crystal Structure

Extended defects and interfaces control many processes in rock-forming minerals, from chemical reactions to rock deformation. In many cases, it is not the average structure of a defect or interface that is most important, but rather the structure of defect terminations or offsets in an interface. One of the major thrusts of high-resolution electron microscopy in the earth sciences has been to identify the role of defect fine structures in reactions and to determine the structures of such features. This paper will review studies using HREM and image simulations to determine the structures of defects in silicate and oxide minerals and present several examples of the role of defects in mineral chemical reactions. In some cases, the geological occurrence can be used to constrain the diffusional properties of defects.The simplest reactions in minerals involve exsolution (precipitation) of one mineral from another with a similar crystal structure, and pyroxenes (single-chain silicates) provide a good example. Although conventional TEM studies have led to a basic understanding of this sort of phase separation in pyroxenes via spinodal decomposition or nucleation and growth, HREM has provided a much more detailed appreciation of the processes involved.

Role of Flavonoids in Neurodegenerative Disorders with Special Emphasis on Tangeritin

2019 ◽  
Vol 18 (8) ◽  
pp. 581-597 ◽  
Author(s):  
Ambreen Fatima ◽  
Yasir Hasan Siddique
Keyword(s):  
Medicinal Plants ◽  
Mechanism Of Action ◽  
Neurodegenerative Disorders ◽  
Treatment Strategies ◽  
Dietary Supplementation ◽  
Plant Polyphenols ◽  
Promising Candidate ◽  
Naturally Occurring ◽  
The Brain

Flavonoids are naturally occurring plant polyphenols found universally in all fruits, vegetables and medicinal plants. They have emerged as a promising candidate in the formulation of treatment strategies for various neurodegenerative disorders. The use of flavonoid rich plant extracts and food in dietary supplementation have shown favourable outcomes. The present review describes the types, properties and metabolism of flavonoids. Neuroprotective role of various flavonoids and the possible mechanism of action in the brain against the neurodegeneration have been described in detail with special emphasis on the tangeritin.

Monosodium Glutamate Toxicity and the Possible Protective Role of L–Carnitine

2018 ◽  
Vol 6 (1) ◽  
pp. 45-56
Author(s):  
Lalrinzuali Sailo ◽  
◽  
Meesala Krishna Murthy ◽  
Khandayataray Pratima ◽  
Vikas Kumar Roy ◽  
...  
Keyword(s):  
Human Subjects ◽  
Monosodium Glutamate ◽  
Essential Amino Acids ◽  
Protective Role ◽  
Glutamate Toxicity ◽  
Common Salt ◽  
Genotoxic Effects ◽  
Naturally Occurring ◽  
Flavour Enhancer

Monosodium glutamate is naturally available non-essential amino acids, which found in naturally occurring foods and used as flavour enhancer worldwide. Monosodium glutamate is believed to be linked with diverse health problems. The aim of the study was toxic effects of monosodium glutamate (MSG) and the protective role of L-carnitine, light on the available literature from last 25 years about diverse toxicity studies which had been carried out on animal and human models. Google scholar, NCBI, PUBMED, EMBASE, Wangfang databases, and Web of Science databases were used to retrieve the available studies. MSG was linked with deleterious effects particularly in animals including induction of obesity, diabetes, hepatotoxic, neurotoxic and genotoxic effects showed in Literature. Few reports revealed increased hunger, food intake, and obesity in human subjects due to MSG consumption. Hepatotoxic, neurotoxic, and genotoxic effects of monosodium glutamate on humans carried out very limitedly. High consumption of monosodium glutamate may be linked with harmful health effects showed in available literatures. So, it is recommended to use common salt instead of MSG. Furthermore, intensive research is required to explore monosodium glutamate–related molecular and metabolic mechanisms. L-carnitine can protect from Hepatotoxic, neurotoxic, renal impairment and genotoxic effects functionally, biochemically and histopathologically with a corresponding reduction of oxidative stress.

How Artefacts Do Leadership: A Ventriloquial Analysis

2021 ◽  
pp. 089331892199807
Author(s):  
Jonathan Clifton ◽  
Fernando Fachin ◽  
François Cooren
Keyword(s):  
Organizational Communication ◽  
Recent Work ◽  
Distributed Leadership ◽  
Network Theory ◽  
Actor Network Theory ◽  
Fine Grained ◽  
Naturally Occurring ◽  
Human Actors

To date there has been little work that uses fine-grained interactional analyses of the in situ doing of leadership to make visible the role of non-human as well as human actants in this process. Using transcripts of naturally-occurring interaction as data, this study seeks to show how leadership is co-achieved by artefacts as an in-situ accomplishment. To do this we situate this study within recent work on distributed leadership and argue that it is not only distributed across human actors, but also across networks that include both human and non-human actors. Taking a discursive approach to leadership, we draw on Actor Network Theory and adopt a ventriloquial approach to sociomateriality as inspired by the Montreal School of organizational communication. Findings indicate that artefacts “do” leadership when a hybrid presence is made relevant to the interaction and when this presence provides authoritative grounds for influencing others to achieve the group’s goals.

scholarly journals Selenium and Dogs: A Systematic Review

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 418
Author(s):  
Viola Zentrichová ◽  
Alena Pechová ◽  
Simona Kovaříková
Keyword(s):  
Male Fertility ◽  
Clinical Signs ◽  
Complex Data ◽  
Selenium Status ◽  
Dog Food ◽  
Balanced Diet ◽  
Naturally Occurring ◽  
Correct Function ◽  
Indirect Assay

The intent of this review is to summarize the knowledge about selenium and its function in a dog’s body. For this purpose, systematic literature search was conducted. For mammals, including dogs, a balanced diet and sufficient intake of selenium are important for correct function of metabolism. As for selenium poisoning, there are no naturally occurring cases known. Nowadays, we do not encounter clinical signs of its deficiency either, but it can be subclinical. For now, the most reliable method of assessing selenium status of a dog is measuring serum or plasma levels. Levels in full blood can be measured too, but there are no reference values. The use of glutathione peroxidase as an indirect assay is questionable in canines. Commercial dog food manufactures follow recommendations for minimal and maximal selenium levels and so dogs fed commercial diets should have balanced intake of selenium. For dogs fed home-made diets, complex data are missing. However, subclinical deficiency seems to affect, for example, male fertility or recovery from parasitical diseases. Very interesting is the role of selenium in prevention and treatment of cancer.

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