scholarly journals Genomic Scan for Exercise Blood Pressure in the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study

Hypertension ◽  
2001 ◽  
Vol 38 (1) ◽  
pp. 30-37 ◽  
Author(s):  
Tuomo Rankinen ◽  
Ping An ◽  
Treva Rice ◽  
Guang Sun ◽  
Yvon C. Chagnon ◽  
...  
Circulation ◽  
2002 ◽  
Vol 105 (16) ◽  
pp. 1904-1908 ◽  
Author(s):  
Treva Rice ◽  
Jean-Pierre Després ◽  
Louis Pérusse ◽  
Yuling Hong ◽  
Michael A. Province ◽  
...  

2001 ◽  
Vol 170 (2) ◽  
pp. 485-492 ◽  
Author(s):  
Y Hong ◽  
J Gagnon ◽  
T Rice ◽  
L Perusse ◽  
AS Leon ◽  
...  

Familial correlation analyses were used to evaluate the familial aggregation of plasma androgens and androgen glucuronides (testosterone (TESTO), dihydrotestosterone (DHT), androstane-3 alpha,17 beta-diol glucuronide (3 alpha-DIOL-G), and androsterone glucuronide (ADT-G)) in 505 members of 99 white families and 296 members of 111 black families participating in the Health, Risk Factors, Exercise Training and Genetics (HERITAGE) Family Study. Each of these four measures was determined by RIA after separation of conjugated and unconjugated steroid using C18 column chromatography. All participants were sedentary prior to being including in this study. Significant spouse correlations, as well as parent-offspring and sibling correlations, were found for TESTO, DHT, 3 alpha-DIOL-G, and ADT-G in the white sample, suggesting that common familial environments and genes contribute to the familial resemblance. In the black sample, significant sibling and parent-offspring correlations were found for all four phenotypes, while the spouse correlation was marginally significant for 3 alpha-DIOL-G and not significant for TESTO, DHT, and ADT-G. The non-significance of spouse correlations in the black individuals may be due to the small number of spouse pairs. The maximal heritability estimates of TESTO, DHT, 3 alpha-DIOL-G, and ADT-G were 69%, 87%, 74%, and 56% for white individuals and 70%, 73%, 62%, and 48% for black individuals respectively. Sex differences in heritability estimates were found in the white individuals, but they were less dramatic in the black individuals. In conclusion, plasma levels of androgens and androgen glucuronides are highly heritable in both white individuals and black individuals. There are notable sex differences in the white individuals.


2004 ◽  
Vol 101 (15) ◽  
pp. 5512-5517 ◽  
Author(s):  
E. H. Sklan ◽  
A. Lowenthal ◽  
M. Korner ◽  
Y. Ritov ◽  
D. M. Landers ◽  
...  

2021 ◽  
Vol 7 (3) ◽  
pp. 302-312
Author(s):  
KS Oritogun ◽  
OO Oyewole

Background: Stroke is one of the major public health problems worldwide. Physical and mental health data of stroke survivors are often expressed in proportions. Therefore, the Beta Regression models family for data between zero and one will be appropriate. Objectives: To identify a suitable model and the likely risk factors of physical and mental health of stroke survivors. Method: Secondary data of stroke survivors from two tertiary health Institutions in Ogun State, Nigeria, were analysed. Inflated Beta (BEINF) and Inflated-at-one-Beta (BEINF1) models were compared using Deviance (DEV), Akaike Information Criterion (AIC) and Bayesian Information Criteria (BIC) for model selection. The model with minimum DEV, AIC and BIC was considered to be better. Results: The deviance (-86.0604,), AIC (-46.0604) and BIC (6.4391) values of the BEINF1 model for physical health and the deviance (-20.1217), AIC (19.8783) and BIC (72.3778) values of BEINF1 model for mental health were smaller than BEINF models. Therefore, BEINF1 was the better model to identify the health risk factors of stroke survivors. Age, marital status, diastolic blood pressure, disability duration and systolic blood pressure had a significant association with physical health, while BMI had a significant positive association with mental health.  Conclusion: The beta-inflated-at-one (BEINF1) model is suitable for identifying health risk factors of stroke survivors when the outcome variable is a proportion. Both demographic and clinical characteristics were significantly associated with the health of stroke survivors. This study would assist researchers in knowing the appropriate model for analysing proportion or percentage response variables.


2021 ◽  
Vol 4 (1) ◽  
pp. 13-20
Author(s):  
Septian Emma Dwi Jatmika

Abstract:  Jaranan Hamlet has never identified health risk factors related to PHBS and KADARZI. The purpose of this service is to find out the lowest indicators of PHBS and KADARZI. The methods used are program socialization, data analysis, and problem priority determination, Hamlet Community Deliberation (MMD), intervention, and partner participation. The results obtained, the priority problem in RT 10 and 11 Dusun Jaranan is the low number of people who do not do physical activity every day. It was agreed to be held together and blood pressure measurement before and after exercise. People are very enthusiastic and experience a decrease in blood pressure after participating in gymnastics. It is hoped that this community service program in the form of community empowerment can be used as a motivation for the community to routinely do gymnastics which can be beneficial for residents.Keywords: identification of health risk factors; community empowerment; gymnastics Abstrak: Dusun Jaranan belum pernah dilakukan identifikasi faktor risiko kesehatan terkait dengan PHBS dan KADARZI. Tujuan pengabdian ini untuk mengetahui indikator dari PHBS dan KADARZI yang paling rendah. Metode yang digunakan yaitu sosialisasi program, analisis data dan penentuan prioritas masalah, Musyawarah Masyarakat Dusun (MMD), intervensi, dan partisipasi mitra. Hasil yang didapatkan, prioritas masalah di RT 10 dan 11 Dusun Jaranan yaitu masih rendahnya masyarakat yang tidak melakukan aktifitas fisik setiap hari. Disepakati untuk diadakan senam bersama dan pengukuran tekanan darah sebelum dan sesudah senam. Masyarakat sangat antusisas dan mengalami penurunan tekanan darah setelah mengikuti senam. Diharapkan dengan adanya program pengabdian berupa pemberdayaan masyarakat ini dapat dijadikan motivasi masyarakat untuk rutin mengadakan senam yang dapat bermanfaat bagi warga.Kata kunci: identifikasi faktor risiko kesehatan; pemberdayaan masyarakat; senam


2018 ◽  
Vol 12 (3) ◽  
pp. 182-189 ◽  
Author(s):  
Diego Giulliano Destro Christofaro ◽  
Arthur E. Mesas ◽  
Raphael M. Ritti Dias ◽  
Rômulo A. Fernandes ◽  
Bruna T.C. Saraiva ◽  
...  

2020 ◽  
Vol 22 (3) ◽  
Author(s):  
Niloofar Karimi ◽  
Valiollah Dabidi Roshan ◽  
Fabio Esposito

Background: Cardiorespiratory Fitness (CRF) and its associated modifiable and non-modifiable health risk factors are very important in clinical studies. Objectives: This study aimed to compare health risk factors affecting CRF between Iranian and Italian male and female exercise science students. The correlation between VO2max and these factors was also evaluated. Methods: The sample consisted of 87 sport science students from the University of Milan (25 males and 17 females) and the University of Mazandaran (20 males and 25 females) aged 23.69 ± 1.95 years. The level of Physical Activity (PA) and body composition indices were obtained as health risk factors. Then, CRF was assessed by the Bruce test. Rate Pressure Product (RPP), blood pressure, and Heart Rate (HR) were measured before, in the end, and six minutes after the end of the test. Results: Statistical analyses revealed significant differences in RPP, Systolic Blood Pressure (SBP) during exercise, resting SBP, and Waist-to-Height Ratio (WHtR) between Iranian and Italian males and significant differences in Waist-to-Hip Ratio (WHR) and body fat percentage between Iranian and Italian females (P < 0.05). The relationships between VO2max and resting RPP, resting HR, heart rate recovery, step counts, and vigorous PA were significant in all groups (P < 0.05). Conclusions: As an assessment of VO2max, CRF is associated with hemodynamics and health risk factors. Age, sex, ethnicity, lifestyle, and culture of people in different geographical regions can affect health risk factors.


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