scholarly journals Integrated Cognitive Assessment: Speed and Accuracy of Visual Processing as a Proxy to Cognitive Performance

2018 ◽  
Vol 18 (10) ◽  
pp. 104
Author(s):  
Seyed-Mahdi Khaligh-Razavi ◽  
Sina Habibi ◽  
Elham Sadeghi ◽  
Chris Kalafatis
2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Seyed-Mahdi Khaligh-Razavi ◽  
Sina Habibi ◽  
Maryam Sadeghi ◽  
Haniye Marefat ◽  
Mahdiyeh Khanbagi ◽  
...  

2018 ◽  
Author(s):  
Seyed-Mahdi Khaligh-Razavi ◽  
Sina Habibi ◽  
Maryam Sadeghi ◽  
Haniye Marefat ◽  
Mahdiyeh Khanbagi ◽  
...  

AbstractVarious mental disorders are accompanied by some degree of cognitive impairment. Particularly in neurodegenerative disorders, cognitive impairment is the phenotypical hallmark of the disease. Effective, accurate and timely cognitive assessment is key to early diagnosis of this family of mental disorders. Current standard-of-care techniques for cognitive assessment are primarily paper-based, and need to be administered by a healthcare professional; they are additionally language and education-dependent and typically suffer from a learning bias. These tests are thus not ideal for large-scale pro-active cognitive screening and disease progression monitoring. We developed the Integrated Cognitive Assessment (ICA), a 5-minute computerized cognitive assessment tool based on a rapid visual categorization task, in which a series of carefully selected natural images of varied difficulty are presented to participants. Overall 448 participants, across a wide age-range with different levels of education took the ICA test. We compared participants’ ICA test results with a variety of standard pen-and-paper tests that are routinely used to assess cognitive performance. ICA had excellent test-retest reliability, and was significantly correlated with all the reference cognitive tests used here, demonstrating ICA’s ability as one unified test that can assess various cognitive domains.


2016 ◽  
Vol 21 (1) ◽  
pp. 46-51 ◽  
Author(s):  
Yuval Bloch ◽  
Shai Aviram ◽  
Aviv Segev ◽  
Uri Nitzan ◽  
Yechiel Levkovitz ◽  
...  

Objective: We hypothesized that patients with ADHD were typified by distress more than by functional difficulties. Thus, a decline in state anxiety while performing a cognitive task when taking methylphenidate would discriminate between ADHD patients and controls. Method: State anxiety and cognitive performance on a continuous performance test were assessed in ADHD patients and controls with and without taking methylphenidate. Results: State anxiety and cognitive performance improved from baseline in 36 ADHD adults after taking methylphenidate. In 25 controls, cognitive performance improved, but state anxiety did not abate after a recess. In two additional studies, 5 controls were evaluated at baseline and after receiving methylphenidate, and showed improvement in cognitive assessment but not in state anxiety. Five ADHD adults were assessed at baseline and after a recess, and showed no improvement. Conclusion: Our results support the hypothesis that adult ADHD patients are characterized by distress and the relief of this distress under effective therapy as expressed by a decline in state anxiety while they perform a cognitive task.


2020 ◽  
Vol 11 ◽  
Author(s):  
Amanda McCleery ◽  
Jonathan K. Wynn ◽  
Junghee Lee ◽  
Eric A. Reavis ◽  
Joseph Ventura ◽  
...  

2021 ◽  
Vol 23 (Supplement_2) ◽  
pp. ii5-ii5
Author(s):  
Y Wang ◽  
P Ji ◽  
S Guo ◽  
J Liu ◽  
Y Zhai ◽  
...  

Abstract BACKGROUND Cognitive deficit was frequently observed in glioma patients, especially for those on the eloquent area. Considering the increased life expectancy, brain mapping during awake craniotomy was preferentially applied to exacerbate neurocognitive deficits. The aim of the current study was to evaluate the neurocognitive changes during the perioperative period of resection of low-grade glioma (LGG) in the left side eloquent area with awake craniotomy in a major neurosurgical center in China for 5 years. MATERIAL AND METHODS We retrospectively analyzed patients with left-sided glioma in eloquent areas, who received awake craniotomy during 2016–2020. Montreal Cognitive Assessment Scale, BN-20, and EORTC-QLQ-C30 questionnaire were applied for neurological cognitive assessment. We performed a correlation analysis between changes in cognitive performance and tumor characteristics, including tumor location, pathological grade. Treatment-related factors were also analyzed, such as the extent of resection (EOR), preoperative and postoperative Karnofsky Performance Score (KPS), postoperative treatment strategy (chemo- and radiotherapy), progression-free survival (PFS), overall survival (OS). RESULTS 68 patients were included in our current study. For the language domain, memory domain, and executive functions, 7.4% (5/68) patients presented mild postoperative cognitive performance deterioration compared to preoperative. Tumor location was the only factor that greatly influenced the postoperative cognitive performance, while other features (EOR, KPS, pathological grades) and treatment strategy were found no effect on cognitive change. The extent of tumor resection ranged from 81% to 100%. CONCLUSION Our study underlines the importance of the application of brain mapping during awake craniotomy, which helps to maximize extent of tumor resection while preserving cognitive function in individuals with LGG in eloquent regions.


2020 ◽  
Vol 35 (6) ◽  
pp. 808-808
Author(s):  
Stanley A ◽  
Mohebpour I ◽  
Auman B ◽  
Christine B ◽  
Virden T ◽  
...  

Abstract Objective Montreal Cognitive Assessment (MoCA) and Alzheimer’s Disease 8 questionnaire (AD8) are widely used measures for clinical screening of dementia related disorders. Previous research on MoCA and AD8 has been solely focused on participant-report AD8 measures without consideration of informant reports. We hypothesize informant reported AD8 and participant MoCA scores will be inversely related, participant-reported AD8 will be weakly associated with MoCA performance, and informant reported AD8 will more reliably predictor cognitive performance. Methods Participants (N = 212) were seen from 2018 to 2020 through a free community screening service (Brain Health Check-In) at Banner Sun Health Research Institute in Arizona. First and second hypotheses were analyzed with Spearman’s Rho (r), third hypothesis utilized a linear regression. Results Both participant and informant reported AD8 directly correlated with overall cognitive performance classification (r = 0.639 [informant] confidence interval [CI] = .0552–0.712, p < .000; r = 0.610 [participant] CI = 0.518–0.688, p < .000). Informant reported AD8 ratings were significantly inversely correlated with MoCA performance (r = −0.497, p < .000). Participant reported AD8 ratings also inversely correlated with overall MoCA scores with a weaker association (r = −0.296, p < .000). Neither participant nor informant reported AD8 were able to reliably predict categorical cognitive performance classification, but informant reported AD8 (r = −.686, p < .000) did emerge as a reliable predictor of MoCA performance. Conclusion(s) This study extends and reaffirms prior research about AD8 and suggests both informant- and participant-reports are valuable; however, informant often provides more clinically useful information related to cognitive functioning.


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