Activation of Angiotensin-Generating Systems in the Developing Rat Kidney

Hypertension ◽  
1996 ◽  
Vol 27 (2) ◽  
pp. 281-286 ◽  
Author(s):  
Igor V. Yosipiv ◽  
Samir S. El-Dahr
Keyword(s):  
Rat Kidney ◽  
Developing Rat

scholarly journals Ultracytochemical study of the ouabain-sensitive, K-dependent p-nitrophenylphosphatase (Na-K-ATPase) activity in the developing rat kidney.

1982 ◽  
Vol 15 (3) ◽  
pp. 421-438 ◽  
Author(s):  
HIROSHI MAYAHARA ◽  
TAKAO ANDO ◽  
YOSHIMARO ISHIKAWA ◽  
Kazuo OGAWA
Keyword(s):  
Atpase Activity ◽  
Rat Kidney ◽  
Developing Rat

scholarly journals QUANTITATIVE HISTOCHEMISTRY OF URIDINE DIPHOSPHOGLUCOSE-PYROPHOSPHATASE AND URIDINE DIPHOSPHOGLUCOSE-PYROPHOSPHORYLASE IN DEVELOPING RAT KIDNEY

1974 ◽  
Vol 22 (11) ◽  
pp. 1034-1038 ◽  
Author(s):  
CLINTON N. CORDER ◽  
MARK L. BERGER ◽  
OLIVER H. LOWRY
Keyword(s):  
Rat Kidney ◽  
Development Activity ◽  
Quantitative Histochemistry ◽  
Small Arteries ◽  
Straight Tubule ◽  
Adult Kidney ◽  
Straight Tubules ◽  
Proximal Straight Tubule ◽  
Developing Rat ◽  
Made In

Quantitative histochemical measurements of two enzymes of uridine diphosphoglucose (UDPG) metabolism have been made in the developing rat kidney nephron. Kidneys were examined from -4 days to 44 days of age. In the adult kidney, UDPG-pyrophosphatase was concentrated in proximal convoluted and straight tubules. During maturation, activity decreased in glomeruli, increased in the proximal tubule and changed little elsewhere in the nephron. UDPG-pyrophosphorylase revealed a different pattern. Activity was more nearly uniformly distributed throughout the nephron but was highest in the proximal straight tubule and ascending limb of Henle. During development, activity was unchanged or increased in glomeruli and small arteries and increased elsewhere, particularly in the proximal straight tubule and ascending limb of Henle.

Age-dependent expression of protein phosphatase 2A in the developing rat kidney

1999 ◽  
Vol 13 (9) ◽  
pp. 800-805 ◽  
Author(s):  
J. Svennilson ◽  
A.-C. Sandberg-Nordqvist ◽  
A. Aperia
Keyword(s):  
Protein Phosphatase ◽  
Rat Kidney ◽  
Protein Phosphatase 2A ◽  
Age Dependent ◽  
Phosphatase 2A ◽  
Developing Rat

Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney

2008 ◽  
Vol 588 (1) ◽  
pp. 114-123 ◽  
Author(s):  
Susana I. Sánchez ◽  
Alicia M. Seltzer ◽  
Lucia B. Fuentes ◽  
Myriam L. Forneris ◽  
Gladys M. Ciuffo
Keyword(s):  
Angiotensin Ii ◽  
Rat Kidney ◽  
Angiotensin Ii Receptors ◽  
Developing Rat

scholarly journals Aldose reductase and sorbitol dehydrogenase distribution in rat kidney.

1977 ◽  
Vol 25 (1) ◽  
pp. 1-8 ◽  
Author(s):  
C N Corder ◽  
J G Collins ◽  
T S Brannan ◽  
J Sharma
Keyword(s):  
Aldose Reductase ◽  
Alloxan Diabetes ◽  
Rat Kidney ◽  
Sorbitol Dehydrogenase ◽  
Outer Medulla ◽  
Developing Kidney ◽  
Enzymatic Changes ◽  
Developing Rat ◽  
Convoluted Tubules ◽  
Sorbitol Pathway

The sorbitol pathway catalyzes the conversion of glucose to fructose via the intermediate sorbitol. It consists of aldose reductase (AR) and sorbitol dehydrogenase (SDH). In adult (44 day) kidney zones, AR was highest in the outer medulla. In substructures AR was highest in distal convoluted tubule. The AR was greatest in newborn and 8-day zones of developing rat kidney. Acute alloxan diabetes was associated with decreased AR in small arteries, but not glomeruli. The SDH was lowest in outer medulla. It was most active in glomeruli and distal convoluted tubules. The diabetic state leads to no change of SDH in arteries but an increase in glomeruli. SDH increased with development. This study demonstrates AR and SDH in substructures of the kidney. The pathway is present in developing kidney. In diabetes the enzymatic changes would tend to decrease accumulation of sorbitol.

Toxicity of mercuric chloride to the developing rat kidney. II. Effect of increased dosages on renal function in suckling pups

1984 ◽  
Vol 74 (1) ◽  
pp. 35-45 ◽  
Author(s):  
George P. Daston ◽  
Jacqueline A. Gray ◽  
Brenda Carver ◽  
Robert J. Kavlock
Keyword(s):  
Renal Function ◽  
Mercuric Chloride ◽  
Rat Kidney ◽  
Developing Rat
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