scholarly journals Structural Correlation Between the Nerve Fiber Layer and Retinal Ganglion Cell Loss in Mice with Targeted Disruption of theBrn3bGene

2011 ◽  
Vol 52 (8) ◽  
pp. 5226 ◽  
Author(s):  
Andrew S. Camp ◽  
Marco Ruggeri ◽  
Gustavo C. Munguba ◽  
Mary L. Tapia ◽  
Simon W.M. John ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
Cell Loss ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Targeted Disruption ◽  
Nerve Fiber Layer ◽  
Structural Correlation

scholarly journals Nerve Fiber Layer Thinning Lags Retinal Ganglion Cell Density Following Crush Axonopathy

2014 ◽  
Vol 55 (10) ◽  
pp. 6505 ◽  
Author(s):  
Gustavo C. Munguba ◽  
Sanja Galeb ◽  
Yuan Liu ◽  
David C. Landy ◽  
Daisy Lam ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Cell Density ◽  
Retinal Ganglion Cell ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Nerve Fiber Layer

scholarly journals Estimated Retinal Ganglion Cell Counts in Glaucomatous Eyes with Localized Retinal Nerve Fiber Layer Defects

2013 ◽  
Vol 156 (3) ◽  
pp. 578-587.e1 ◽  
Author(s):  
Andrew J. Tatham ◽  
Robert N. Weinreb ◽  
Linda M. Zangwill ◽  
Jeffrey M. Liebmann ◽  
Christopher A. Girkin ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
Retinal Nerve Fiber Layer ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Cell Counts ◽  
Retinal Nerve Fiber

scholarly journals Retinal Ganglion Cell Layer Thinning Followed By Retinal Nerve Fiber Layer Thinning In Patients with Uveitis

2016 ◽  
Vol 1 (2) ◽  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Retinal Ganglion Cell Layer

In the model of experimentally induced ischemia- reperfusion injury, retinal ganglion cells (RGC) expressing the gene AP-1 result apoptosis. The inflammation mediators, such as TNF-α, IL-1β, etc. lead RGC to apoptosis, that may lead the thinning of the retinal ganglion cell layer (RGCL) followed by the optic nerve fiber layer (RNFL) thinning. In his study we observed retinal ganglion cell and optic nerve fiber layer thinning in patients with various uveitis, that the pathological features appear obliterative vasculitis, using the optical coherence tomography (OCT) imaging analyses. Subjects were 182 eyes of 91 uveitis patients without glaucoma. Comparison were patients with normal tension glaucoma (NTG). Image analyses were conducted with 3D OCT-2000. As a result average RGCL thickness values in the patients with uveitis were significantly(p<0.01) thinner than those in healthies. Cycle scan findings of RNFL around the optic disc in the patients with uveitis showed significant thinning especially at nasal side. The retinal ganglion cell layer thinning followed by the retinal nerve fiber thinning in the patients with various uveitis was observed, and the thinning was similar to that in patients with glaucoma. The observation of RGCL and RNFL thickness may be useful for the diagnosis and the follow-up of uveitis.

scholarly journals Tissue engineering the retinal ganglion cell nerve fiber layer

Biomaterials ◽  
2013 ◽  
Vol 34 (17) ◽  
pp. 4242-4250 ◽  
Author(s):  
Karl E. Kador ◽  
Ramon B. Montero ◽  
Praseeda Venugopalan ◽  
Jonathan Hertz ◽  
Allison N. Zindell ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Nerve Fiber Layer

scholarly journals Comparison of Retinal Nerve Fiber Layer Thinning and Retinal Ganglion Cell Loss After Optic Nerve Transection in Adult Albino Rats

2015 ◽  
Vol 56 (8) ◽  
pp. 4487 ◽  
Author(s):  
Giuseppe Rovere ◽  
Francisco M. Nadal-Nicolás ◽  
Marta Agudo-Barriuso ◽  
Paloma Sobrado-Calvo ◽  
Leticia Nieto-López ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
Retinal Nerve Fiber Layer ◽  
Cell Loss ◽  
Albino Rats ◽  
Retinal Ganglion ◽  
Nerve Transection ◽  
Fiber Layer

In Vivo Imaging of Retinal Ganglion Cell Axons within the Nerve Fiber Layer

2010 ◽  
Vol 51 (4) ◽  
pp. 2011 ◽  
Author(s):  
Akiyasu Kanamori ◽  
Maria-Magdalena Catrinescu ◽  
Manuela Traistaru ◽  
Rachel Beaubien ◽  
Leonard A. Levin
Keyword(s):  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Ganglion Cell ◽  
In Vivo Imaging ◽  
Retinal Ganglion ◽  
Fiber Layer ◽  
Nerve Fiber Layer

SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVIDENCE OF RETINAL NERVE FIBER LAYER AND GANGLION CELL LOSS IN ADULT PATIENTS WITH NEUROFIBROMATOSIS TYPE 1

Retina ◽  
2016 ◽  
Vol 36 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Solmaz Abdolrahimzadeh ◽  
Lorenzo Felli ◽  
Andrea Maria Plateroti ◽  
Andrea Perdicchi ◽  
Maria Teresa Contestabile ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Neurofibromatosis Type 1 ◽  
Cell Loss ◽  
Neurofibromatosis Type ◽  
Fiber Layer ◽  
Nerve Fiber Layer
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