Cyclodextrins Application in Urease-Based Biosensor for Urea Determination

2018 ◽  
Vol 16 (4) ◽  
pp. 298-303 ◽  
Author(s):  
Svitlana V. Marchenko ◽  
Oleksandr O. Soldatkin ◽  
Lesia A. Kolomiets ◽  
Olexander I. Kornelyuk ◽  
Alexei P. Soldatkin
Keyword(s):  
Urea Determination

Sol–gel-derived thick-film conductometric biosensor for urea determination in serum

2000 ◽  
Vol 404 (2) ◽  
pp. 195-203 ◽  
Author(s):  
Won-Yong Lee ◽  
Seung-Ryeol Kim ◽  
Tae-Han Kim ◽  
Kang Shin Lee ◽  
Min-Chol Shin ◽  
...  
Keyword(s):  
Thick Film ◽  
Sol Gel ◽  
Urea Determination ◽  
Conductometric Biosensor

PEG-based hydrogel-coated test strip for on-site urea determination

2018 ◽  
Vol 68 (10) ◽  
pp. 597-606 ◽  
Author(s):  
Burcin Alev-Tuzuner ◽  
Asli Beyler-Cigil ◽  
Memet Vezir Kahraman ◽  
Aysen Yarat
Keyword(s):  
Test Strip ◽  
Urea Determination

Technology and application of the LTCC-based microfluidic module for urea determination

2015 ◽  
Vol 32 (3) ◽  
pp. 126-132 ◽  
Author(s):  
Karol Malecha ◽  
Elżbieta Remiszewska ◽  
Dorota G Pijanowska
Keyword(s):  
Immobilized Enzyme ◽  
Biological Fluid ◽  
Signal To Noise Ratio ◽  
Type System ◽  
High Signal ◽  
Content Type ◽  
Lab On Chip ◽  
Medical Diagnoses ◽  
Urea Determination ◽  
And Performance

Purpose – The purpose of this paper is to focus on the technology and performance of the miniature microfluidic module for urea determination. The presented module was made using low-temperature co-fired ceramics (LTCC). It shows the possibility for the integration of the bioreceptor layers with structures that have been fabricated using modern microelectronic technology. Design/methodology/approach – The presented microfluidic module was fabricated using LTCC technology. The possibility for the fabrication of an enzymatic microreactor in a multilayer ceramic substrate, made of CeramTec glass ceramic (GC) material systems with an integrated thick-film heater, is studied. Different configurations of the LTCC/heater materials (gold, silvers and palladium-silver) are taken into account. The performance of the LTCC-based microfluidic module with the integrated heater and immobilized enzyme was examined experimentally. Findings – A compatible material for the heater embedded in the CeramTec GC-based structures was found. The preliminary measurements made for the test solution containing various concentrations of urea have shown stability (for seven days of operation) and a relatively high signal-to-noise ratio (above 3 pH units) for the microreactor’s output signal. Research limitations/implications – The presented research is a preliminary work which is focused on the fabrication of the LTCC-based microfluidic module, with an integrated heater and immobilized enzyme for urea determination. The device was positively tested using a model reaction of the hydrolysis of urea. However, urea concentration in real (biological) fluid should also be measured. Practical implications – The development of the LTCC-based microfluidic module for urea determination provides opportunity for the construction of a lab-on-chip, or μTAS-type system, for fast medical diagnoses and the continuous monitoring of various biochemical parameters, e.g. for estimating the effectiveness of hemodialysis. Originality/value – This paper shows the design, fabrication and performance of the novel microfluidic module for urea determination, made with LTCC technology.

Potentiometric biosensor for urea determination in milk

2009 ◽  
Vol 140 (1) ◽  
pp. 260-266 ◽  
Author(s):  
U.B. Trivedi ◽  
D. Lakshminarayana ◽  
I.L. Kothari ◽  
N.G. Patel ◽  
H.N. Kapse ◽  
...  
Keyword(s):  
Urea Determination

Application of potentiometric biosensor based on recombinant urease for urea determination in blood serum and hemodialyzate

2015 ◽  
Vol 207 ◽  
pp. 981-986 ◽  
Author(s):  
S.V. Marchenko ◽  
I.S. Kucherenko ◽  
A.N. Hereshko ◽  
I.V. Panasiuk ◽  
O.O. Soldatkin ◽  
...  
Keyword(s):  
Blood Serum ◽  
Urea Determination
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