scholarly journals Stem Cell Transplantation for Ischemic Stroke

Stroke ◽  
2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Giorgio B. Boncoraglio ◽  
Michela Ranieri ◽  
Anna Bersano ◽  
Eugenio A. Parati ◽  
Cinzia Del Giovane
Keyword(s):  
Stem Cell ◽  
Ischemic Stroke ◽  
Stem Cell Transplantation ◽  
Cell Transplantation

scholarly journals Stem cell transplantation for ischemic stroke

2019 ◽  
Author(s):  
Giorgio Battista Boncoraglio ◽  
Michela Ranieri ◽  
Anna Bersano ◽  
Eugenio A Parati ◽  
Cinzia Del Giovane
Keyword(s):  
Stem Cell ◽  
Ischemic Stroke ◽  
Stem Cell Transplantation ◽  
Cell Transplantation

scholarly journals Stem Cell Transplantation for Ischemic Stroke

Stroke ◽  
2011 ◽  
Vol 42 (3) ◽  
Author(s):  
Giorgio B. Boncoraglio ◽  
Anna Bersano ◽  
Livia Candelise ◽  
Brent A. Reynolds ◽  
Eugenio A. Parati
Keyword(s):  
Stem Cell ◽  
Ischemic Stroke ◽  
Stem Cell Transplantation ◽  
Cell Transplantation

scholarly journals Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering

2017 ◽  
Vol 37 (7) ◽  
pp. 2314-2319 ◽  
Author(s):  
Joshua D Bernstock ◽  
Luca Peruzzotti-Jametti ◽  
Daniel Ye ◽  
Florian A Gessler ◽  
Dragan Maric ◽  
...  
Keyword(s):  
Stem Cell ◽  
Ischemic Stroke ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Neural Stem Cell ◽  
Clinical Translation ◽  
Ischemic Brain ◽  
Cellular Therapies ◽  
Beneficial Effects ◽  
The World

Ischemic stroke continues to be a leading cause of morbidity and mortality throughout the world. To protect and/or repair the ischemic brain, a multitiered approach may be centered on neural stem cell (NSC) transplantation. Transplanted NSCs exert beneficial effects not only via structural replacement, but also via immunomodulatory and/or neurotrophic actions. Unfortunately, the clinical translation of such promising therapies remains elusive, in part due to their limited persistence/survivability within the hostile ischemic microenvironment. Herein, we discuss current approaches for the development of NSCs more amenable to survival within the ischemic brain as a tool for future cellular therapies in stroke.

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