scholarly journals Hyperreactivity to bradykinin and alterations in angiotensin I conversion and bradykinin inactivation in renal hypertensive rats.

Hypertension ◽  
1982 ◽  
Vol 4 (1) ◽  
pp. 77-83 ◽  
Author(s):  
M C de Oliveira Salgado ◽  
E M Krieger
Keyword(s):  
Hypertensive Rats ◽  
Angiotensin I ◽  
Renal Hypertensive Rats ◽  
Bradykinin Inactivation

Renin Inhibitory Effect of Synthetic Phosphorylethanolamine (PE-104) in the Rat

1976 ◽  
Vol 51 (s3) ◽  
pp. 89s-91s ◽  
Author(s):  
M. Miyazaki ◽  
K. Yamamoto ◽  
K. Hosoki
Keyword(s):  
Blood Pressure ◽  
Inhibitory Effect ◽  
Renin Inhibitor ◽  
Hypertensive Rats ◽  
Angiotensin I ◽  
Renin Substrate ◽  
Plasma Angiotensin ◽  
Renal Hypertensive Rats

1. The renin inhibitory effect of 2-[4-(4′-chlorophenoxy)phenoxy - acetylamino]ethylphosphoryl - ethanolamine (PE-104) was examined both in vitro and in vivo. 2. PE-104 inhibited the rate of angiotensin formation from dog renin and renin substrate reaction. The Ki value was 2 mmol/l and the inhibition was competitive. 3. In normotensive rats, infusion of PE-104 abolished the increases of blood pressure and plasma angiotensin I concentration due to renin injection. In renal hypertensive rats, infusion of PE-104 decreased blood pressure and this was associated with a decrease of plasma angiotensin I concentration. 4. These observations confirm that PE-104 is a renin inhibitor.

Renin and Angiotensin II Receptor Gene Expression in Kidneys of Renal Hypertensive Rats

Hypertension ◽  
1995 ◽  
Vol 26 (5) ◽  
pp. 733-737 ◽  
Author(s):  
Jacques-Antoine Haefliger ◽  
Gabriela Bergonzelli ◽  
Gérard Waeber ◽  
Jean-François Aubert ◽  
Jürg Nussberger ◽  
...  
Keyword(s):  
Gene Expression ◽  
Angiotensin Ii ◽  
Receptor Gene ◽  
Angiotensin Ii Receptor ◽  
Hypertensive Rats ◽  
Receptor Gene Expression ◽  
Renal Hypertensive Rats

scholarly journals Hypotensive effects of diltiazem hydrochloride in the normotensive, spontaneously hypertensive and renal hypertensive rats

1979 ◽  
Vol 75 (2) ◽  
pp. 99-106 ◽  
Author(s):  
Masanori SATO ◽  
Sakae MURATA ◽  
Hiroshi NARITA ◽  
Midori TOMITA ◽  
Keiko YAMASHITA ◽  
...  
Keyword(s):  
Diltiazem Hydrochloride ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
Renal Hypertensive Rats

Caveolae Dysfunction Contributes to Impaired Relaxation Induced by Nitric Oxide Donor in Aorta from Renal Hypertensive Rats

2007 ◽  
Vol 323 (3) ◽  
pp. 831-837 ◽  
Author(s):  
G. J. Rodrigues ◽  
C. B. Restini ◽  
C. N. Lunardi ◽  
J. E. Moreira ◽  
R. G. Lima ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Donor ◽  
Hypertensive Rats ◽  
Renal Hypertensive Rats
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