Retinal Vessel Oxygen Saturation under Flicker Light Stimulation in Patients with Nonproliferative Diabetic Retinopathy

2012 ◽  
Vol 53 (7) ◽  
pp. 4063 ◽  
Author(s):  
Martin Hammer ◽  
Tabitha Heller ◽  
Susanne Jentsch ◽  
Jens Dawczynski ◽  
Dietrich Schweitzer ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Oxygen Saturation ◽  
Retinal Vessel ◽  
Light Stimulation ◽  
Nonproliferative Diabetic Retinopathy ◽  
Flicker Light

Dynamic Responses in Retinal Vessel Caliber With Flicker Light Stimulation in Eyes With Diabetic Retinopathy

2014 ◽  
Vol 55 (8) ◽  
pp. 5207 ◽  
Author(s):  
Laurence S. Lim ◽  
Lieng H. Ling ◽  
Peng Guan Ong ◽  
Wallace Foulds ◽  
E. Shyong Tai ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Retinal Vessel ◽  
Dynamic Responses ◽  
Light Stimulation ◽  
Retinal Vessel Caliber ◽  
Flicker Light

scholarly journals Dynamic Responses in Retinal Vessel Caliber With Flicker Light Stimulation and Risk of Diabetic Retinopathy and Its Progression

2017 ◽  
Vol 58 (5) ◽  
pp. 2449 ◽  
Author(s):  
Laurence S. Lim ◽  
Lieng H. Ling ◽  
Peng Guan Ong ◽  
Wallace Foulds ◽  
E. Shyong Tai ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Retinal Vessel ◽  
Dynamic Responses ◽  
Light Stimulation ◽  
Retinal Vessel Caliber ◽  
Flicker Light

Venular oxygen saturation is increased in young patients with type 1 diabetes and mild nonproliferative diabetic retinopathy

2020 ◽  
Vol 98 (8) ◽  
pp. 800-807 ◽  
Author(s):  
Nina C.B.B. Veiby ◽  
Aida Simeunovic ◽  
Martin Heier ◽  
Cathrine Brunborg ◽  
Naila Saddique ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Oxygen Saturation ◽  
Young Patients ◽  
Nonproliferative Diabetic Retinopathy

Retinal Venous Oxygen Saturation Increases by Flicker Light Stimulation

2011 ◽  
Vol 52 (1) ◽  
pp. 274 ◽  
Author(s):  
Martin Hammer ◽  
Walthard Vilser ◽  
Thomas Riemer ◽  
Fanny Liemt ◽  
Susanne Jentsch ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Light Stimulation ◽  
Venous Oxygen Saturation ◽  
Flicker Light

Impaired retinal microvascular function predicts long-term adverse events in patients with cardiovascular disease

2020 ◽  
Author(s):  
James D Theuerle ◽  
Ali H Al-Fiadh ◽  
Fakir M Amirul Islam ◽  
Sheila K Patel ◽  
Louise M Burrell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Endothelial Dysfunction ◽  
Cardiovascular Events ◽  
Retinal Vessel ◽  
Light Stimulation ◽  
Traditional Risk Factors ◽  
Flicker Light ◽  
Retinal Arteriolar

Abstract Aims Endothelial dysfunction is a precursor to the development of symptomatic atherosclerosis. Retinal microvascular reactivity to flicker light stimulation is a marker of endothelial function and can be quantified in vivo. We sought to determine whether retinal microvascular endothelial dysfunction predicts long-term major adverse cardiovascular events (MACE). Methods and results In a single-centre prospective observational study, patients with coronary artery disease (CAD) or cardiovascular risk factors underwent dynamic retinal vessel assessment in response to flicker light stimulation and were followed up for MACE. Retinal microvascular endothelial dysfunction was quantified by measuring maximum flicker light-induced retinal arteriolar dilatation (FI-RAD) and flicker light-induced retinal venular dilatation (FI-RVD). In total, 252 patients underwent dynamic retinal vessel assessment and 242 (96%) had long-term follow-up. Of the 242 patients, 88 (36%) developed MACE over a median period of 8.6 years (interquartile range 6.0–9.1). After adjustment for traditional risk factors, patients within the lowest quintile of FI-RAD had the highest risk of MACE [odds ratio (OR) 5.21; 95% confidence interval (CI) 1.78–15.28]. Patients with lower FI-RAD were also more likely to die (OR 2.09; 95% CI 1.00–4.40, per standard deviation decrease in FI-RAD). In Kaplan–Meier analysis, patients with FI-RAD responses below the cohort median of 1.4% exhibited reduced MACE-free survival (55.5 vs. 71.5%; log-rank P = 0.004). FI-RVD was not predictive of MACE. Conclusion Retinal arteriolar endothelial dysfunction is an independent predictor of MACE in patients with CAD or cardiovascular risk factors. Dynamic retinal vessel analysis may provide added benefit to traditional risk factors in stratifying patients at risk for cardiovascular events.

Albuminuria and retinal vessel density in diabetes without diabetic retinopathy: the Kailuan Eye Study

2020 ◽  
Author(s):  
Qian Wang ◽  
Lili Liu ◽  
Jost B. Jonas ◽  
Bixia Gao ◽  
Shou Ling Wu ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Retinal Vessel ◽  
Vessel Density ◽  
Retinal Vessel Density
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