scholarly journals Mineralocorticoid Modulation of Cardiac Ryanodine Receptor Activity Is Associated With Downregulation of FK506-Binding Proteins

Circulation ◽  
2009 ◽  
Vol 119 (16) ◽  
pp. 2179-2187 ◽  
Author(s):  
Ana María Gómez ◽  
Angélica Rueda ◽  
Yannis Sainte-Marie ◽  
Laetitia Pereira ◽  
Spyros Zissimopoulos ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Binding Proteins ◽  
Receptor Activity ◽  
Fk506 Binding Proteins ◽  
Cardiac Ryanodine Receptor

FKBPs facilitate the termination of spontaneous Ca2+ release in wild-type RyR2 but not CPVT mutant RyR2

2016 ◽  
Vol 473 (14) ◽  
pp. 2049-2060 ◽  
Author(s):  
Joe Z. Zhang ◽  
Helen M.M. Waddell ◽  
Ella Wu ◽  
Jhanvi Dholakia ◽  
Chidinma A. Okolo ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Binding Proteins ◽  
Wild Type ◽  
Fk506 Binding Proteins ◽  
Cardiac Ryanodine Receptor

We show that the magnitude of Ca2+ release through the cardiac ryanodine receptor (RyR2) is controlled by the presence of FK506-binding proteins but that this regulation is lost when arrhythmogenic RyR2 mutations are present.

scholarly journals N-terminal and Central Segments of the Type 1 Ryanodine Receptor Mediate Its Interaction with FK506-binding Proteins

2013 ◽  
Vol 288 (22) ◽  
pp. 16073-16084 ◽  
Author(s):  
Tanya Girgenrath ◽  
Mohana Mahalingam ◽  
Bengt Svensson ◽  
Florentin R. Nitu ◽  
Razvan L. Cornea ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Binding Proteins ◽  
Fk506 Binding Proteins

Dominant negative suppression of Rad leads to intracellular Ca2+ overload via up-regulation of cardiac ryanodine receptor activity

2008 ◽  
Vol 45 (4) ◽  
pp. S5
Author(s):  
Mitsushige Murata ◽  
Hirotaka Yada ◽  
Hiroyuki Yamakawa ◽  
Mitsuru Murata ◽  
Satoshi Ogawa ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Dominant Negative ◽  
Receptor Activity ◽  
Cardiac Ryanodine Receptor

In vitro modulation of the cardiac ryanodine receptor activity by Homer1

2009 ◽  
Vol 458 (4) ◽  
pp. 723-732 ◽  
Author(s):  
Pierre Pouliquin ◽  
Suzy M. Pace ◽  
Angela F. Dulhunty
Keyword(s):  
Ryanodine Receptor ◽  
Receptor Activity ◽  
Cardiac Ryanodine Receptor

scholarly journals The Overexpression of S105N Mutant Rad Leads Intracellular Ca2+ Overload Via Up-Regulation of Cardiac Ryanodine Receptor Activity

2011 ◽  
Vol 27 (Supplement) ◽  
pp. OP32_5
Author(s):  
Hiroyuki Yamakawa ◽  
Mitsushige Murata ◽  
Tomoyuki Suzuki ◽  
Hirotaka Yada ◽  
Mika Mizusawa ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Receptor Activity ◽  
Cardiac Ryanodine Receptor

scholarly journals Disparities in the association of the ryanodine receptor and the FK506-binding proteins in mammalian heart

2012 ◽  
Vol 125 (7) ◽  
pp. 1759-1769 ◽  
Author(s):  
S. Zissimopoulos ◽  
S. Seifan ◽  
C. Maxwell ◽  
A. J. Williams ◽  
F. A. Lai
Keyword(s):  
Ryanodine Receptor ◽  
Binding Proteins ◽  
Mammalian Heart ◽  
Fk506 Binding Proteins

Human Cardiac Ryanodine Receptor: Preparation, Crystallization and Preliminary X-ray Analysis of the N-terminal Region

2013 ◽  
Vol 20 (11) ◽  
pp. 1211-1216 ◽  
Author(s):  
L’ubomír Borko ◽  
Július Kostan ◽  
Alexandra Zahradníkova ◽  
Vladimír Pevala ◽  
Juraj Gasperík ◽  
...  
Keyword(s):  
Ryanodine Receptor ◽  
Terminal Region ◽  
X Ray ◽  
Cardiac Ryanodine Receptor
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