Photoreceptor Layer Regeneration is Detectable in the Human Retina Imaged by SD-OCT after Laser Treatment Using Subthreshold Laser Power

2012 ◽  
Vol 53 (11) ◽  
pp. 7019 ◽  
Author(s):  
Gábor György Deák ◽  
Matthias Bolz ◽  
Sonja Prager ◽  
Markus Ritter ◽  
Katharina Kriechbaum ◽  
...  
2014 ◽  
Vol 55 (5) ◽  
pp. 3054 ◽  
Author(s):  
Uri Soiberman ◽  
Michaella Goldstein ◽  
Pazit Pianka ◽  
Anat Loewenstein ◽  
Dafna Goldenberg

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Giuseppe Querques ◽  
Riccardo Sacconi ◽  
Francesco Gelormini ◽  
Enrico Borrelli ◽  
Francesco Prascina ◽  
...  

AbstractThere is a lack of treatment aimed at the regression of reticular pseudodrusen (RPD) secondary to age-related macular degeneration (AMD). The aim of this prospective, pilot study is to evaluate the safety and short-term efficacy of subthreshold laser treatment (SLT) in patients affected by RPD secondary to dry AMD (dAMD). Twenty eyes of 20 patients (mean age 78.4 ± 6.8 years) with RPD secondary to dAMD were prospectively enrolled. All patients were treated in an extrafoveal area of 1.27 mm2 using end-point management yellow subthreshold laser and followed for 3 months. Best-corrected visual acuity was 0.140 ± 0.09 LogMAR at the baseline and no changes were observed during the follow-up (p = 0.232). No significant worsening was disclosed before and after the treatment analyzing the macular sensitivity of the treated area (p = 0.152). No topical and/or systemic side effects were disclosed during the 3-month follow-up. The distribution among the RPD stages changed after the treatment (p < 0.001). In detail, in the treated area, we observed a significant increase in the number of Stage 1 RPD during the follow-up (p = 0.002), associated with a significant decrease of Stage 3 RPD (p = 0.020). Outer nuclear layer (ONL) thickness analysis showed a significant increase after the treatment associated with RPD regression (p = 0.001). End-point management SLT appears a safe treatment for RPD secondary to dAMD, showing short-term safety outcomes. Our results suggest that SLT could be effective in inducing a RPD regression in terms of RPD stage and ONL thickening.


2017 ◽  
Vol 42 (3) ◽  
pp. 204-209 ◽  
Author(s):  
Joost Akkermans ◽  
Loes van der Donk ◽  
Suzanne H.P. Peeters ◽  
Sjoerd van Tuijl ◽  
Johanna M. Middeldorp ◽  
...  
Keyword(s):  

2011 ◽  
Vol 183 ◽  
pp. 215-224 ◽  
Author(s):  
A. Zieliński ◽  
M. Jażdżewska ◽  
J. Łubiński ◽  
Waldemar Serbiński

The titanium and its alloys can be subjected to surface treatment, including laser treatment. In this work a new laser treatment at cryogenic conditions of Ti6Al4V alloy has been described. The work has been aimed at establishing whether such surface treatment could be suitable for implants working under wear in biological corrosive environment. The remelting has been made with the use of CO2 continuous work laser at laser power between 3 and 6 kW, at scan rate 0.5 and 1 m/s. The microstructure, surface topography, hardness, microhardness and wear linear rate and mass loss under tribological tests made in Ringer`s solution have been made. The results have shown that despite the surface cracking the tribological properties in simulated body fluid have been substantially improved.


2021 ◽  
Author(s):  
Yongpeng Zhang ◽  
Jipeng Li ◽  
Xusheng Cao ◽  
Haiying Zhou ◽  
Liyun Jia ◽  
...  

Abstract Background We investigate the SD-OCT features of sub-inner limiting membrane (sub-ILM) hemorrhage after 577nm laser membranotomy. Methods The ocular fundus photography and SD-OCT of patients who received 577nm laser membranotomy for sub-ILM hemorrhage were assessed from January 2017 to March 2021 in this retrospective cases series study. Results Total of 7 patients (7 eyes) were enrolled in this study, in which 3 were female and 4 were male. The SD-OCT of ILM after laser treatment showed two distinctive features: the ILM falling back to retina (4 cases) or persistent unsealed ILM which forming premacular cavity (3 cases). The SD-OCT of macular fovea after laser treatment showed three features: normal contour (3 cases), macular hole (1 cases) and epiretinal membrane (1 case). The outer retina showed “peg-like” or “patchy-like” structure on the site of ILM attached to retina.Conclusions 577nm laser is effective in treating of sub-ILM hemorrhage and SD-OCT is effective for diagnosis and following-up of sub-ILM hemorrhage.


2012 ◽  
Vol 43 (6) ◽  
pp. S16-S24 ◽  
Author(s):  
Ik Soo Byon ◽  
Hyun Jun Park ◽  
Sung Who Park ◽  
Kyung Ho Kim ◽  
Ji Eun Lee ◽  
...  

Retina ◽  
2011 ◽  
Vol 31 (2) ◽  
pp. 235-242 ◽  
Author(s):  
Francesca Mojana ◽  
Manpreet Brar ◽  
Lingyun Cheng ◽  
Dirk-Uwe G Bartsch ◽  
William R Freeman

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Sharon Y. L. Chua ◽  
◽  
Baljean Dhillon ◽  
Tariq Aslam ◽  
Konstantinos Balaskas ◽  
...  

AbstractSpectral-domain OCT (SD-OCT) provides high resolution images enabling identification of individual retinal layers. We included 32,923 participants aged 40–69 years old from UK Biobank. Questionnaires, physical examination, and eye examination including SD-OCT imaging were performed. SD OCT measured photoreceptor layer thickness includes photoreceptor layer thickness: inner nuclear layer-retinal pigment epithelium (INL-RPE) and the specific sublayers of the photoreceptor: inner nuclear layer-external limiting membrane (INL-ELM); external limiting membrane-inner segment outer segment (ELM-ISOS); and inner segment outer segment-retinal pigment epithelium (ISOS-RPE). In multivariate regression models, the total average INL-RPE was observed to be thinner in older aged, females, Black ethnicity, smokers, participants with higher systolic blood pressure, more negative refractive error, lower IOPcc and lower corneal hysteresis. The overall INL-ELM, ELM-ISOS and ISOS-RPE thickness was significantly associated with sex and race. Total average of INL-ELM thickness was additionally associated with age and refractive error, while ELM-ISOS was additionally associated with age, smoking status, SBP and refractive error; and ISOS-RPE was additionally associated with smoking status, IOPcc and corneal hysteresis. Hence, we found novel associations of ethnicity, smoking, systolic blood pressure, refraction, IOPcc and corneal hysteresis with photoreceptor thickness.


Author(s):  
M. Groc ◽  
L. Pawlowski ◽  
I. Smurov

Abstract Paper presents a study of modeling and numerical simulation of laser engraving process. The 1-D simulation concerned CO2 c.w. pulsed laser engraving of plasma sprayed alumina, titania and aluminum titanate coatings. These coatings will possibly replace the Cr2O3 ones used currently in manufacturing of anilox rolls. The model was refined in comparison to the previous one (1) by taking into account the speed of the roll at the engraving. The actual thermophysical coefficients of plasma sprayed alumina, titania and aluminum titanate were input to the computations. The model enabled calculation of the engraving's depth in function of the principal laser treatment parameters viz. pulse length and laser power density. Finally, the overflow effect at the laser treatment of new ceramics was discussed and compared to that occurring at Cr2O3 engraving.


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