MDA-MB-231 Cell Beads Surrounded by Human Umbilical Vein Endothelial Cells for the In Vitro Study of Tumor Cell Intravasation

2017 ◽  
Vol 9 (9) ◽  
pp. 1510-1516
Author(s):  
Viet Duc Nguyen ◽  
Changyoon Baek ◽  
Donghyun Lee ◽  
Junhong Min
Keyword(s):  
Endothelial Cells ◽  
Tumor Cell ◽  
Umbilical Vein ◽  
In Vitro Study ◽  
Vitro Study ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells

scholarly journals Effect of TNFα stimulation on expression of kidney risk inflammatory proteins in human umbilical vein endothelial cells cultured in hyperglycemia

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zaipul I. Md Dom ◽  
Caterina Pipino ◽  
Bozena Krolewski ◽  
Kristina O’Neil ◽  
Eiichiro Satake ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
Systemic Exposure ◽  
In Vitro Study ◽  
Human Umbilical Vein ◽  
Intracellular Fraction ◽  
Inflammatory Proteins ◽  
Umbilical Vein Endothelial Cells ◽  
Extracellular Fraction

AbstractWe recently identified a kidney risk inflammatory signature (KRIS), comprising 6 TNF receptors (including TNFR1 and TNFR2) and 11 inflammatory proteins. Elevated levels of these proteins in circulation were strongly associated with risk of the development of end-stage kidney disease (ESKD) during 10-year follow-up. It has been hypothesized that elevated levels of these proteins in circulation might reflect (be markers of) systemic exposure to TNFα. In this in vitro study, we examined intracellular and extracellular levels of these proteins in human umbilical vein endothelial cells (HUVECs) exposed to TNFα in the presence of hyperglycemia. KRIS proteins as well as 1300 other proteins were measured using the SOMAscan proteomics platform. Four KRIS proteins (including TNFR1) were down-regulated and only 1 protein (IL18R1) was up-regulated in the extracellular fraction of TNFα-stimulated HUVECs. In the intracellular fraction, one KRIS protein was down-regulated (CCL14) and 1 protein was up-regulated (IL18R1). The levels of other KRIS proteins were not affected by exposure to TNFα. HUVECs exposed to a hyperglycemic and inflammatory environment also showed significant up-regulation of a distinct set of 53 proteins (mainly in extracellular fraction). In our previous study, circulating levels of these proteins were not associated with progression to ESKD in diabetes.

scholarly journals Effect of Extract of Pomegranate (Punica granatum L.) on Glycated Protein-iron Chelate-induced Toxicity: An In Vitro Study on Human Umbilical-vein Endothelial Cells

2008 ◽  
Vol 54 (4) ◽  
pp. 441-449 ◽  
Author(s):  
Ikuo Nishigaki ◽  
Peramaiyan Rajendran ◽  
Ramachandran Venugopal ◽  
Ganapathy Ekambaram ◽  
Dhanapal Sakthisekaran ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Umbilical Vein ◽  
In Vitro Study ◽  
Punica Granatum ◽  
Iron Chelate ◽  
Human Umbilical Vein ◽  
Glycated Protein ◽  
Umbilical Vein Endothelial Cells ◽  
Punica Granatum L

Effects of intravenous immunoglobulin and methylprednisolone on human umbilical vein endothelial cells in vitro

Immunobiology ◽  
2006 ◽  
Vol 211 (5) ◽  
pp. 351-357 ◽  
Author(s):  
Jong-Seo Yoon ◽  
Hyun-Hee Kim ◽  
Ji-Whan Han ◽  
Yoon Lee ◽  
Joon-Sung Lee
Keyword(s):  
Endothelial Cells ◽  
Intravenous Immunoglobulin ◽  
Umbilical Vein ◽  
Human Umbilical Vein ◽  
Umbilical Vein Endothelial Cells
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