The Ambibaric Brain
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We propose a new evolutionary interpretation of the brain’s circulation that has physiological, pathophysiological, and clinical implications. We review the evidence for the concept, discuss clinical implications, and suggest techniques to address outstanding questions. We conclude that the brain circulation contains complementary low-pressure and high-pressure system that must be kept in balance for optimal brain health.
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2019 ◽
Vol 55
(4)
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pp. 751-760
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