scholarly journals Dose-Response Relationship Between Intracoronary Acetylcholine and Minimal Lumen Diameter in Coronary Endothelial Function Testing of Women and Men With Angina and No Obstructive Coronary Artery Disease

2020 ◽  
Vol 13 (4) ◽  
Author(s):  
Vedant S. Pargaonkar ◽  
Justin H. Lee ◽  
Eric K.H. Chow ◽  
Takeshi Nishi ◽  
Robyn L. Ball ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Endothelial Function ◽  
Dose Response ◽  
Obstructive Coronary Artery Disease ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Minimal Lumen Diameter ◽  
Artery Disease ◽  
Function Testing

Peripheral vascular endothelial function testing for the diagnosis of coronary artery disease

2004 ◽  
Vol 148 (4) ◽  
pp. 684-689 ◽  
Author(s):  
Zoltan Jambrik ◽  
Lucia Venneri ◽  
Albert Varga ◽  
Fausto Rigo ◽  
Adrian Borges ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Endothelial Function ◽  
Vascular Endothelial ◽  
Peripheral Vascular ◽  
Vascular Endothelial Function ◽  
Artery Disease ◽  
Function Testing

scholarly journals Chest pain without obstructive coronary artery disease: a case series

2020 ◽  
Vol 4 (3) ◽  
pp. 1-6
Author(s):  
Novalia P Sidik ◽  
Michael McDermott ◽  
Margaret B McEntegart ◽  
Colin Berry
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Obstructive Coronary Artery Disease ◽  
Case Series ◽  
Vasospastic Angina ◽  
Microvascular Angina ◽  
Coronary Vasomotion ◽  
Case Summary ◽  
Artery Disease ◽  
Function Testing

Abstract Background Ischaemic heart disease is a leading cause of mortality in women. Even in those without obstructive coronary artery disease (CAD), women with angina continue to have increased mortality. There are gender differences in prevalence of different pathophysiologies, including functional disorders such as microvascular and vasospastic angina. Case summary We describe four cases of angina in women with no obstructive CAD, in whom coronary function testing was performed. These four patients were diagnosed with disorders of coronary vasomotion, including vasospastic angina and different endotypes of microvascular angina. Discussion This case series highlights the different mechanisms of ischaemia in the absence of obstructive CAD. Patients with angina and no obstructive CAD classified by computed tomography coronary angiography may have myocardial ischaemia due to microvascular angina, vasospastic angina, or both. Conventional investigations risk under-diagnosing, and as a consequence under-treating, patients with these conditions. Coronary function testing, in the form of diagnostic guidewire-based tests and adjunctive acetylcholine provocation, has proven to be critical in the accurate diagnoses and appropriate management of these patients.

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