The Effect of Chemical and Physical Characteristics of Nano Graphene Oxide Layer on Epithelial Cell Behavior

2016 ◽  
Vol 16 (11) ◽  
pp. 11882-11886 ◽  
Author(s):  
Sung Hee Chung ◽  
Changyoon Baek ◽  
Jeakwang Kim ◽  
Songhun Yoon ◽  
Junhong Min
Author(s):  
Soumitra Satapathi ◽  
Rutusmita Mishra ◽  
Manisha Chatterjee ◽  
Partha Roy ◽  
Somesh Mohapatra

Nano-materials based drug delivery modalities to specific organs and tissues has become one of the critical endeavors in pharmaceutical research. Recently, two-dimensional graphene has elicited considerable research interest because of its potential application in drug delivery systems. Here we report, the drug delivery applications of PEGylated nano-graphene oxide (nGO-PEG), complexed with a multiphoton active and anti-cancerous diarylheptanoid drug curcumin. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug curcumin due to its high surface area and easy surface functionalization. nGO was synthesized by modified Hummer’s method and confirmed by XRD analysis. The formation of nGO, nGO-PEG and nGO-PEG-Curcumin complex were monitored through UV-vis, IR spectroscopy. MTT assay and AO/EB staining found that nGO-PEG-Curcumin complex afforded highly potent cancer cell killing in vitro with a human breast cancer cell line MCF7.


ACS Nano ◽  
2019 ◽  
Vol 13 (8) ◽  
pp. 9482-9490 ◽  
Author(s):  
Qinwei Wei ◽  
Songfeng Pei ◽  
Guodong Wen ◽  
Kun Huang ◽  
Zhaohong Wu ◽  
...  

2017 ◽  
Vol 4 (23) ◽  
pp. 1700758 ◽  
Author(s):  
Guobin Jia ◽  
Jonathan Plentz ◽  
Martin Presselt ◽  
Jan Dellith ◽  
Andrea Dellith ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 77818-77829 ◽  
Author(s):  
Rana Imani ◽  
Wei Shao ◽  
Shahriar Hojjati Emami ◽  
Shahab Faghihi ◽  
Satya Prakash

The poor dispersibility of graphene-based nano-materials in aqueous media is a crucial limitation in their biological applications.


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