scholarly journals The International Workshop on Meibomian Gland Dysfunction: Report of the Subcommittee on Tear Film Lipids and Lipid–Protein Interactions in Health and Disease

2011 ◽  
Vol 52 (4) ◽  
pp. 1979 ◽  
Author(s):  
Kari B. Green-Church ◽  
Igor Butovich ◽  
Mark Willcox ◽  
Douglas Borchman ◽  
Friedrich Paulsen ◽  
...  
Keyword(s):  
Protein Interactions ◽  
International Workshop ◽  
Tear Film ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
Health And Disease ◽  
Lipid Protein Interactions

scholarly journals Effects of a New Eyelid Shampoo on Lid Hygiene and Eyelash Length in Patients with Meibomian Gland Dysfunction: A Comparative Open Study

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Asuka Kobayashi ◽  
Takeshi Ide ◽  
Teruki Fukumoto ◽  
Emiko Miki ◽  
Kazuo Tsubota ◽  
...  
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
Controlled Study ◽  
Subjective Symptoms ◽  
Eyelid Margin ◽  
Before And After ◽  
And Function ◽  
Lid Hygiene

Purpose. Meibomian gland dysfunction (MGD) can lead to abnormalities in the composition and function of tear film, resulting in dry eye. Eyelid hygiene is a key to management of MGD. We tested a novel eyelid shampoo (Eye Shampoo Long, ESL) for its ability to maintain lid hygiene. This shampoo is nonirritating and can potentially lengthen eyelashes. This study was aimed to evaluate the efficacy of ESL in the treatment of MGD and its effects on eyelash length. Methods. Ten patients with MGD and 10 healthy subjects without MGD applied ESL twice daily for 8 weeks. Patients were examined for lid margin and dry eye before and after the trial. Subjective symptoms were evaluated. Eyelash length was measured at baseline and at the end of the trial. Results. In the MGD group, significant improvements were observed in subjective symptoms obstruction of the meibomian orifice, secretion of meibum, eyelashes contamination, eyelid margin foam, and SPK. Eyelash length became significantly longer. Conclusions. Maintaining eyelid hygiene using ESL improved the eyelid margins and symptoms of dry eye in MGD patients and increased eyelash length. These findings are promising and warrant confirmation in a larger randomized controlled study.

scholarly journals The International Workshop on Meibomian Gland Dysfunction: Executive Summary

2011 ◽  
Vol 52 (4) ◽  
pp. 1922 ◽  
Author(s):  
Kelly K. Nichols ◽  
Gary N. Foulks ◽  
Anthony J. Bron ◽  
Ben J. Glasgow ◽  
Murat Dogru ◽  
...  
Keyword(s):  
International Workshop ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
Executive Summary

scholarly journals Effects of Eyelid Warming Devices on Tear Film Parameters in Normal Subjects and Patients with Meibomian Gland Dysfunction

2015 ◽  
Vol 13 (4) ◽  
pp. 321-330 ◽  
Author(s):  
Reiko Arita ◽  
Naoyuki Morishige ◽  
Rika Shirakawa ◽  
Yoichi Sato ◽  
Shiro Amano
Keyword(s):  
Tear Film ◽  
Normal Subjects ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
Warming Devices

scholarly journals Androgen and meibomian gland dysfunction: from basic molecular biology to clinical applications

2021 ◽  
Vol 14 (6) ◽  
pp. 915-922
Author(s):  
Li-Xiang Wang ◽  
Keyword(s):  
Tear Film ◽  
Meibomian Gland ◽  
The Body ◽  
Meibomian Gland Dysfunction ◽  
Evidence Based ◽  
Lipid Layer ◽  
Normal Functions ◽  
Potential Applications ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Meibomian gland, the largest sebaceous gland of the body, is responsible for the biosynthesis of lipid layer of the tear film to prevent excessive evaporation. The loss of normal functions of meibomian gland, known as meibomian gland dysfunction (MGD), is a chronic disease and is the leading cause of dry eye symptoms in the clinics. Studies have found sex hormones, especially androgen, play vital roles in the regulation of the functions of meibomian gland. Recently, androgen has also been preliminarily applied in clinics for the treatment of MGD and showed promising results, especially in people with endogenous androgen deficiency. This review summarized the mechanisms of the function of androgen on meibomian gland based on molecular, animal, and clinical studies, and proposed evidence-based views about its potential applications for the treatment of MGD.

scholarly journals A Case of Sebaceous Adenitis and Concurrent Meibomian Gland Dysfunction in a Dog

2020 ◽  
Vol 7 (2) ◽  
pp. 37 ◽  
Author(s):  
Roberta Sartori ◽  
Claudio Peruccio
Keyword(s):  
Clinical Signs ◽  
Tear Film ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
Sebaceous Glands ◽  
Anatomy And Physiology ◽  
Exfoliative Dermatitis ◽  
Dermatological Condition ◽  
Mongrel Dog ◽  
Sebaceous Adenitis

Sebaceous adenitis and concurrent meibomian gland dysfunction (MGD) were diagnosed in a two-year-old mongrel dog presenting with hypotrichosis, exfoliative dermatitis and blepharitis. Diagnosis of sebaceous adenitis was based on history, clinical signs, the histological demonstration of multifocal lymphohistiocytic and neutrophilic inflammation targeting the sebaceous glands and sebaceous glands loss. MGD was diagnosed by non-contact infrared meibography followed by tear film lipid layer interferometric evaluation. Ciclosporin and sebolytic shampoos controlled the dermatological condition, while doxycycline, warm compresses, palpebral massages and tobramycin/dexamethasone ointment controlled the blepharitis. This case report should stimulate clinicians to investigate MGD in dogs suffering from sebaceous adenitis, because the meibomian and sebaceous glands share similar anatomy and physiology.

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