scholarly journals Characterizing the Impact of Off-Axis Scan Acquisition on the Reproducibility of Total Retinal Thickness Measurements in SDOCT Volumes

2015 ◽  
Vol 4 (4) ◽  
pp. 3 ◽  
Author(s):  
Bhavna J. Antony ◽  
Paul F. Stetson ◽  
Michael D. Abramoff ◽  
Kyungmoo Lee ◽  
Johanna M. Colijn ◽  
...  
Keyword(s):  
Retinal Thickness ◽  
The Impact ◽  
Thickness Measurements

Quality and Reproducibility of Retinal Thickness Measurements in Two Spectral-Domain Optical Coherence Tomography Machines

2011 ◽  
Vol 52 (9) ◽  
pp. 6925 ◽  
Author(s):  
Ilse Krebs ◽  
Eva Smretschnig ◽  
Sarah Moussa ◽  
Werner Brannath ◽  
Irene Womastek ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Thickness Measurements

scholarly journals Impact of Baseline Central Retinal Thickness on Outcomes in the VIVID-DME and VISTA-DME Studies

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Edoardo Midena ◽  
Mark Gillies ◽  
Todd A. Katz ◽  
Carola Metzig ◽  
Chengxing Lu ◽  
...  
Keyword(s):  
Treatment Effect ◽  
Retinal Thickness ◽  
Continuous Variable ◽  
Central Retinal Thickness ◽  
Link Type ◽  
Intravitreal Aflibercept ◽  
Laser Control ◽  
Post Hoc ◽  
The Impact ◽  
Anatomical Outcomes

Purpose. To report the impact of baseline central retinal thickness (CRT) on outcomes in patients with diabetic macular edema (DME) in VIVID-DME and VISTA-DME. Methods. Post hoc analyses of two randomized controlled trials in which 862 DME patients were randomized 1 : 1 : 1 to treatment with intravitreal aflibercept 2.0 mg every 4 weeks (2q4), intravitreal aflibercept 2.0 mg every 8 weeks after five initial monthly doses (2q8), or macular laser photocoagulation at baseline and as needed. We compared visual and anatomical outcomes in subgroups of patients with baseline CRT < 400 μm and ≥400 μm. Results. At weeks 52 and 100, outcomes with intravitreal aflibercept 2q4 and 2q8 were superior to those in laser control-treated patients regardless of baseline CRT. When looked at in a binary fashion, the treatment effect of intravitreal aflibercept versus laser was not significantly better in the ≥400 μm than the <400 μm group; when looked at as a continuous variable, baseline CRT seemed to have an impact on the treatment effect of intravitreal aflibercept versus laser. Conclusions. Post hoc analyses of VIVID-DME and VISTA-DME demonstrated the benefits of intravitreal aflibercept treatment in DME patients with baseline CRT < 400 μm and ≥400 μm. This trial is registered with NCT01331681 and NCT01363440.

scholarly journals Correlation between Macular Pigment Optical Density and Neural Thickness and Volume of the Retina

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 888
Author(s):  
Norihiro Nagai ◽  
Teru Asato ◽  
Sakiko Minami ◽  
Misa Suzuki ◽  
Hajime Shinoda ◽  
...  
Keyword(s):  
Optical Density ◽  
Retinal Thickness ◽  
Outer Nuclear Layer ◽  
Plexiform Layer ◽  
Macular Pigment ◽  
Inner Plexiform Layer ◽  
The Mean ◽  
Short Wavelength Light ◽  
The Impact ◽  
Adult Volunteers

Macular pigment (MP), which is composed of lutein/zeaxanthin/mezo-zeaxanthin, is concentrated in the central part of the retina, the macula. It protects the macula by absorbing short-wavelength light and suppressing oxidative stress. To evaluate whether MP levels are related to retinal neural protection and resulting health, we analyzed the association between the MP optical density (MPOD), and the macular thickness and volumes. Forty-three eyes of 43 healthy adult volunteers (21 men and 22 women; age: 22–48 (average 31.4 ± 1.1) years) were analyzed. Highly myopic eyes (<-6 diopters) were excluded. MPOD was measured using MPS2®, and the neural retinal thickness and volume were measured using optical coherence tomography. The mean MPOD was 0.589 ± 0.024, and it positively correlated with the central retinal thickness (P = 0.017, R = 0.360) and retinal volume of the fovea (1-mm diameter around the fovea; P = 0.029, R = 0.332), parafovea (1–3-mm diameter; P = 0.002, R = 0.458), and macula (6-mm diameter; P = 0.003, R = 0.447). In the macular area (diameter: 6 mm), MPOD was correlated with the retinal neural volume of the ganglion cell layer (P = 0.037, R = 0.320), inner plexiform layer (P = 0.029, R = 0.333), and outer nuclear layer (P = 0.020, R = 0.353). Thus, MPOD may help in estimating neural health. Further studies should determine the impact of MP levels on neuroprotection.

scholarly journals Comparison of Retinal Thickness Measurements Obtained by Four Optical Coherence Tomographers (OCTs)

2017 ◽  
Vol 46 (0) ◽  
pp. 201-207
Author(s):  
Mio Sakate ◽  
Atsushi Fujiwara ◽  
Keisuke Kanenaga ◽  
Yasuhito Goto ◽  
Asuka Inagaki ◽  
...  
Keyword(s):  
Retinal Thickness ◽  
Optical Coherence ◽  
Thickness Measurements

scholarly journals Chorio-retinal thickness measurements in patients with acromegaly

Eye ◽  
2015 ◽  
Vol 29 (8) ◽  
pp. 1111-1112
Author(s):  
K X Cheong ◽  
C S H Tan
Keyword(s):  
Retinal Thickness ◽  
Thickness Measurements

scholarly journals Chorio-retinal thickness measurements in patients with acromegaly

Eye ◽  
2014 ◽  
Vol 28 (11) ◽  
pp. 1350-1354 ◽  
Author(s):  
G Pekel ◽  
F Akin ◽  
M S Ertürk ◽  
S Acer ◽  
R Yagci ◽  
...  
Keyword(s):  
Retinal Thickness ◽  
Thickness Measurements

Quantitative In Vivo Retinal Thickness Measurements in Healthy Subjects

Ophthalmology ◽  
1997 ◽  
Vol 104 (4) ◽  
pp. 639-642 ◽  
Author(s):  
David Landau ◽  
Elad M. Schneidman ◽  
Tzah Jacobovitz ◽  
Yaacov Rozenman
Keyword(s):  
Healthy Subjects ◽  
Retinal Thickness ◽  
Thickness Measurements

Accuracy of retinal thickness measurements obtained with Cirrus optical coherence tomography

2009 ◽  
Vol 93 (11) ◽  
pp. 1461-1467 ◽  
Author(s):  
P A Keane ◽  
P S Mand ◽  
S Liakopoulos ◽  
A C Walsh ◽  
S R Sadda
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Optical Coherence ◽  
Thickness Measurements
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