scholarly journals Plasma Concentrations of Lutein and Zeaxanthin, Macular Pigment Optical Density, and Their Associations With Cognitive Performances Among Older Adults

2018 ◽  
Vol 59 (5) ◽  
pp. 1828 ◽  
Author(s):  
Soufiane Ajana ◽  
Daniela Weber ◽  
Catherine Helmer ◽  
Bénédicte M. Merle ◽  
Wolfgang Stuetz ◽  
...  
Keyword(s):  
Older Adults ◽  
Optical Density ◽  
Plasma Concentrations ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

scholarly journals Rod-Mediated Dark Adaptation and Macular Pigment Optical Density in Older Adults with Normal Maculas

2018 ◽  
Vol 43 (7) ◽  
pp. 913-920 ◽  
Author(s):  
Anna V. Zarubina ◽  
Carrie E. Huisingh ◽  
Mark E. Clark ◽  
Kenneth R. Sloan ◽  
Gerald McGwin ◽  
...  
Keyword(s):  
Older Adults ◽  
Optical Density ◽  
Dark Adaptation ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

scholarly journals Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults

2013 ◽  
Vol 34 (11) ◽  
pp. 2449-2456 ◽  
Author(s):  
Joanne Feeney ◽  
Ciarán Finucane ◽  
George M. Savva ◽  
Hilary Cronin ◽  
Stephen Beatty ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Performance ◽  
Optical Density ◽  
Large Population ◽  
Population Based ◽  
Macular Pigment ◽  
Macular Pigment Optical Density

scholarly journals The ALGOVUE Clinical Trial: Effects of the Daily Consumption of Eggs Enriched with Lutein and Docosahexaenoic Acid on Plasma Composition and Macular Pigment Optical Density

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3347
Author(s):  
Coralie Schnebelen-Berthier ◽  
Niyazi Acar ◽  
Emilie Simon ◽  
Clémentine Thabuis ◽  
Anne Bourdillon ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Docosahexaenoic Acid ◽  
Optical Density ◽  
Plasma Concentrations ◽  
Density Lipoprotein ◽  
Macular Pigment ◽  
Standard Group ◽  
Macular Pigment Optical Density ◽  
Daily Consumption ◽  
Essential Components

Background. Carotenoids and docosahexaenoic acid (DHA) were identified as essential components for eye health and are both naturally present in eggs. Objective. We aimed to evaluate the effect of the daily consumption of two eggs enriched with lutein/zeaxanthin and DHA on macular pigment optical density (MPOD) and on circulating xanthophyll and fatty acid concentrations in healthy participants. Methods. Ninety-nine healthy volunteers consumed either two standard eggs or two enriched eggs per day for 4 months. MPOD was measured at baseline (V0) and at follow-up (V4) using a modified confocal scanning laser ophthalmoscope (primary outcome). Blood samples were collected to determine total plasma and lipoprotein fatty acids and lutein/zeaxanthin compositions at V0 and V4 (secondary outcomes). Results. A slight but significant increase in MPOD was observed for all study participants consuming two eggs per day for 4 months at all eccentricities (0.5°, 1°, 2°, and 4°). Plasma and lipoprotein lutein, zeaxanthin, and DHA concentrations significantly increased in both groups but were greater in the enriched group (for the enriched group (V0 vs. V4): lutein, 167 vs. 369 ng/mL; zeaxanthin, 17.7 vs. 29.2 ng/mL; DHA, 1.89 vs. 2.56% of total fatty acids). Interestingly, lutein from high-density lipoprotein (HDL) was strongly correlated with MPOD at 0.5 and 1° eccentricities (rho = 0.385, p = 0.008, and rho = 0.461, p = 0.001, respectively). Conclusions. MPOD was slightly increased in both groups. Lutein, zeaxanthin, and DHA plasma concentrations were strongly enhanced in the enriched group compared with the standard group. A significant correlation was found between MPOD level and lutein concentration in HDL.

The role of the macular pigment optical density measurement in the diagnosis of eye diseases

2016 ◽  
Vol 16 (4) ◽  
pp. 197-200
Author(s):  
E.N. Eskina ◽  
◽  
E.A. Egorov ◽  
A.V. Belogurova ◽  
А.А. Gvetadze ◽  
...  
Keyword(s):  
Optical Density ◽  
Density Measurement ◽  
Macular Pigment ◽  
Eye Diseases ◽  
Macular Pigment Optical Density ◽  
Optical Density Measurement

scholarly journals Macular Pigment Optical Density and Photoreceptor Outer Segment Length as Predisease Biomarkers for Age-Related Macular Degeneration

2020 ◽  
Vol 9 (5) ◽  
pp. 1347 ◽  
Author(s):  
Norihiro Nagai ◽  
Sakiko Minami ◽  
Misa Suzuki ◽  
Hajime Shinoda ◽  
Toshihide Kurihara ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Optical Density ◽  
Outer Segment ◽  
Macular Pigment ◽  
Age Related Macular Degeneration ◽  
Segment Length ◽  
Macular Pigment Optical Density ◽  
Photoreceptor Outer Segment ◽  
Age Related ◽  
Fellow Eyes

To explore predisease biomarkers, which may help screen for the risk of age-related macular degeneration (AMD) at very early stages, macular pigment optical density (MPOD) and photoreceptor outer segment (PROS) length were analyzed. Thirty late AMD fellow eyes, which are at high risk and represent the predisease condition of AMD, were evaluated and compared with 30 age-matched control eyes without retinal diseases; there was no early AMD involvement in the AMD fellow eyes. MPOD was measured using MPS2® (M.E. Technica Co. Ltd., Tokyo, Japan), and PROS length was measured based on optical coherence tomography images. MPOD levels and PROS length in the AMD fellow eyes were significantly lower and shorter, respectively, than in control eyes. MPOD and PROS length were positively correlated in control eyes (R = 0.386; p = 0.035) but not in AMD fellow eyes. Twenty (67%) AMD fellow eyes met the criteria of MPOD < 0.65 and/or PROS length < 35 μm, while only five (17%) control eyes did. After adjusting for age and sex, AMD fellow eyes more frequently satisfied the definition (p < 0.001; 95% confidence interval, 3.50–60.4; odds ratio, 14.6). The combination of MPOD and PROS length may be a useful biomarker for screening predisease AMD patients, although further studies are required in this regard.

scholarly journals Macular pigment optical density in central serous chorioretinopathy

2021 ◽  
Vol 13 ◽  
pp. 251584142199719
Author(s):  
Burcu Polat Gultekin ◽  
Esra Sahli
Keyword(s):  
Confidence Interval ◽  
Optical Density ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Retinal Thickness ◽  
Macular Pigment ◽  
Central Retinal Thickness ◽  
Macular Pigment Optical Density ◽  
Chronic Central Serous Chorioretinopathy ◽  
Acute Central Serous Chorioretinopathy

Purpose: The aim of our study was to evaluate the macular pigment optical density in patients with acute and chronic central serous chorioretinopathy and to describe the association between central retinal thickness and choroidal thickness with the macular pigment optical density. Materials and Methods: Eyes with acute central serous chorioretinopathy and chronic central serous chorioretinopathy (patients, who were diagnosed as having disease activity for 6 months) were included in this study. Macular pigment was measured using the heterochromatic flicker technique of the MPS II device for both eyes in patients with acute and chronic central serous chorioretinopathy and in control subjects. Results: Twenty-seven eyes with acute central serous chorioretinopathy, 23 eyes with chronic central serous chorioretinopathy, and 25 control eyes were enrolled. The mean macular pigment optical density in chronic central serous chorioretinopathy (0.480 ± 0.16 density unit (95% confidence interval: 0.390–0.570) was found to be significantly lower than in the control eyes (0.571 ± 0.128 density unit) (95% confidence interval: 0.480–0.670) ( p = 0.007). In correlation analysis, no significant association was detected between the central retinal thickness, choroidal thickness, and macular pigment optical density values in central serous chorioretinopathy group ( p = 0.31, p = 0.71). Conclusion: Macular pigment optical density levels were significantly lower in chronic central serous chorioretinopathy patients than in controls, possibly due to degeneration of the neurosensorial retina, as a result of the long-term persistence of subretinal fluid. There was not a significant correlation between choroidal thickness and macular pigment optical density levels in central serous chorioretinopathy group.

Macular pigment optical density in aging eye

2013 ◽  
Vol 251 (12) ◽  
pp. 2831-2832
Author(s):  
Lin Miao ◽  
Zhen-Yong Zhang ◽  
Zhi-Qiang Yu ◽  
Chong-Da Chen
Keyword(s):  
Optical Density ◽  
Macular Pigment ◽  
Macular Pigment Optical Density
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