Depression, Anxiety, and Suicide After Stroke: A Narrative Review of the Best Available Evidence

Stroke ◽  
2021 ◽  
Author(s):  
Ho-Yan Yvonne Chun ◽  
Andrew Ford ◽  
Mansur A. Kutlubaev ◽  
Osvaldo P. Almeida ◽  
Gillian E. Mead

Depression and anxiety each affect around 1 in 3 people during the first year after a stroke. Suicide causes the death of about 3 to 4/1000 stroke survivors during the first 5 years. This narrative review describes the best available evidence for the epidemiology of depression, anxiety, and suicide; their prevention; and the treatment of anxiety and depression. We conclude with directions for future research.

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
David Plevin ◽  
Nicholas Smith

Anxiety and depression in children and adolescents with epilepsy are common comorbidities which place a significant burden on patients and families and complicate the clinical management of epilepsy. This paper presents a narrative review on the aetiology, phenomenology, assessment, and management of depression and anxiety among paediatric patients with epilepsy. The recognition of affective comorbidity in paediatric epilepsy is limited at present, and the contributory role of antiepileptic medication towards such comorbidity must be considered by clinicians.


2021 ◽  
Vol 9 (Spl-1- GCSGD_2020) ◽  
pp. S62-S70
Author(s):  
Vinodhkumar Ramalingam ◽  
◽  
Cheong Soon Keng ◽  
Poh Foong Lee ◽  
◽  
...  

Mindfulness practice has become an increasingly popular intervention in optimizing athletic performance in sports. Numerous studies have reported on applying mindfulness for improving the performance of various sports such as tennis, table tennis, shooting, cricket, archery, golf, running, hockey, swimming, and cycling. This narrative review addresses different existing mindfulness programs that enhance sports performance, the outcome measures of mindfulness therapy, and identifies the anxiety and depression that affect the performance of sports individuals. To cope with the issues, the efficacy of mindfulness in performance enhancement and future research directions on mindfulness needs attention.


2020 ◽  
Author(s):  
Arlene McGarty ◽  
Lisa McDaid ◽  
Paul Flowers ◽  
Julie Riddell ◽  
John Pachankis ◽  
...  

Abstract Background: Gay, bisexual and other men who have sex with men (GBMSM) are at a greater risk of mental health problems, such as anxiety and depression, than heterosexual adults. Numerous factors and stressors have been reported to impact men’s mental health, although it has been suggested that resilience could have a protective effect. The aim of this study is to explore mental health, minority stressors, and resilience among a large online cross-sectional survey of GBMSM in the Celtic nations. Methods: Data for this cross-sectional study were collected from the Social Media, GBMSM and Sexual and Holistic Health (SMMASH2) self-report online survey. Participants (n=3077) were recruited via gay sociosexual media in Scotland, Wales, Northern Ireland, and the Republic of Ireland. Binary logistic regression analyses were conducted to identify factors that increased the odds of moderate-to-severe anxiety and depression. Potentially relevant variables (p<0.05) were carried forward in hierarchal logistic regression analyses. Results: The prevalence of moderate-to-severe anxiety and depression was 19.9% and 14.4%, respectively. Having a disability (OR = 1.73) and having financial worries sometimes/all of the time (OR = 1.93) increased the odds of having moderate-to-severe depression and anxiety, respectively. No minority stressors were associated with depression, whereas experiencing any form of relationship abuse in the last 12 months significantly increased the odds of anxiety (OR = 1.50). Resilience, namely a sense of coherence, had a protective effect and significantly reduced the odds of moderate-to-severe depression (OR = 0.85) and anxiety (OR = 0.89). Discussion: Disability and financial worries were associated with increased depression and anxiety, respectively, while resilience had a protective effect for GBMSM in the SMMASH2 study. Future research is needed to better understand the role of resilience and the challenges and stresses of everyday life and intersecting health problems. Future research is also needed that incorporates the perspectives of those most affected by mental ill-health to co-develop effective solutions that respond to their contextual surroundings.


2020 ◽  
Vol 48 (1) ◽  
pp. 129-137 ◽  
Author(s):  
Alyssa Howren ◽  
Drew Bowie ◽  
Hyon K. Choi ◽  
Sharan K. Rai ◽  
Mary A. De Vera

Objective.To conduct a systematic review of depression and anxiety among patients with gout that specifically evaluates the prevalence, incidence, determinants, and effects of these mental health comorbidities.Methods.We conducted a literature search in Medline, Embase, Cochrane Database of Systematic Reviews, CINAHL, and PsycINFO using indexed terms and key words to identify studies reporting on depression/anxiety in patients with gout. This review included full-text articles published in English that reported on patients with gout, evaluated depression/anxiety using a routinely reported measure, and provided estimates or sufficient data on the prevalence, incidence, determinants, or effects of depression/anxiety. Metaanalyses were conducted using random effects models.Results.Twenty of 901 articles identified through the search strategy met our inclusion criteria. All 20 studies evaluated depression, while only 10 assessed anxiety (50%). Metaanalyses suggest a positive association between mental health disorders and gout, as resultant pooled OR were 1.29 (95% CI 1.07–1.56) for depression and 1.29 (95% CI 0.96–1.73) for anxiety. Findings from four studies reporting on the incidence of depression in patients with gout resulted in a pooled HR of 1.17 (95% CI 1.01–1.36). Significant determinants of depression included number of tophi, frequency of flares, and oligo/polyarticular gout.Conclusion.Our systematic review suggests that depression and anxiety are significantly associated with gout, highlighting the need for future research to focus on the onset of mental disorders after gout diagnosis. We also identify potential targets for intervention.


Medicina ◽  
2020 ◽  
Vol 56 (3) ◽  
pp. 117 ◽  
Author(s):  
Andrzej Knapik ◽  
Ewa Krzystanek ◽  
Justyna Szefler–Derela ◽  
Joanna Siuda ◽  
Jerzy Rottermund ◽  
...  

The main arguments in support of researching anxiety and depression in patients with chronic somatic diseases are the prevalence of affective disorders in the population, somatic conditions as risk factors of affective disorders and the search for effective preventative and therapeutic strategies. The aim of the study was to determine the association between the functional status, selected sociodemographic characteristics and prevalence as well as severity of anxiety and depression in patients with multiple sclerosis (MS), Parkinson’s disease (PD) and history of stroke (S). Material and methods: Eighty participants (44 women and 36 men) with MS (n = 22), PD (n = 31) and history of stroke (n = 27) were enrolled. All participants completed a questionnaire consisting of metrics, the Katz Index of Independence in Activities of Daily Living and the Hospital Anxiety and Depression Scale (HADS). Results: Fifty-five per cent of all participants did not present with anxiety or depression, 20% scored above the diagnostic threshold on the anxiety scale and 26% scored above the diagnostic threshold on the depression scale. Subgroup analysis revealed that anxiety and depression sufferers were 13.64% and 13.64% of MS patients, respectively; 22.58% and 35.48% of PD patients, respectively; and 22.22% and 25.93% of stroke survivors, respectively. There was a significant correlation between depression and independence level in the entire group and between depression and marital status in stroke survivors. Conclusions: Although depression and anxiety are highly prevalent in patients with neurological conditions, the disorder has a very individual nature and is not associated with the patient’s age, duration of a condition or concomitant diseases. Screening for depression and anxiety as a part of comprehensive approach may increase treatment efficacy in neurological patients


1993 ◽  
Vol 72 (3_suppl) ◽  
pp. 1145-1146 ◽  
Author(s):  
Steven E. Schneider ◽  
Walter M. Phillips

The adaptive demands of a physicians' residency program include relocation to another area, mastery of a new organizational system, and a new level of role responsibility, in addition to education and patient care activities. This study examined the prevalence of significant psychiatric symptoms in medical, surgical, and pediatric interns for three four-month intervals. Following a cohort of 39 residents over the course of their first year, using the SCL-90—R, there was an elevated prevalence ( M = 35%) of significant anxiety and depression throughout the year. Given the consistent high anxiety and depression, more research needs to be undertaken to understand the interaction of initial and ongoing adaptive demands.


2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mary Ann Taylor ◽  
Amber Nicole Neal ◽  
Jana Schellinger ◽  
Stephanie Ostrowski ◽  
Amelia White ◽  
...  

Background: Research has shown that students in the health sciences experience higher levels of anxiety and depression. Objectives: In this study, we endeavor to investigate these results among first-year pharmacy and veterinary students at Auburn University and among first-year medical students at the Edward Via College of Osteopathic Medicine’s (VCOM) Auburn Campus. Methods: We surveyed students after their first year in their respective professional programs using a modified Hospital Anxiety and Depression scale (HADS) survey. The survey was modified to establish changes in depression and anxiety levels before and after the first year of coursework. Results: Two hundred ninety-five students participated in the survey, 95 veterinary students, 127 pharmacy students, and 73 VCOM students. All programs showed a statistically significant increase in student-reported levels of depression and anxiety. Students from the Harrison School of Pharmacy showed the greatest increase in anxiety and depression, followed by students from VCOM and the College of Veterinary Medicine. Females in all programs entered their programs with higher levels of anxiety than males and also completed their first year with higher anxiety scores than males in the same programs. Conclusions: Students in all three professional programs reported increased levels of anxiety and depression with the largest increase reported in pharmacy students. Efforts to identify the triggers, understand the consequences, and develop interventional methods to improve student wellbeing are recommended.


2019 ◽  
Author(s):  
Jeremy F Huckins ◽  
Alex W DaSilva ◽  
Elin L Hedlund ◽  
Eilis I Murphy ◽  
Courtney Rogers ◽  
...  

BACKGROUND Across college campuses, the prevalence of clinically relevant depression or anxiety is affecting more than 27% of the college population at some point between entry to college and graduation. Stress and self-esteem have both been hypothesized to contribute to depression and anxiety levels. Although contemporaneous relationships between these variables have been well-defined, the causal relationship between these mental health factors is not well understood, as frequent sampling can be invasive, and many of the current causal techniques are not well suited to investigate correlated variables. OBJECTIVE This study aims to characterize the causal and contemporaneous networks between these critical mental health factors in a cohort of first-year college students and then determine if observed results replicate in a second, distinct cohort. METHODS Ecological momentary assessments of depression, anxiety, stress, and self-esteem were obtained weekly from two cohorts of first-year college students for 40 weeks (1 academic year). We used the Peter and Clark Momentary Conditional Independence algorithm to identify the contemporaneous (t) and causal (t-1) network structures between these mental health metrics. RESULTS All reported results are significant at <i>P</i>&lt;.001 unless otherwise stated. Depression was causally influenced by self-esteem (<i>t</i>-1 <i>r</i><sub>p</sub>, cohort 1 [C1]=–0.082, cohort 2 [C2]=–0.095) and itself (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=0.388, C2=0.382) in both cohorts. Anxiety was causally influenced by stress (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=0.095, C2=0.104), self-esteem (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=–0.067, C2=–0.064, <i>P</i>=.002), and itself (<i>t</i>-1 <i>r</i><sub>p</sub>, of C1=0.293, C2=0.339) in both cohorts. A causal link between anxiety and depression was observed in the first cohort (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=0.109) and only observed in the second cohort with a more liberal threshold (<i>t</i>-1 <i>r</i><sub>p</sub>, C2=0.044, <i>P</i>=.03). Self-esteem was only causally influenced by itself (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=0.389, C2=0.393). Stress was only causally influenced by itself (<i>t</i>-1 <i>r</i><sub>p</sub>, C1=0.248, C2=0.273). Anxiety had positive contemporaneous links to depression (<i>t </i> <i>r</i><sub>p</sub>, C1=0.462, C2=0.444) and stress (<i>t </i> <i>r</i><sub>p</sub>, C1=0.354, C2=0.358). Self-esteem had negative contemporaneous links to each of the other three mental health metrics, with the strongest negative relationship being stress (<i>t </i> <i>r</i><sub>p</sub>, C1=–0.334, C2=–0.340), followed by depression (<i>t </i> <i>r</i><sub>p</sub>, C1=–0.302, C2=–0.274) and anxiety (<i>t </i> <i> r</i><sub>p</sub>, C1=–0.256, C2=–0.208). Depression had positive contemporaneous links to anxiety (previously mentioned) and stress (<i>t </i> <i> r</i><sub>p</sub>, C1=0.250, C2=0.231). CONCLUSIONS This paper is an initial attempt to describe the contemporaneous and causal relationships among these four mental health metrics in college students. We replicated previous research identifying concurrent relationships between these variables and extended them by identifying causal links among these metrics. These results provide support for the vulnerability model of depression and anxiety. Understanding how causal factors impact the evolution of these mental states over time may provide key information for targeted treatment or, perhaps more importantly, preventative interventions for individuals at risk for depression and anxiety.


2017 ◽  
Vol 27 (2) ◽  
Author(s):  
Sabrina Friis Jørgensen ◽  
Mikkel A. Auning-Hansen ◽  
Ask Elklit

The aim of the present study was to examine the influence of disability on changes in symptoms of PTSD, anxiety, and depression among treatment-seeking traumatized refugees. Eighty-one refugees participated in different rehabilitation programs. PTSD symptomatology was assessed by the HTQ-IV and symptoms of depression and anxiety were assessed by the HSCL-25. Disability was assessed by the WHODAS 2.0 before treatment. Following treatment, no statistically significant changes in PTSD, depression, and anxiety symptom scores were observed. Disability in the domain ‘getting along’ was a significant predictor of PTSD scores following treatment, when controlling for baseline scores. Neither total disability nor individual disability domains predicted any other symptom changes. Living with one’s partner did, however, seem to be a consistent and significant predictor of treatment outcome. The results are discussed in terms of clinical implications and future research needs.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Arlene McGarty ◽  
Lisa McDaid ◽  
Paul Flowers ◽  
Julie Riddell ◽  
John Pachankis ◽  
...  

Abstract Background Gay, bisexual and other men who have sex with men (GBMSM) are at a greater risk of mental health problems, such as anxiety and depression, than heterosexual adults. Numerous factors and stressors have been reported to impact men’s mental health, although it has been suggested that resilience could have a protective effect. The aim of this study is to explore mental health, minority stressors, and resilience among a large online cross-sectional survey of GBMSM in the Celtic nations. Methods Data for this cross-sectional study were collected from the Social Media, GBMSM and Sexual and Holistic Health (SMMASH2) self-report online survey. Participants (n = 3077) were recruited via gay sociosexual media in Scotland, Wales, Northern Ireland, and the Republic of Ireland. Binary logistic regression analyses were conducted to identify factors that increased the odds of moderate-to-severe anxiety and depression. Potentially relevant variables (p < 0.05) were carried forward in hierarchal logistic regression analyses. Results The prevalence of moderate-to-severe anxiety and depression was 19.9 and 14.4%, respectively. Having a disability (OR = 1.73) and having financial worries sometimes/all of the time (OR = 1.93) increased the odds of having moderate-to-severe depression and anxiety, respectively. No minority stressors were associated with depression, whereas experiencing any form of relationship abuse in the last 12 months significantly increased the odds of anxiety (OR = 1.50). Resilience, namely a sense of coherence, had a protective effect and significantly reduced the odds of moderate-to-severe depression (OR = 0.85) and anxiety (OR = 0.89). Conclusions Disability and financial worries were associated with increased depression and anxiety, respectively, while resilience had a protective effect for GBMSM in the SMMASH2 study. Future research is needed to better understand the role of resilience and the challenges and stresses of everyday life and intersecting health problems. Future research is also needed that incorporates the perspectives of those most affected by mental ill-health to co-develop effective solutions that respond to their contextual surroundings.


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