A Novel Xenograft Bon e Substitute Supports Stable Bone Formation in Circumferential Defects Around Dental Implants in Minipigs

2020 ◽  
Vol 35 (6) ◽  
pp. 1122-1131
Author(s):  
Sylvain Catros ◽  
Rebecca Sandgren ◽  
Benjamin Pippenger ◽  
Jean Fricain ◽  
Valentin Herber ◽  
...  
2020 ◽  
Vol 18 ◽  
pp. 228080002097517
Author(s):  
Yuan-ming Geng ◽  
Dong-ni Ren ◽  
Shu-yi Li ◽  
Zong-yi Li ◽  
Xiao-qing Shen ◽  
...  

Background: Poly Ether Ether Ketone (PEEK) has been considered as a potential alternative material for endosseous dental implants, for its low elastic modulus, biocompatibility, and low cost in customized device manufacture. Hydroxyapatite-incorporation is supposed to improve the poor osseointegration of PEEK. Methods: In the present study we analyzed the in vivo response of hydroxyapatite-incorporated PEEK (PEEK-HA) implants in canine tibia. PEEK-HA and PEEK implants were implanted and were examined 4 weeks and 12 weeks after implantation with radiology and histology. Commercial titanium dental implants served as controls. Results: The ratio of bone volume to tissue volume of PEEK-HA implants was higher than that of PEEK implants 4 weeks after implantation in the μ-CT analysis. The bone implant contact of PEEK and PEEK-HA implants showed no statistical difference in the histological examination, but newly-formed bone around PEEK-HA implants showed more signs of mineralization than that around PEEK implants. Conclusion: The study suggested that bone formation was improved with hydroxyapatite-incorporation in PEEK. Hydroxyapatite-incorporated PEEK implants may represent a potential material for endosseous dental implant.


Author(s):  
Carlos Fernando Almeida da Silva ◽  
Tayná Toder Santos ◽  
Idiberto José Zotarelli Filho ◽  
Elias Naim Kassis

Introduction: When a dental element is lost in the posterior region of the maxilla, there is natural reabsorption of the alveolar process and at the same time there will be pneumatization of the maxillary sinus. It will increase its volume towards the place where the roots existed and this will often make it difficult or impossible to restore implants in place. For this reason, the procedure for elevating the floor of the maxillary sinus or short implants should be performed when possible. In this context, allogeneic, xenogenous, and alloplastic bone grafts are an alternative for the treatment of bone defects in the jaws, since they avoid the need for a second surgical access. However, due to the need for processing to eliminate antigenic components, these grafts are only osteoconductive with a lower bone formation potential compared to autogenous bone grafts. Also, in this context, in the last 20 years, platelet concentrates have been proposed as regenerative materials in tissue regeneration procedures. Among the platelet concentrates proposed in the literature, PRP and FRP are found to act as autogenous platelet aggregates with osteoinductive properties. Objective: The present study aimed to conduct a wide literature review on maxillary sinus surgery using fibrin-rich plasma. Methods: Experimental and clinical studies (case reports, retrospective, prospective and randomized) with qualitative and/or quantitative analysis were included. Results: The total of 48 articles were found involving Maxillary sinus surgery, Fibrin-rich plasma, and Biomaterials, of which 22 were selected to compose the present study. Conclusion: Based on the literary findings, it was shown that the FRP is favorable for bone formation processes for dental implants, especially when combined with xenografts.


2011 ◽  
Vol 20 (2) ◽  
pp. 139-146 ◽  
Author(s):  
Yasuhiro Nakanishi ◽  
Pao-Li Wang ◽  
Morio Ochi ◽  
Kazuyo Nakanishi ◽  
Hideki Matsubara

2011 ◽  
Vol 37 (3) ◽  
pp. 319-324 ◽  
Author(s):  
Sergio Olate ◽  
Henrique Duque de Miranda Chaves Netto ◽  
Leandro Eduardo Klüppel ◽  
Renato Mazzonetto ◽  
Jose Ricardo de Albergaria-Barbosa

Abstract The clinical success of dental implants might be associated with such factors as installation technique, implant shape, size, material, and screw threads. Therefore, the aim of this study is to analyze mineralized tissue formation on the screw threads of conical and cylindrical dental implants. This study includes 7 beagle dogs that had the lower premolars extracted. Three months after bone and soft tissue repair, 2 different designs of dental implants (1 conical and 1 cylindrical) were installed in each hemimandible using a nonsubmerged technique. Both implants when installed had different shape and thread, as revealed by scanning electron microscopy. Six weeks after implant installation, animals were killed and submitted to histomorphometric analysis. Cervical, middle, and apical areas were analyzed. Statistical analysis was carried out using Student t test at a significance level of P < .05. Statistically significant differences were not found between the conical and cylindrical implants. The conical implants presented fewer threads, a smaller area, and more bone formation when compared with the cylindrical ones, without significant differences (P  =  .1226). The highest values concerning bone formation were observed for the cervical area (P  =  .4005), and the lowest for the apical area (P  =  .1899); however, no statistically significant difference was observed. In conclusion, no statistically significant difference was observed in thread bone formation between the cylindrical and conical implant designs when placed using the nonsubmerged technique.


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