scholarly journals Local short-term variability of retinal thickness measurements with SD-OCT

2017 ◽  
Vol 17 (7) ◽  
pp. 51
Author(s):  
R. Tzekov ◽  
B. Madow ◽  
M. Chikovsky ◽  
D. Richards
Keyword(s):  
Retinal Thickness ◽  
Short Term ◽  
Thickness Measurements ◽  
Short Term Variability ◽  
Sd Oct

scholarly journals Assessing Errors Inherent in OCT-Derived Macular Thickness Maps

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Daniel Odell ◽  
Adam M. Dubis ◽  
Jackson F. Lever ◽  
Kimberly E. Stepien ◽  
Joseph Carroll
Keyword(s):  
Axial Length ◽  
Retinal Thickness ◽  
Normal Subjects ◽  
Macular Thickness ◽  
Ideal Observer ◽  
Factors Affecting ◽  
Data Collection And Analysis ◽  
Thickness Measurements ◽  
Retinal Pathologies ◽  
Sd Oct

SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness maps. Forty-three patients with various retinal pathologies and 113 normal subjects were imaged using Cirrus HD-OCT. Reduced B-scan density was associated with increased interpolation error in ETDRS macular thickness plots. Correcting for individual differences in axial length revealed modest errors in retinal thickness maps, while more pronounced errors were observed when the ETDRS plot was not positioned at the center of the fovea (which can occur as a result of errant fixation). Cumulative error can exceed hundreds of microns, even under “ideal observer” conditions. This preventable error is particularly relevant when attempting to compare macular thickness maps to normative databases or measuring the area or volume of retinal features.

scholarly journals Retinal thickness among normal myopic Filipinos using spectral domain optical coherence tomography

2020 ◽  
Vol 17 (2) ◽  
pp. 156-169
Author(s):  
Camille Elaine Zabala ◽  
Jubaida Mangondato-Aquino ◽  
Jose Ma. Martinez ◽  
John Mark De Leon
Keyword(s):  
Optical Coherence Tomography ◽  
High Myopia ◽  
Retinal Thickness ◽  
Spectral Domain ◽  
Pathologic Myopia ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Thickness Measurements ◽  
Sd Oct

Purpose: To determine mean macular and retinal nerve fiber layer (RNFL) thickness of myopic Filipinos using spectral domain optical coherence tomography (SD-OCT) and to evaluate influence of age, gender, and degree of myopia. Design: Observational clinic-based cohort. Methods: Participants were divided into two groups: low-moderate myopia [spherical equivalent (SE) -0.50 D to -6.00 D] and high-pathologic myopia (SE < -6.00 D and AL > 26.5 mm). Subgroup analyses between low myopia (refraction < -3.00 D or less) and moderate myopia (> -3.00 D to -6.00 D), and high myopia (> -6.00 D to -8.00 D) and pathologic myopia (more than -8.00 D) were done. Macular and RNFL thickness were measured by a SD-OCT and axial length (AL) with non-contact biometry. Results: Of 156 eyes, 88/156 (56%) had low-moderate myopia, 68/156 (44%) had high-pathologic myopia. There were 67/156 (43%) male and 89/156 (57%) female subjects. Mean central foveal subfield thickness measurements were 264 ± 24 μm for low myopia, 258 ± 17 μm for moderate myopia, 253 ± 25 μm for high myopia, and 218 ± 48 μm for pathologic myopia. Mean RNFL thickness measurements were 105.62 ± 3.89 μmfor low myopia, 97.6 ± 2.45 μm for moderate myopia, 85.9 ± 3.87 μm for high myopia, and 75.14 ± 3.89 μm for pathologic myopia. Average SE (p < 0.0001) decreased while AL (p < 0.0001) increased with more myopia. Myopia and age significantly affected macular and RNFL thickness parameters except for the following where only the degree of myopia was a significant factor: central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses. Conclusion: Retinal SD-OCT thickness measurements decreased with increasing level of myopia and age. Central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses may be more appropriate SD-OCT parameters among myopic Filipino patients to monitor for glaucoma since they may be less influenced by age.

scholarly journals Morphological Changes in Lamellar Macular Holes According to SD-OCT Examination over a Long Observation Period

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1145
Author(s):  
Magdalena Kal ◽  
Izabela Chojnowska-Ćwiąkała ◽  
Mateusz Winiarczyk ◽  
Monika Jasielska ◽  
Jerzy Mackiewicz
Keyword(s):  
Retinal Thickness ◽  
Morphological Changes ◽  
Outer Diameter ◽  
Corrected Visual Acuity ◽  
Macular Holes ◽  
Kolmogorov Smirnov ◽  
Inner Diameter ◽  
Observation Period ◽  
Sd Oct

Background: The aim of this study was to evaluate the quantitative morphological changes in lamellar macular holes (LMHs) based on SD-OCT examinations and to assess the correlations among minimal retinal thickness (MRT), reading vision (RV), and best corrected visual acuity (BCVA) over a 36-month follow-up period. Methods: A group of 40 patients (44 eyes) with LMH was evaluated, with an average age of 69.87 (SD = 10.14). The quantitative parameters monitored in the follow-up period (at 0, 3, 6, 12, 18, 24, 30, and 36 months) were tested for normality of distribution by Shapiro–Wilk and Kolmogorov–Smirnov tests. Results: The RV and BCVA values were stable, and no significant changes were found at any of the check-ups during the 36-month follow-up period (BCVA p = 0.435 and RV p = 0.0999). The analysis of individual quantitative LMH parameters during the 36-month follow-up period did not demonstrate statistically significant differences: MRT (p = 0.461), Max RT temporal (p = 0.051), Max RT nasal (p = 0.364), inner diameter (ID) (p = 0.089), and outer diameter (OD) (p = 0.985). Conclusions: The observations at 0, 6, 12, 18, 24, 30, and 36 months revealed moderate and significant correlations between RV and MRT. No significant correlation between BCVA and MRT was observed.

Interrupter technique in infancy: Higher airway resistance and lower short-term variability in preterm versus term infants

2017 ◽  
Vol 52 (10) ◽  
pp. 1355-1362 ◽  
Author(s):  
Jakob Usemann ◽  
Désirée Demann ◽  
Pinelopi Anagnostopoulou ◽  
Insa Korten ◽  
Olga Gorlanova ◽  
...  
Keyword(s):  
Airway Resistance ◽  
Short Term ◽  
Term Infants ◽  
Short Term Variability

scholarly journals Assessment of Global and Local Alterations in Retinal Layer Thickness in Ins2 (Akita) Diabetic Mice by Spectral Domain Optical Coherence Tomography

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Andrew W. Francis ◽  
Justin Wanek ◽  
Mahnaz Shahidi
Keyword(s):  
Optical Coherence Tomography ◽  
Mouse Model ◽  
Layer Thickness ◽  
Retinal Thickness ◽  
Normative Values ◽  
Retinal Layer ◽  
Wild Type ◽  
Global And Local ◽  
Akita Mice ◽  
Sd Oct

Purpose/Aim. The Ins2 (Akita) mouse is a spontaneous diabetic mouse model with a heterozygous mutation in the insulin 2 gene that results in sustained hyperglycemia. The purpose of the study was to assess global and local retinal layer thickness alterations in Akita mice by analysis of spectral domain optical coherence tomography (SD-OCT) images.Materials and Methods. SD-OCT imaging was performed in Akita and wild-type mice at 12 and 24 weeks of age. Inner retinal thickness (IRT), outer retinal thickness (ORT), total retinal thickness (TRT), and photoreceptor outer segment length (OSL) were measured. Mean global thickness values were compared between Akita and wild-type mice. Local thickness variations in Akita mice were assessed based on normative values in wild-type mice.Results. Akita mice had higher blood glucose levels and lower body weights (p<0.001). On average, IRT, ORT, and TRT were approximately 2% lower in Akita mice than in wild-type mice (p≤0.02). In Akita mice, the percent difference between retinal areas with thickness below and above normative values for IRT, ORT, and TRT was 22%, 32%, and 38%, respectively.Conclusions. These findings support the use of the Akita mouse model to study the retinal neurodegenerative effects of hyperglycemia.

Modeling short-term variability ofα-hexachlorocyclohexane in Northern Hemispheric air

2008 ◽  
Vol 113 (D2) ◽  
Author(s):  
Kaj M. Hansen ◽  
Jesper H. Christensen ◽  
Jørgen Brandt ◽  
Lise M. Frohn ◽  
Camilla Geels ◽  
...  
Keyword(s):  
Short Term ◽  
Northern Hemispheric ◽  
Short Term Variability

scholarly journals Characterizing the Impact of Off-Axis Scan Acquisition on the Reproducibility of Total Retinal Thickness Measurements in SDOCT Volumes

2015 ◽  
Vol 4 (4) ◽  
pp. 3 ◽  
Author(s):  
Bhavna J. Antony ◽  
Paul F. Stetson ◽  
Michael D. Abramoff ◽  
Kyungmoo Lee ◽  
Johanna M. Colijn ◽  
...  
Keyword(s):  
Retinal Thickness ◽  
The Impact ◽  
Thickness Measurements

scholarly journals Short‐term variability in euphotic zone biogeochemistry and primary productivity at Station ALOHA: A case study of summer 2012

2015 ◽  
Vol 29 (8) ◽  
pp. 1145-1164 ◽  
Author(s):  
Samuel T. Wilson ◽  
Benedetto Barone ◽  
Francois Ascani ◽  
Robert R. Bidigare ◽  
Matthew J. Church ◽  
...  
Keyword(s):  
Primary Productivity ◽  
Euphotic Zone ◽  
Short Term ◽  
Station Aloha ◽  
Short Term Variability
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