Development of Highly Selective Interdigitated Electrode Sensor for Detection of Methylene Blue

2015 ◽  
Vol 13 (5) ◽  
pp. 349-356 ◽  
Author(s):  
Saida Zougar ◽  
Amel Sbartai ◽  
Nicole Jaffrezic-Renault ◽  
Rochdi Kherrat
Keyword(s):  
Methylene Blue ◽  
Interdigitated Electrode ◽  
Electrode Sensor

scholarly journals Ultrasensitive and label-free biosensor for the detection of Plasmodium falciparum histidine-rich protein II in saliva

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Gita V. Soraya ◽  
Chathurika D. Abeyrathne ◽  
Christelle Buffet ◽  
Duc H. Huynh ◽  
Shah Mukim Uddin ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Malaria Elimination ◽  
Point Of Care ◽  
Turnaround Time ◽  
Label Free ◽  
Global Public Health ◽  
Interdigitated Electrode ◽  
Sensor Platform ◽  
Electrode Sensor ◽  
Phosphate Buffered Saline

AbstractMalaria elimination is a global public health priority. To fulfil the demands of elimination diagnostics, we have developed an interdigitated electrode sensor platform targeting the Plasmodium falciparum Histidine Rich Protein 2 (PfHRP2) protein in saliva samples. A protocol for frequency-specific PfHRP2 detection in phosphate buffered saline was developed, yielding a sensitivity of 2.5 pg/mL based on change in impedance magnitude of the sensor. This protocol was adapted and optimized for use in saliva with a sensitivity of 25 pg/mL based on change in resistance. Further validation demonstrated detection in saliva spiked with PfHRP2 from clinical isolates in 8 of 11 samples. With a turnaround time of ~2 hours, the label-free platform based on impedance sensors has the potential for miniaturization into a point-of-care diagnostic device for malaria elimination.

scholarly journals Anxiety determination by antibody-conjugated nanoparticles on an interdigitated electrode sensor

3 Biotech ◽  
2020 ◽  
Vol 10 (9) ◽  
Author(s):  
Xijian Wang ◽  
Subash C. B. Gopinath ◽  
Jiexing Li
Keyword(s):  
Interdigitated Electrode ◽  
Electrode Sensor

scholarly journals Gold Nanorod Integrated Electrochemical Sensing for Hyperglycaemia on Interdigitated Electrode

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Shumin Zheng ◽  
Hong Zhang ◽  
Thangavel Lakshmipriya ◽  
Subash C. B. Gopinath ◽  
Na Yang
Keyword(s):  
Blood Sugar ◽  
Blood Sugar Level ◽  
Continuous Monitoring ◽  
Gold Nanorod ◽  
Electrochemical Sensing ◽  
Glucose Detection ◽  
Interdigitated Electrode ◽  
Electrode Sensor ◽  
Test Frame

Gestational diabetes (hyperglycaemia) is an elevated blood sugar level diagnosed during the period of pregnancy and affects the baby’s health. Hyperglycaemia has been found within the gestational weeks between 24 and 28, and the foetus has also the possibility of getting out prior to this test frame; it causes excessive birth weight, early birth, low-blood sugar level, respiratory distress syndrome, and type-2 diabetes to the mother. It creates a mandatory situation to identify the hyperglycaemia at least during the pregnancy weeks from 18 to 20. Further, a continuous monitoring of the level of glucose is necessary for the proper delivery. In this work, a method is introduced for glucose detection at 0.06 mg/mL, assisted by gold nanorod (GNR)-conjugated glucose oxidase (GOx) on interdigitated electrode sensor. In the absence of GNR, GOx shows the limit of glucose detection to be 0.25 mg/mL. Moreover, with GOx-GNR the reactions of all the glucose concentrations have recorded higher levels of the current from the baseline. With the specificity analysis, it was found that the glucose only reacts with GOx-GNR and discriminates other sugars efficiently. This method of detection is useful to diagnose and continuously monitor the glucose level during the pregnancy period.

scholarly journals Poly(methylene blue) modified electrode sensor for haemoglobin

1999 ◽  
Vol 385 (1-3) ◽  
pp. 119-123 ◽  
Author(s):  
Christopher M.A Brett ◽  
György Inzelt ◽  
Vilmos Kertesz
Keyword(s):  
Methylene Blue ◽  
Modified Electrode ◽  
Electrode Sensor
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