Proteomic Identification of Oxidatively Modified Retinal Proteins in a Chronic Pressure-Induced Rat Model of Glaucoma

2005 ◽  
Vol 46 (9) ◽  
pp. 3177 ◽  
Author(s):  
Gu¨lgu¨n Tezel ◽  
Xiangjun Yang ◽  
Jian Cai
Keyword(s):  
Rat Model ◽  
Proteomic Identification ◽  
Retinal Proteins ◽  
Oxidatively Modified

scholarly journals Proteomic identification of vanin-1 as a marker of kidney damage in a rat model of type 1 diabetic nephropathy

2011 ◽  
Vol 80 (3) ◽  
pp. 272-281 ◽  
Author(s):  
Tim Fugmann ◽  
Beatrice Borgia ◽  
Csaba Révész ◽  
Mária Godó ◽  
Carol Forsblom ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Rat Model ◽  
Kidney Damage ◽  
Proteomic Identification

scholarly journals Lipid-derived and other oxidative modifications of retinal proteins in a rat model of Smith-Lemli-Opitz syndrome

2019 ◽  
Vol 178 ◽  
pp. 247-254 ◽  
Author(s):  
Rebecca J. Kapphahn ◽  
Michael J. Richards ◽  
Deborah A. Ferrington ◽  
Steven J. Fliesler
Keyword(s):  
Rat Model ◽  
Oxidative Modifications ◽  
Opitz Syndrome ◽  
Retinal Proteins

Proteomic identification of biomarkers in the cerebrospinal fluid in a rat model of nigrostriatal dopaminergic degeneration

2007 ◽  
Vol 85 (16) ◽  
pp. 3607-3618 ◽  
Author(s):  
I. Rite ◽  
S. Argüelles ◽  
J.L. Venero ◽  
S. García-Rodriguez ◽  
A. Ayala ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Rat Model ◽  
Proteomic Identification ◽  
Dopaminergic Degeneration

scholarly journals Extract from Aronia melanocarpa L. Berries Protects Against Cadmium-induced Lipid Peroxidation and Oxidative Damage to Proteins and DNA in the Liver: A Study using a Rat Model of Environmental Human Exposure to this Xenobiotic

Nutrients ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 758 ◽  
Author(s):  
Magdalena Mężyńska ◽  
Małgorzata Brzóska ◽  
Joanna Rogalska ◽  
Anna Galicka
Keyword(s):  
Lipid Peroxidation ◽  
Rat Model ◽  
Protective Action ◽  
Lipid Peroxides ◽  
Oxidative Injury ◽  
Protein Carbonyl ◽  
Female Rat ◽  
Aronia Melanocarpa ◽  
Oxidatively Modified ◽  
Almost All

It was investigated, using a female rat model of low and moderate exposure of human to cadmium (Cd, 1 and 5 mg Cd/kg diet for 3–24 months), whether a polyphenol-rich 0.1% aqueous extract from Aronia melanocarpa L. berries (AE) may prevent Cd-induced lipid peroxidation and oxidative modifications of proteins and deoxyribonucleic acid (DNA) in the liver. For this purpose, markers of lipid peroxidation (lipid peroxides and 8-isoprostane) and oxidative injury of proteins (protein carbonyl groups and 3-nitrotyrosine) and DNA (8-hydroxy-2′-deoxyguanosine) were measured in this organ. The expression of metallothionein 1 (MT1) and metallothionein 2 (MT2) genes was estimated for a better explanation of the possible mechanisms of protective action of AE against Cd hepatotoxicity. The low and moderate treatment with Cd induced lipid peroxidation and oxidatively modified proteins and DNA, as well as enhanced the expression of MT1 and MT2 in the liver, whereas the co-administration of AE completely prevented almost all of these effects. The results allow us to conclude that the consumption of aronia products under exposure to Cd may offer protection against oxidative injury of the main cellular macromolecules in the liver, including especially lipid peroxidation, and in this way prevent damage to this organ.

scholarly journals Proteomic Identification of Novel Differentiation Plasma Protein Markers in Hypobaric Hypoxia-Induced Rat Model

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e98027 ◽  
Author(s):  
Yasmin Ahmad ◽  
Narendra K. Sharma ◽  
Mohammad Faiz Ahmad ◽  
Manish Sharma ◽  
Iti Garg ◽  
...  
Keyword(s):  
Plasma Protein ◽  
Rat Model ◽  
Hypobaric Hypoxia ◽  
Protein Markers ◽  
Proteomic Identification

Proteomic identification of mitochondrial targets involved in andrographolide sodium bisulfite-induced nephrotoxicity in a rat model

2015 ◽  
Vol 40 (2) ◽  
pp. 592-599 ◽  
Author(s):  
Wen Min Xing ◽  
Tang Juan Yuan ◽  
Jia Dong Xu ◽  
Li Li Gu ◽  
Pei Liang ◽  
...  
Keyword(s):  
Rat Model ◽  
Sodium Bisulfite ◽  
Proteomic Identification
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