Comparative Analysis of Repeatability of Manual and Automated Choroidal Thickness Measurements in Nonneovascular Age-Related Macular Degeneration

2013 ◽  
Vol 54 (4) ◽  
pp. 2864 ◽  
Author(s):  
Sieun Lee ◽  
Nader Fallah ◽  
Farzin Forooghian ◽  
Ashley Ko ◽  
Kaivon Pakzad-Vaezi ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Thickness Measurements

scholarly journals Choroidal thickness in normal subjects and in age-related macular degeneration

2014 ◽  
Vol 7 (1) ◽  
pp. 4-7
Author(s):  
Yuriy Sergeyevich Astakhov ◽  
Svetlana Georgiyevna Belekhova ◽  
Nikita Yuryevich Dal
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Groups ◽  
Normal Subjects ◽  
Age Related Macular Degeneration ◽  
Enhanced Depth Imaging ◽  
Foveal Thickness ◽  
Age Related ◽  
Thickness Measurements ◽  
Optical Coherence Tomograph

Results of choroidal thickness measurements in 75 healthy subjects of different age groups (123 eyes) are presented as well as those of 35 patients (45 eyes) with age-related macular degeneration. Examinations were performed with a Spectralis optical coherence tomograph using the regimen of Enhanced Depth Imaging (EDI-OCT). A negative dependence between choroidal thickness and age was found (r = -0.78, p < 0.0001). Sub-foveal thickness of the choroid decreases on average by 2.99 µm for every life year. No significant differences in choroidal thickness of age-related macular degeneration patients and that of healthy people of the same age group were found.

scholarly journals Clustering of eyes with age-related macular degeneration or pachychoroid spectrum diseases based on choroidal thickness profile

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Young Ho Kim ◽  
Boram Lee ◽  
Edward Kang ◽  
Jaeryung Oh
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Soft Drusen ◽  
Pachychoroid Neovasculopathy ◽  
The Common ◽  
Common Pathogenesis ◽  
Clustering Pattern ◽  
Normal Controls

AbstractChoroidal changes have been suggested to be involved in the pathophysiology of both age-related macular degeneration (AMD) and pachychoroid spectrum diseases (PSD). To find out the choroidal characteristics of each disease groups, various groups of AMD and PSD were classified into several clusters according to choroidal profiles based on subfoveal choroidal thickness (CT), peripapillary CT, the ratio of subfoveal CT to peripapillary CT and age. We retrospectively analyzed 661 eyes, including 190 normal controls and 471 with AMD or PSDs. In the AMD groups, eyes with soft drusen or reticular pseudodrusen were belonged to the same cluster as those with classic exudative AMD (all p < 0.001). However, eyes with pachydrusen were not clustered with eyes from other AMD groups; instead, they were classified in the same cluster as eyes from the PSD group (all p < 0.001). In the PSD group, eyes with pachychoroid neovasculopathy were grouped in the same cluster of those with polypoidal choroidal vasculopathy (p < 0.001). The cluster analysis based on the CT profiles, including subfoveal CT, peripapillary CT, and their ratio, revealed a clustering pattern of eyes with AMD and PSDs. These findings support the suggestion that pachydrusen has the common pathogenesis as PSD.

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