scholarly journals Retinal Microvascular Signs and Risk of Stroke

Stroke ◽  
2012 ◽  
Vol 43 (12) ◽  
pp. 3245-3251 ◽  
Author(s):  
Ryo Kawasaki ◽  
Jing Xie ◽  
Ning Cheung ◽  
Ecosse Lamoureux ◽  
Ronald Klein ◽  
...  
Keyword(s):  
Retinal Microvascular Signs

scholarly journals Retinal microvascular signs in COVID-19

2021 ◽  
pp. bjophthalmol-2020-318236
Author(s):  
Ralene Sim ◽  
Gemmy Cheung ◽  
Daniel Ting ◽  
Edmund Wong ◽  
Tien Yin Wong ◽  
...  
Keyword(s):  
Medical History ◽  
Vital Signs ◽  
Plexiform Layer ◽  
Nasopharyngeal Swab ◽  
Inner Plexiform Layer ◽  
Cross Sectional ◽  
Imaging Device ◽  
Asymptomatic Patients ◽  
Significant Difference ◽  
Retinal Microvascular Signs

Background/aimsTo explore if retinal findings are associated with COVID-19 infection.MethodsIn this prospective cross-sectional study, we recruited participants positive for COVID-19 by nasopharyngeal swab, with no medical history. Subjects underwent retinal imaging with an automated imaging device (3D OCT-1 Maestro, Topcon, Tokyo, Japan) to obtain colour fundus photographs (CFP) and optical coherence tomographic (OCT) scans of the macula. Data on personal biodata, medical history and vital signs were collected from electronic medical records.Results108 patients were recruited. Mean age was 36.0±5.4 years. 41 (38.0%) had symptoms of acute respiratory infection (ARI) at presentation. Of 216 eyes, 25 (11.6%) had retinal signs—eight (3.7%) with microhaemorrhages, six (2.8%) with retinal vascular tortuosity and two (0.93%) with cotton wool spots (CWS). 11 eyes (5.1%) had hyper-reflective plaques in the ganglion cell-inner plexiform layer layer on OCT, of which two also had retinal signs visible on CFP (CWS and microhaemorrhage, respectively). There was no significant difference in the prevalence of retinal signs in symptomatic versus asymptomatic patients (12 (15.0%) vs 13 (9.6%), p=0.227). Patients with retinal signs were significantly more likely to have transiently elevated blood pressure than those without (p=0.03).ConclusionOne in nine had retinal microvascular signs on ocular imaging. These signs were observed even in asymptomatic patients with normal vital signs. These retinal microvascular signs may be related to underlying cardiovascular and thrombotic alternations associated with COVID-19 infection.

Retinal Microvascular Signs as Screening and Prognostic Factors for Cardiac Disease: A Systematic Review of Current Evidence

2021 ◽  
Vol 134 (1) ◽  
pp. 36-47.e7
Author(s):  
Raviv Allon ◽  
Michael Aronov ◽  
Michael Belkin ◽  
Elad Maor ◽  
Michael Shechter ◽  
...  
Keyword(s):  
Systematic Review ◽  
Prognostic Factors ◽  
Cardiac Disease ◽  
Current Evidence ◽  
Retinal Microvascular Signs

Regular aspirin use and retinal microvascular signs: the Blue Mountains Eye Study

2006 ◽  
Vol 24 (7) ◽  
pp. 1329-1335 ◽  
Author(s):  
Gerald Liew ◽  
Paul Mitchell ◽  
Stephen R Leeder ◽  
Wayne Smith ◽  
Tien Yin Wong ◽  
...  
Keyword(s):  
Blue Mountains ◽  
Regular Aspirin ◽  
Blue Mountains Eye Study ◽  
Retinal Microvascular Signs

scholarly journals Retinal Vascular Signs as Screening and Prognostic Factors for Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Current Evidence

2021 ◽  
Vol 11 (7) ◽  
pp. 665
Author(s):  
Michael Aronov ◽  
Raviv Allon ◽  
Danielle Stave ◽  
Michael Belkin ◽  
Eyal Margalit ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Current Literature ◽  
Meta Analysis ◽  
Disease Diagnosis ◽  
Current Evidence ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Retinal Microvasculature ◽  
Retinal Microvascular Signs

Background: The substantial burden of kidney disease fosters interest in new ways of screening for early disease diagnosis, especially by non-invasive imaging. Increasing evidence for an association between retinal microvascular signs and kidney disease prompted us to investigate the relevant current literature on such an association systematically by performing a meta-analysis of our findings. Methods: We scrutinized the current literature by searching PubMed and Embase databases from for clinical studies of the association between retinal microvascular signs and prevalent or incident kidney disease. After excluding cases that did not meet our criteria, we extracted relevant data from 42 published studies (9 prospective, 32 cross-sectional, and 1 retrospective). Results: Our investigation yielded significant associations between retinal vascular changes (including retinopathy and retinal vascular diameter) and kidney dysfunction (including chronic kidney disease (CKD), end-stage renal disease (ESRD), albuminuria, and estimated glomerular filtration rate (eGFR) decline). According to our meta-analysis, retinopathy was associated with ESRD (hazard ratio (HR) 2.12 (95% confidence interval CI; 1.39–3.22)) and with CKD prevalence in the general population (odds ratio (OR) 1.31 (95% CI; 1.14–1.50)), and specifically in type 2 diabetic patients (OR 1.68 (95% CI; 1.68–2.16)). CRAE was associated with prevalent CKD (OR 1.41 (95% CI; 1.09–1.82)). Conclusions: Our findings suggest that the retinal microvasculature can provide essential data about concurrent kidney disease status and predict future risk for kidney disease development and progression.

Retinal microvascular signs and risk of stroke and stroke mortality

Neurology ◽  
2005 ◽  
Vol 65 (7) ◽  
pp. 1005-1009 ◽  
Author(s):  
P. Mitchell ◽  
J. J. Wang ◽  
T. Y. Wong ◽  
W. Smith ◽  
R. Klein ◽  
...  
Keyword(s):  
Stroke Mortality ◽  
Retinal Microvascular Signs

scholarly journals Retinal Microvascular Signs, Cognitive Function, and Dementia in Older Persons

Stroke ◽  
2007 ◽  
Vol 38 (7) ◽  
pp. 2041-2047 ◽  
Author(s):  
Michelle L. Baker ◽  
Emily K. Marino Larsen ◽  
Lewis H. Kuller ◽  
Ronald Klein ◽  
Barbara E.K. Klein ◽  
...  
Keyword(s):  
Cognitive Function ◽  
Older Persons ◽  
Retinal Microvascular Signs

scholarly journals Retinal Microvascular Signs and Functional Loss in Older Persons

Stroke ◽  
2011 ◽  
Vol 42 (6) ◽  
pp. 1589-1595 ◽  
Author(s):  
Dae Hyun Kim ◽  
Anne B. Newman ◽  
Ihab Hajjar ◽  
Elsa S. Strotmeyer ◽  
Ronald Klein ◽  
...  
Keyword(s):  
Older Persons ◽  
Functional Loss ◽  
Retinal Microvascular Signs
Sign in / Sign up

Export Citation Format

Share Document