Regeneration of Bombyx Mori Silk by Electrospinning: A Comparative Study of the Biocompatibility of Natural and Synthetic Polymers for Tissue Engineering Applications

2007 ◽  
Vol 1 (2) ◽  
pp. 274-281 ◽  
Author(s):  
Milind Gandhi ◽  
Heejae Yang ◽  
Lauren Shor ◽  
Frank Ko
Keyword(s):  
Tissue Engineering ◽  
Comparative Study ◽  
Bombyx Mori ◽  
Synthetic Polymers ◽  
Engineering Applications ◽  
Natural And Synthetic

scholarly journals Polymeric Bioinks for 3D Hepatic Printing

Chemistry ◽  
2021 ◽  
Vol 3 (1) ◽  
pp. 164-181
Author(s):  
Joyita Sarkar ◽  
Swapnil C. Kamble ◽  
Nilambari C. Kashikar
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Soft Tissues ◽  
Three Dimensional ◽  
Stem Cell Differentiation ◽  
Synthetic Polymers ◽  
Bioactive Molecules ◽  
Complex Geometries ◽  
Printing Techniques ◽  
Natural And Synthetic

Three-dimensional (3D) printing techniques have revolutionized the field of tissue engineering. This is especially favorable to construct intricate tissues such as liver, as 3D printing allows for the precise delivery of biomaterials, cells and bioactive molecules in complex geometries. Bioinks made of polymers, of both natural and synthetic origin, have been very beneficial to printing soft tissues such as liver. Using polymeric bioinks, 3D hepatic structures are printed with or without cells and biomolecules, and have been used for different tissue engineering applications. In this review, with the introduction to basic 3D printing techniques, we discuss different natural and synthetic polymers including decellularized matrices that have been employed for the 3D bioprinting of hepatic structures. Finally, we focus on recent advances in polymeric bioinks for 3D hepatic printing and their applications. The studies indicate that much work has been devoted to improvising the design, stability and longevity of the printed structures. Others focus on the printing of tissue engineered hepatic structures for applications in drug screening, regenerative medicine and disease models. More attention must now be diverted to developing personalized structures and stem cell differentiation to hepatic lineage.

Nanosheets-incorporated bio-composites containing natural and synthetic polymers/ceramics for bone tissue engineering

2020 ◽  
Vol 164 ◽  
pp. 1960-1972
Author(s):  
S. Pranav Adithya ◽  
D. Saleth Sidharthan ◽  
R. Abhinandan ◽  
K. Balagangadharan ◽  
N. Selvamurugan
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Synthetic Polymers ◽  
Natural And Synthetic

Facile and rapid ruthenium mediated photo-crosslinking of Bombyx mori silk fibroin

2014 ◽  
Vol 2 (37) ◽  
pp. 6259-6270 ◽  
Author(s):  
Jasmin L. Whittaker ◽  
Namita R. Choudhury ◽  
Naba K. Dutta ◽  
Andrew Zannettino
Keyword(s):  
Tissue Engineering ◽  
Bombyx Mori ◽  
Silk Fibroin ◽  
Engineering Applications ◽  
Bombyx Mori Silk

We report a unique and facile way of preparing silk fibroin gel by ruthenium-mediated photocrosslinking of silk solution. Compared to existing methods, this approach is faster, taking only a few minutes to form the gel with tunable modulus. Hydrogels demonstrate their potential suitability as biomaterials for tissue engineering applications.

scholarly journals Facile modification of polycaprolactone nanofibers with egg white protein

2021 ◽  
Vol 32 (4) ◽  
Author(s):  
Nergis Zeynep Renkler ◽  
Emre Ergene ◽  
Seyda Gokyer ◽  
Merve Tuzlakoglu Ozturk ◽  
Pinar Yilgor Huri ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Low Cost ◽  
Egg White ◽  
Synthetic Polymers ◽  
Biological Properties ◽  
Homogeneous Distribution ◽  
Cellular Interactions ◽  
Engineering Applications ◽  
Egg White Protein ◽  
Wide Range

AbstractSynthetic polymers remain to be a major choice for scaffold fabrication due to their structural stability and mechanical strength. However, the lack of functional moieties limits their application for cell-based therapies which necessitate modification and functionalization. Blending synthetic polymers with natural components is a simple and effective way to achieve the desired biological properties for a scaffold. Herein, nanofibrous mats made of polycaprolactone (PCL) and egg white protein (EWP) blend were developed and further evaluated for use as a scaffold for tissue engineering applications. Homogeneous distribution of EWP was achieved throughout the nanofibrous mats, as shown by immunohistochemistry. ATR-FTIR analysis and contact angle measurements have further confirmed the presence of EWP on the surface of the samples. The swelling test showed that PCL/EWP nanofibers have higher water uptake than PCL nanofibrous mats. Also, EWP addition on the nanofibrous mats resulted in an increase in the tensile strength and Young’s modulus of the mats, indicating that the presence of protein can greatly enhance the mechanical properties of the mats. A significantly higher, more uniform, and dispersed cell spreading was observed on days 7 and 14 than that on neat PCL mats, demonstrating the importance of providing the required cues for cell homing by the availability of EWP. Hence, EWP is shown to be a simple and low-cost source for the functionalization of PCL nanofibrous mats. EWP is, therefore, a facile candidate to enhance cellular interactions of synthetic polymers for a wide range of tissue engineering applications.

scholarly journals A comparative study of tough hydrogen bonding dissipating hydrogels made with different network structures.

2021 ◽  
Author(s):  
Badri Narayanan Narasimhan ◽  
Gerrit Sjoerd Deijs ◽  
Sesha Manuguri ◽  
Matthew S. Ting ◽  
Bill Williams ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hydrogen Bonding ◽  
Comparative Study ◽  
Biological Systems ◽  
Soft Materials ◽  
Network Structures ◽  
Engineering Applications ◽  
Precise Control

Hydrogels are excellent soft materials to interface with biological systems. Precise control and tunability of dissipative properties of gels are particularly interesting in tissue engineering applications. In this work, we...

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