Tyrosine Derivative of Aminoacid Produced Bio Inspired Nanotubes and NanovesiclesSynthesis and Characterization

3,5-bis(trifluoromethyl)benzylamine derivative of tyrosine single aminoacids have produced self-assembled peptide nanotubes and nanovesicles (BTTPNTs) depending on the concentration of the monomer study through optical and microscopic analysis. DFT simulations were carried out for a system of BTTPNTs and nanovesicles which also experimentally characterized by high resolution transmission electron microscopy (HR-TEM) and ultraviolet-visible (UV-Vis) absorbance. These results are used to examine the morphologies, size of the nanostructure and study its recognition of aminoacid motif is discussed. However, the length of the nanotubes gets larger with the increases of concentration. UV-Vis spectra clearly showed slight decrease in the intensity in absorption after the formation of nanotubes and nanovesicles. Theoretical calculations indicate that H-bonding is the key factor in making ring while other interactions including Van der Walls force, π–π stacking plays role to making self-assembled nanotubes and vesicles.